P68400: Casein kinase II subunit alpha

General Information

Protein names	- Casein kinase II subunit alpha - CK II alpha - 2.7.11.1
Gene names	CSNK2A1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P68400

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGPVPSRAR VYTDVNTHRP REYWDYESHV VEWGNQDDYQ LVRKLGRGKY SEVFEAINIT
        70         80         90        100        110        120
NNEKVVVKIL KPVKKKKIKR EIKILENLRG GPNIITLADI VKDPVSRTPA LVFEHVNNTD
       130        140        150        160        170        180
FKQLYQTLTD YDIRFYMYEI LKALDYCHSM GIMHRDVKPH NVMIDHEHRK LRLIDWGLAE
       190        200        210        220        230        240
FYHPGQEYNV RVASRYFKGP ELLVDYQMYD YSLDMWSLGC MLASMIFRKE PFFHGHDNYD
       250        260        270        280        290        300
QLVRIAKVLG TEDLYDYIDK YNIELDPRFN DILGRHSRKR WERFVHSENQ HLVSPEALDF
       310        320        330        340        350        360
LDKLLRYDHQ SRLTAREAME HPYFYTVVKD QARMGSSSMP GGSTPVSSAN MMSGISSVPT
       370        380        390
PSPLGPLAGS PVIAAANPLG MPVPAAAGAQ Q

Isoforms

- Isoform 2 of Casein kinase II subunit alpha

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P68400-1-unknown	MSGPVP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P68400-2-acetylation	SGPVPS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P68400-137-unknown	MYEILK...	137		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71872
P68400-234-unknown	HGHDNY...	234		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6167
P68400-234-unknown	HGHDNY...	234		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142270

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KEPFFH	233	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6167
...KEPFFH	233	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125460
...AGAQQ	391	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AGAQQ	391	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67490

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	233	PFFH.\|.HGHD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)