P70699: Lysosomal alpha-glucosidase

General Information

Protein names	- Lysosomal alpha-glucosidase - 3.2.1.20 {ECO:0000250\|UniProtKB:P10253} - Acid maltase
Gene names	Gaa
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P70699

4 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNIRKPLCSN SVVGACTLIS LTTAVILGHL MLRELMLLPQ DLHESSSGLW KTYRPHHQEG
        70         80         90        100        110        120
YKPGPLHIQE QTEQPKEAPT QCDVPPSSRF DCAPDKGISQ EQCEARGCCY VPAGQVLKEP
       130        140        150        160        170        180
QIGQPWCFFP PSYPSYRLEN LSSTESGYTA TLTRTSPTFF PKDVLTLQLE VLMETDSRLH
       190        200        210        220        230        240
FKIKDPASKR YEVPLETPRV LSQAPSPLYS VEFSEEPFGV IVRRKLGGRV LLNTTVAPLF
       250        260        270        280        290        300
FADQFLQLST SLPSQHITGL GEHLSPLMLS TDWARITLWN RDTPPSQGTN LYGSHPFYLA
       310        320        330        340        350        360
LEDGGLAHGV FLLNSNAMDV ILQPSPALTW RSTGGILDVY VFLGPEPKSV VQQYLDVVGY
       370        380        390        400        410        420
PFMPPYWGLG FHLCRWGYSS TAIVRQVVEN MTRTHFPLDV QWNDLDYMDA RRDFTFNQDS
       430        440        450        460        470        480
FADFPDMVRE LHQDGRRYMM IVDPAISSAG PAGSYRPYDE GLRRGVFITN ETGQPLIGKV
       490        500        510        520        530        540
WPGTTAFPDF TNPETLDWWQ DMVSEFHAQV PFDGMWLDMN EPSNFVRGSQ QGCPNNELEN
       550        560        570        580        590        600
PPYVPGVVGG ILQAATICAS SHQFLSTHYN LHNLYGLTEA IASSRALVKT RGTRPFVISR
       610        620        630        640        650        660
STFSGHGRYA GHWTGDVRSS WEHLAYSVPD ILQFNLLGVP LVGADICGFI GDTSEELCVR
       670        680        690        700        710        720
WTQLGAFYPF MRNHNDLNSV PQEPYRFSET AQQAMRKAFA LRYALLPYLY TLFHRAHVRG
       730        740        750        760        770        780
DTVARPLFLE FPEDPSTWSV DRQLLWGPAL LITPVLEPGK TEVTGYFPKG TWYNMQMVSV
       790        800        810        820        830        840
DSLGTLPSPS SASSFRSAVQ SKGQWLTLEA PLDTINVHLR EGYIIPLQGP SLTTTESRKQ
       850        860        870        880        890        900
PMALAVALTA SGEADGELFW DDGESLAVLE RGAYTLVTFS AKNNTIVNKL VRVTKEGAEL
       910        920        930        940        950
QLREVTVLGV ATAPTQVLSN GIPVSNFTYS PDNKSLAIPV SLLMGELFQI SWS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P70699-28-unknown	GHLMLR...	28	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P70699-70-unknown	EQTEQP...	70	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P70699-70-unknown	EQTEQP...	70	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P70699-215-unknown	EEPFGV...	215	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P70699-827-unknown	LQGPSL...	827	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33808

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GGRVLL	231	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000101865
...HQFLST	566	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119702
...PLFLEF	730	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121984
...GYIIPL	826	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33808
...QISWS	953	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	826	IIPL.\|.LQGP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)