P99029: Peroxiredoxin-5, mitochondrial

General Information

Protein names	- Peroxiredoxin-5, mitochondrial - 1.11.1.15 {ECO:0000269\|PubMed:10679306} - Antioxidant enzyme B166 - AOEB166 - Liver tissue 2D-page spot 2D-0014IV - PLP - Peroxiredoxin V - Prx-V - Peroxisomal antioxidant enzyme - Thioredoxin peroxidase PMP20
Gene names	Prdx5
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P99029

5 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLQLGLRVLG CKASSVLRAS TCLAGRAGRK EAGWECGGAR SFSSSAVTMA PIKVGDAIPS
        70         80         90        100        110        120
VEVFEGEPGK KVNLAELFKG KKGVLFGVPG AFTPGCSKTH LPGFVEQAGA LKAKGAQVVA
       130        140        150        160        170        180
CLSVNDVFVI EEWGRAHQAE GKVRLLADPT GAFGKATDLL LDDSLVSLFG NRRLKRFSMV
       190        200        210
IDNGIVKALN VEPDGTGLTC SLAPNILSQL

Isoforms

- Isoform Cytoplasmic+peroxisomal of Peroxiredoxin-5, mitochondrial

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P99029-49-unknown	MAPIKV...	49	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P99029-49-unknown	MAPIKV...	49	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86154
P99029-49-unknown	MAPIKV...	49	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P99029-64-unknown	FEGEPG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31449
P99029-64-unknown	FEGEPG...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt136608
P99029-160-unknown	LLDDSL...	160	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30380
P99029-160-unknown	LLDDSL...	160	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143079
P99029-164-unknown	SLVSLF...	164	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29110
P99029-164-unknown	SLVSLF...	164	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143289
P99029-166-unknown	VSLFGN...	166	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30382
P99029-166-unknown	VSLFGN...	166	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143384

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PSVEVF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31449
...KATDLL	159	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30380
...KATDLL	159	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126298
...LLLDDS	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29110
...LLLDDS	163	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126519
...LDDSLV	165	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30382
...LDDSLV	165	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126616
...ILSQL	210	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ILSQL	210	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81772

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CBPA4_MOUSE	63	VEVF.\|.FEGE	inferred from experiment	unknown	MEROPS	Fricker LD	Tanco S et al.:Characterization of the substra... (M14.017)	20385563,
CATE_MOUSE	159	TDLL.\|.LLDD	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PRDX5_MOUSE @159
CATD_MOUSE	163	LDDS.\|.SLVS	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PRDX5_MOUSE @163
CATE_MOUSE	165	DSLV.\|.VSLF	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PRDX5_MOUSE @165

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)