Q01432: AMP deaminase 3

General Information

Protein names	- AMP deaminase 3 - 3.5.4.6 - AMP deaminase isoform E - Erythrocyte AMP deaminase
Gene names	AMPD3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q01432

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 1A of AMP deaminase 3 - Isoform 1C of AMP deaminase 3 - Isoform 2 of AMP deaminase 3 - Isoform 3 of AMP deaminase 3 - Isoform 4 of AMP deaminase 3

Sequence View

        10         20         30         40         50         60
MPRQFPKLNI SEVDEQVRLL AEKVFAKVLR EEDSKDALSL FTVPEDCPIG QKEAKERELQ
        70         80         90        100        110        120
KELAEQKSVE TAKRKKSFKM IRSQSLSLQM PPQQDWKGPP AASPAMSPTT PVVTGATSLP
       130        140        150        160        170        180
TPAPYAMPEF QRVTISGDYC AGITLEDYEQ AAKSLAKALM IREKYARLAY HRFPRITSQY
       190        200        210        220        230        240
LGHPRADTAP PEEGLPDFHP PPLPQEDPYC LDDAPPNLDY LVHMQGGILF VYDNKKMLEH
       250        260        270        280        290        300
QEPHSLPYPD LETYTVDMSH ILALITDGPT KTYCHRRLNF LESKFSLHEM LNEMSEFKEL
       310        320        330        340        350        360
KSNPHRDFYN VRKVDTHIHA AACMNQKHLL RFIKHTYQTE PDRTVAEKRG RKITLRQVFD
       370        380        390        400        410        420
GLHMDPYDLT VDSLDVHAGR QTFHRFDKFN SKYNPVGASE LRDLYLKTEN YLGGEYFARM
       430        440        450        460        470        480
VKEVARELEE SKYQYSEPRL SIYGRSPEEW PNLAYWFIQH KVYSPNMRWI IQVPRIYDIF
       490        500        510        520        530        540
RSKKLLPNFG KMLENIFLPL FKATINPQDH RELHLFLKYV TGFDSVDDES KHSDHMFSDK
       550        560        570        580        590        600
SPNPDVWTSE QNPPYSYYLY YMYANIMVLN NLRRERGLST FLFRPHCGEA GSITHLVSAF
       610        620        630        640        650        660
LTADNISHGL LLKKSPVLQY LYYLAQIPIA MSPLSNNSLF LEYSKNPLRE FLHKGLHVSL
       670        680        690        700        710        720
STDDPMQFHY TKEALMEEYA IAAQVWKLST CDLCEIARNS VLQSGLSHQE KQKFLGQNYY
       730        740        750        760
KEGPEGNDIR KTNVAQIRMA FRYETLCNEL SFLSDAMKSE EITALTN         10         20         30         40         50         60
MPRQFPKLNI SEVDEQVRLL AEKVFAKVLR EEDSKDALSL FTVPEDCPIG QKEAKERELQ
        70         80         90        100        110        120
KELAEQKSVE TAKRKKSFKM IRSQSLSLQM PPQQDWKGPP AASPAMSPTT PVVTGATSLP
       130        140        150        160        170        180
TPAPYAMPEF QRVTISGDYC AGITLEDYEQ AAKSLAKALM IREKYARLAY HRFPRITSQY
       190        200        210        220        230        240
LGHPRADTAP PEEGLPDFHP PPLPQEDPYC LDDAPPNLDY LVHMQGGILF VYDNKKMLEH
       250        260        270        280        290        300
QEPHSLPYPD LETYTVDMSH ILALITDGPT KTYCHRRLNF LESKFSLHEM LNEMSEFKEL
       310        320        330        340        350        360
KSNPHRDFYN VRKVDTHIHA AACMNQKHLL RFIKHTYQTE PDRTVAEKRG RKITLRQVFD
       370        380        390        400        410        420
GLHMDPYDLT VDSLDVHAGR QTFHRFDKFN SKYNPVGASE LRDLYLKTEN YLGGEYFARM
       430        440        450        460        470        480
VKEVARELEE SKYQYSEPRL SIYGRSPEEW PNLAYWFIQH KVYSPNMRWI IQVPRIYDIF
