P97857: A disintegrin and metalloproteinase with thrombospondin motifs 1
Protein names | - A disintegrin and metalloproteinase with thrombospondin motifs 1 - ADAM-TS 1 - ADAM-TS1 - ADAMTS-1 - 3.4.24.- |
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Gene names | Adamts1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | M12.222 |
Chromosome location | |
UniProt ID | P97857 |
4
N-termini
3
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MQPKVPLGSR KQKPCSDMGD VQRAARSRGS LSAHMLLLLL ASITMLLCAR GAHGRPTEED
70 80 90 100 110 120
EELVLPSLER APGHDSTTTR LRLDAFGQQL HLKLQPDSGF LAPGFTLQTV GRSPGSEAQH
130 140 150 160 170 180
LDPTGDLAHC FYSGTVNGDP GSAAALSLCE GVRGAFYLQG EEFFIQPAPG VATERLAPAV
190 200 210 220 230 240
PEEESSARPQ FHILRRRRRG SGGAKCGVMD DETLPTSDSR PESQNTRNQW PVRDPTPQDA
250 260 270 280 290 300
GKPSGPGSIR KKRFVSSPRY VETMLVADQS MADFHGSGLK HYLLTLFSVA ARFYKHPSIR
310 320 330 340 350 360
NSISLVVVKI LVIYEEQKGP EVTSNAALTL RNFCSWQKQH NSPSDRDPEH YDTAILFTRQ
370 380 390 400 410 420
DLCGSHTCDT LGMADVGTVC DPSRSCSVIE DDGLQAAFTT AHELGHVFNM PHDDAKHCAS
430 440 450 460 470 480
LNGVSGDSHL MASMLSSLDH SQPWSPCSAY MVTSFLDNGH GECLMDKPQN PIKLPSDLPG
490 500 510 520 530 540
TLYDANRQCQ FTFGEESKHC PDAASTCTTL WCTGTSGGLL VCQTKHFPWA DGTSCGEGKW
550 560 570 580 590 600
CVSGKCVNKT DMKHFATPVH GSWGPWGPWG DCSRTCGGGV QYTMRECDNP VPKNGGKYCE
610 620 630 640 650 660
GKRVRYRSCN IEDCPDNNGK TFREEQCEAH NEFSKASFGN EPTVEWTPKY AGVSPKDRCK
670 680 690 700 710 720
LTCEAKGIGY FFVLQPKVVD GTPCSPDSTS VCVQGQCVKA GCDRIIDSKK KFDKCGVCGG
730 740 750 760 770 780
NGSTCKKMSG IVTSTRPGYH DIVTIPAGAT NIEVKHRNQR GSRNNGSFLA IRAADGTYIL
790 800 810 820 830 840
NGNFTLSTLE QDLTYKGTVL RYSGSSAALE RIRSFSPLKE PLTIQVLMVG HALRPKIKFT
850 860 870 880 890 900
YFMKKKTESF NAIPTFSEWV IEEWGECSKT CGSGWQRRVV QCRDINGHPA SECAKEVKPA
910 920 930 940 950 960
STRPCADLPC PHWQVGDWSP CSKTCGKGYK KRTLKCVSHD GGVLSNESCD PLKKPKHYID
FCTLTQCS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P97857-49-unknown | ARGAHG... | 49 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P97857-252-unknown | KRFVSS... | 252 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32217 | |||
P97857-254-unknown | FVSSPR... | 254 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P97857-264-unknown | MLVADQ... | 264 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000118471 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GSIRKK | 251 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32217 | |||
...DGGVLS | 944 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000118471 | |||
...LTQCS | 968 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
FURIN_MOUSE | 251 | IRKK.|.KRFV | inferred from experiment | unknown | MEROPS | Matsushima K | Kuno K et al.:ADAMTS-1 is an active metallopr... (S08.071) | 10373500, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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