P97467: Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000250|UniProtKB:P19021}
| Protein names | - Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000250|UniProtKB:P19021} - PAM {ECO:0000250|UniProtKB:P19021} - Peptidylglycine alpha-hydroxylating monooxygenase {ECO:0000250|UniProtKB:P19021} - PHM {ECO:0000250|UniProtKB:P19021} - 1.14.17.3 {ECO:0000250|UniProtKB:P19021} - Peptidyl-alpha-hydroxyglycine alpha-amidating lyase - 4.3.2.5 {ECO:0000250|UniProtKB:P19021} - Peptidylamidoglycolate lyase {ECO:0000250|UniProtKB:P19021} - PAL {ECO:0000250|UniProtKB:P19021} |
|---|---|
| Gene names | Pam |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P97467 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAGRARSRLL LLLGLLALQS SCLAFRSPLS VFKRFKETTR SFSNECLGTT RPITPIDSSD
70 80 90 100 110 120
FTLDIRMPGV TPKESDTYFC MSMRLPVDEE AFVIDFKPRA SMDTVHHMLL FGCNMPSSTG
130 140 150 160 170 180
SYWFCDEGTC TDKANILYAW ARNAPPTRLP KGVGFRVGGE TGSKYFVLQV HYGDISAFRD
190 200 210 220 230 240
NHKDCSGVSL HLTRVPQPLI AGMYLMMSVN TVIPPGEKVV NSDISCHYKM YPMHVFAYRV
250 260 270 280 290 300
HTHHLGKVVS GYRVRNGQWT LIGRQSPQLP QAFYPVEHPV DVAFGDILAA RCVFTGEGRT
310 320 330 340 350 360
EATHIGGTSS DEMCNLYIMY YMEAKHAVSF MTCTQNVAPD MFRTIPEEAN IPIPVKSDMV
370 380 390 400 410 420
MIHGHHKETE NKEKSALIQQ PKQGEEEAFE QGDFYSLLSK LLGEREDVVH VHKYNPTEKT
430 440 450 460 470 480
ESGSDLVAEI ANVVQKKDLG RSDAREGAEH EEGGNAILVR DRIHKFHRLE STLRPAESRA
490 500 510 520 530 540
LSFQQPGEGP WEPELAGDFH VEEALEWPGV YLLPGQVSGV ALDSKNNLVI FHRGDHVWDG
550 560 570 580 590 600
NSFDSKFVYQ QRGLGPIEED TILVIDPNKA EILQSSGKNL FYLPHGLSID TDGNYWVTDV
610 620 630 640 650 660
ALHQVFKLEP RSKEGPLLVL GRSMQPGSDQ NHFCQPTDVA VEPSTGAVFV SDGYCNSRIV
670 680 690 700 710 720
QFSPSGKFIT QWGEESSGSS PKPGQFSVPH SLALVPHLNQ LCVADRENGR IQCFKTDTKE
730 740 750 760 770 780
FVREIKHASF GRNVFAISYI PGFLFAVNGK PYFGDQEPVQ GFVMNFSSGE IIDVFKPVRK
790 800 810 820 830 840
HFDMPHDIVA SEDGTVYIGD AHTNTVWKFT LTESRLEVEH RSVKKAGIEV PEIKEAEAVV
850 860 870 880 890 900
EPKVKNKPTS SELQKMQEKK KLIKDPGSGV PVVLITTLLV IPVVVLLAIA MFIRWKKSRA
910 920 930 940 950 960
FGDHDRKLES SSGRVLGRLR GKGSSGLNLG NFFASRKGYS RKGFDRVSTE GSDQEKDEDD
970
GSESEEEYSA PLPTPAPSS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P97467-25-unknown | FRSPLS... | 25 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P97467-25-unknown | FRSPLS... | 25 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
| P97467-35-unknown | FKETTR... | 35 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P97467-35-unknown | FKETTR... | 35 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34727 | |||
| P97467-35-unknown | FKETTR... | 35 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...SVFKRF | 34 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34727 | |||
| ...PAPSS | 979 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| NEC2_MOUSE | 34 | FKRF.|.FKET | inferred from experiment | unknown | MEROPS | Fricker LD | Pan H et al.:The role of prohormone converta... (S08.073) | 16903874, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|