P97372: Proteasome activator complex subunit 2

General Information

Protein names	- Proteasome activator complex subunit 2 - 11S regulator complex subunit beta - REG-beta - Activator of multicatalytic protease subunit 2 - Proteasome activator 28 subunit beta - PA28b - PA28beta
Gene names	Psme2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P97372

7 N-termini

6 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAKPCGVRLS GEARKQVDVF RQNLFQEADD FLCTFLPRKI ISLSQLLQED SLNVADLSSL
        70         80         90        100        110        120
RAPLDIPIPD PPPKDDEMET DKQEKKEVPK CGYLPGNEKL LALLALVKPE VWTLKEKCIL
       130        140        150        160        170        180
VITWIQHLIP KIEDGNDFGV AIQEKVLERV NAVKTKVEAF QTTISKYFSE RGDAVAKASK
       190        200        210        220        230
DTHVMDYRAL VHERDEAAYG ALRAMVLDLR AFYAELYHII SSNLEKIVNP KGEEKPSMY

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 6 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P97372-2-unknown	MAKPCG...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P97372-2-unknown	MAKPCG...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P97372-2-Acetylation	AKPCGV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P97372-2-Acetylation	AKPCGV...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P97372-40-unknown	IISLSQ...	40		inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P97372-47-unknown	LQEDSL...	47		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29094
P97372-51-unknown	SLNVAD...	51		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30358
P97372-51-unknown	SLNVAD...	51		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29095
P97372-53-unknown	NVADLS...	53		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30359
P97372-53-unknown	NVADLS...	53		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29096
P97372-142-unknown	IQEKVL...	142		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29097

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SLSQLL	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29094
...LLQEDS	50	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30358
...LLQEDS	50	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29095
...QEDSLN	52	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30359
...QEDSLN	52	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29096
...DFGVAI	141	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29097
...SERGDA	173	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000125596
...KPSMY	239	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATD_MOUSE	46	SQLL.\|.LQED	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PSME2_MOUSE @46
CATE_MOUSE	50	QEDS.\|.SLNV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PSME2_MOUSE @50
CATD_MOUSE	50	QEDS.\|.SLNV	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PSME2_MOUSE @50
CATE_MOUSE	52	DSLN.\|.NVAD	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PSME2_MOUSE @52
CATD_MOUSE	52	DSLN.\|.NVAD	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PSME2_MOUSE @52
CATD_MOUSE	141	GVAI.\|.IQEK	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PSME2_MOUSE @141

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)