TopFIND 4.0

P70441: Na(+)/H(+) exchange regulatory cofactor NHE-RF1

General Information

Protein names
- Na(+)/H(+) exchange regulatory cofactor NHE-RF1
- NHERF-1
- Ezrin-radixin-moesin-binding phosphoprotein 50
- EBP50
- Regulatory cofactor of Na(+)/H(+) exchanger
- Sodium-hydrogen exchanger regulatory factor 1
- Solute carrier family 9 isoform A3 regulatory factor 1
Gene names Slc9a3r1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P70441

3

N-termini

2

C-termini

2

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSADAAAGEP LPRLCCLEKG PNGYGFHLHG EKGKVGQFIR LVEPGSPAEK SGLLAGDRLV 
        70         80         90        100        110        120 
EVNGENVEKE THQQVVSRIR AALNAVRLLV VDPETDERLK KLGVSIREEL LRPQEKSEQA 
       130        140        150        160        170        180 
EPPAAADTHE AGDQNEAEKS HLRELRPRLC TMKKGPNGYG FNLHSDKSKP GQFIRAVDPD 
       190        200        210        220        230        240 
SPAEASGLRA QDRIVEVNGV CMEGKQHGDV VSAIKGGGDE AKLLVVDKET DEFFKKCKVI 
       250        260        270        280        290        300 
PSQEHLDGPL PEPFSNGEIQ KESSREALVE PASESPRPAL ARSASSDTSE ELNSQDSPKR 
       310        320        330        340        350    
QVSTEPSSTS SSSSDPILDL NISLAVAKER AHQKRSSKRA PQMDWSKKNE LFSNL

Isoforms

- Isoform 2 of Na(+)/H(+) exchange regulatory cofactor NHE-RF1 - Isoform 2 of Na(+)/H(+) exchange regulatory cofactor NHE-RF1

Sequence View

        10         20         30         40         50         60 
MSADAAAGEP LPRLCCLEKG PNGYGFHLHG EKGKVGQFIR LVEPGSPAEK SGLLAGDRLV 
        70         80         90        100        110        120 
EVNGENVEKE THQQVVSRIR AALNAVRLLV VDPETDERLK KLGVSIREEL LRPQEKSEQA 
       130        140        150        160        170        180 
EPPAAADTHE AGDQNEAEKS HLRELRPRLC TMKKGPNGYG FNLHSDKSKP GQFIRAVDPD 
       190        200        210        220        230        240 
SPAEASGLRA QDRIVEVNGV CMEGKQHGDV VSAIKGGGDE AKLLVVDKET DEFFKKCKVI 
       250        260        270        280        290        300 
PSQEHLDGPL PEPFSNGEIQ KESSREALVE PASESPRPAL ARSASSDTSE ELNSQDSPKR 
       310        320        330        340        350    
QVSTEPSSTS SSSSDPILDL NISLAVAKER AHQKRSSKRA PQMDWSKKNE LFSNL         10         20         30         40         50         60 
MSADAAAGEP LPRLCCLEKG PNGYGFHLHG EKGKVGQFIR LVEPGSPAEK SGLLAGDRLV 
        70         80         90        100        110        120 
EVNGENVEKE THQQVVSRIR AALNAVRLLV VDPETDERLK KLGVSIREEL LRPQEKSEQA 
       130        140        150        160        170        180 
EPPAAADTHE AGDQNEAEKS HLRELRPRLC TMKKGPNGYG FNLHSDKSKP GQFIRAVDPD 
       190        200        210        220        230        240 
SPAEASGLRA QDRIVEVNGV CMEGKQHGDV VSAIKGGGDE AKLLVVDKET DEFFKKCKVI 
       250        260        270        280        290        300 
PSQEHLDGPL PEPFSNGEIQ KESSREALVE PASESPRPAL ARSASSDTSE ELNSQDSPKR 
       310        320        330        340        350    
QVSTEPSSTS SSSSDPILDL NISLAVAKER AHQKRSSKRA PQMDWSKKNE LFSNL



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)