P78364: Polyhomeotic-like protein 1

General Information

Protein names	- Polyhomeotic-like protein 1 - hPH1 - Early development regulatory protein 1
Gene names	PHC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P78364

4 N-termini

7 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
METESEQNSN STNGSSSSGG SSRPQIAQMS LYERQAVQAL QALQRQPNAA QYFHQFMLQQ
        70         80         90        100        110        120
QLSNAQLHSL AAVQQATIAA SRQASSPNTS TTQQQTTTTQ ASINLATTSA AQLISRSQSV
       130        140        150        160        170        180
SSPSATTLTQ SVLLGNTTSP PLNQSQAQMY LRPQLGNLLQ VNRTLGRNVP LASQLILMPN
       190        200        210        220        230        240
GAVAAVQQEV PSAQSPGVHA DADQVQNLAV RNQQASAQGP QMQGSTQKAI PPGASPVSSL
       250        260        270        280        290        300
SQASSQALAV AQASSGATNQ SLNLSQAGGG SGNSIPGSMG PGGGGQAHGG LGQLPSSGMG
       310        320        330        340        350        360
GGSCPRKGTG VVQPLPAAQT VTVSQGSQTE AESAAAKKAE ADGSGQQNVG MNLTRTATPA
       370        380        390        400        410        420
PSQTLISSAT YTQIQPHSLI QQQQQIHLQQ KQVVIQQQIA IHHQQQFQHR QSQLLHTATH
       430        440        450        460        470        480
LQLAQQQQQQ QQQQQQQQQP QATTLTAPQP PQVPPTQQVP PSQSQQQAQT LVVQPMLQSS
       490        500        510        520        530        540
PLSLPPDAAP KPPIPIQSKP PVAPIKPPQL GAAKMSAAQQ PPPHIPVQVV GTRQPGTAQA
       550        560        570        580        590        600
QALGLAQLAA AVPTSRGMPG TVQSGQAHLA SSPPSSQAPG ALQECPPTLA PGMTLAPVQG
       610        620        630        640        650        660
TAHVVKGGAT TSSPVVAQVP AAFYMQSVHL PGKPQTLAVK RKADSEEERD DVSTLGSMLP
       670        680        690        700        710        720
AKASPVAESP KVMDEKSSLG EKAESVANVN ANTPSSELVA LTPAPSVPPP TLAMVSRQMG
       730        740        750        760        770        780
DSKPPQAIVK PQILTHIIEG FVIQEGAEPF PVGCSQLLKE SEKPLQTGLP TGLTENQSGG
       790        800        810        820        830        840
PLGVDSPSAE LDKKANLLKC EYCGKYAPAE QFRGSKRFCS MTCAKRYNVS CSHQFRLKRK
       850        860        870        880        890        900
KMKEFQEANY ARVRRRGPRR SSSDIARAKI QGKCHRGQED SSRGSDNSSY DEALSPTSPG
       910        920        930        940        950        960
PLSVRAGHGE RDLGNPNTAP PTPELHGINP VFLSSNPSRW SVEEVYEFIA SLQGCQEIAE
       970        980        990       1000
EFRSQEIDGQ ALLLLKEEHL MSAMNIKLGP ALKICAKINV LKET

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 7 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P78364-1-unknown	METESE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P78364-190-unknown	VPSAQS...	190	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000446388
P78364-222-unknown	MQGSTQ...	222	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440488
P78364-339-unknown	AEADGS...	339	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19293

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TTSPPL	141	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000445939
...RNVPLA	171	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437654
...LMPNGA	181	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437645
...PVSSLS	240	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437459
...AAAKKA	338	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19293
...VMDEKS	676	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000443676
...VLKET	1004	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	338	AKKA.\|.AEAD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)