       490        500        510        520        530        540
RSKKLLPNFG KMLENIFLPL FKATINPQDH RELHLFLKYV TGFDSVDDES KHSDHMFSDK
       550        560        570        580        590        600
SPNPDVWTSE QNPPYSYYLY YMYANIMVLN NLRRERGLST FLFRPHCGEA GSITHLVSAF
       610        620        630        640        650        660
LTADNISHGL LLKKSPVLQY LYYLAQIPIA MSPLSNNSLF LEYSKNPLRE FLHKGLHVSL
       670        680        690        700        710        720
STDDPMQFHY TKEALMEEYA IAAQVWKLST CDLCEIARNS VLQSGLSHQE KQKFLGQNYY
       730        740        750        760
KEGPEGNDIR KTNVAQIRMA FRYETLCNEL SFLSDAMKSE EITALTN         10         20         30         40         50         60
MPRQFPKLNI SEVDEQVRLL AEKVFAKVLR EEDSKDALSL FTVPEDCPIG QKEAKERELQ
        70         80         90        100        110        120
KELAEQKSVE TAKRKKSFKM IRSQSLSLQM PPQQDWKGPP AASPAMSPTT PVVTGATSLP
       130        140        150        160        170        180
TPAPYAMPEF QRVTISGDYC AGITLEDYEQ AAKSLAKALM IREKYARLAY HRFPRITSQY
       190        200        210        220        230        240
LGHPRADTAP PEEGLPDFHP PPLPQEDPYC LDDAPPNLDY LVHMQGGILF VYDNKKMLEH
       250        260        270        280        290        300
QEPHSLPYPD LETYTVDMSH ILALITDGPT KTYCHRRLNF LESKFSLHEM LNEMSEFKEL
       310        320        330        340        350        360
KSNPHRDFYN VRKVDTHIHA AACMNQKHLL RFIKHTYQTE PDRTVAEKRG RKITLRQVFD
       370        380        390        400        410        420
GLHMDPYDLT VDSLDVHAGR QTFHRFDKFN SKYNPVGASE LRDLYLKTEN YLGGEYFARM
       430        440        450        460        470        480
VKEVARELEE SKYQYSEPRL SIYGRSPEEW PNLAYWFIQH KVYSPNMRWI IQVPRIYDIF
       490        500        510        520        530        540
RSKKLLPNFG KMLENIFLPL FKATINPQDH RELHLFLKYV TGFDSVDDES KHSDHMFSDK
       550        560        570        580        590        600
SPNPDVWTSE QNPPYSYYLY YMYANIMVLN NLRRERGLST FLFRPHCGEA GSITHLVSAF
       610        620        630        640        650        660
LTADNISHGL LLKKSPVLQY LYYLAQIPIA MSPLSNNSLF LEYSKNPLRE FLHKGLHVSL
       670        680        690        700        710        720
STDDPMQFHY TKEALMEEYA IAAQVWKLST CDLCEIARNS VLQSGLSHQE KQKFLGQNYY
       730        740        750        760
KEGPEGNDIR KTNVAQIRMA FRYETLCNEL SFLSDAMKSE EITALTN         10         20         30         40         50         60
MPRQFPKLNI SEVDEQVRLL AEKVFAKVLR EEDSKDALSL FTVPEDCPIG QKEAKERELQ
        70         80         90        100        110        120
KELAEQKSVE TAKRKKSFKM IRSQSLSLQM PPQQDWKGPP AASPAMSPTT PVVTGATSLP
       130        140        150        160        170        180
TPAPYAMPEF QRVTISGDYC AGITLEDYEQ AAKSLAKALM IREKYARLAY HRFPRITSQY
       190        200        210        220        230        240
LGHPRADTAP PEEGLPDFHP PPLPQEDPYC LDDAPPNLDY LVHMQGGILF VYDNKKMLEH
       250        260        270        280        290        300
QEPHSLPYPD LETYTVDMSH ILALITDGPT KTYCHRRLNF LESKFSLHEM LNEMSEFKEL
       310        320        330        340        350        360
KSNPHRDFYN VRKVDTHIHA AACMNQKHLL RFIKHTYQTE PDRTVAEKRG RKITLRQVFD
       370        380        390        400        410        420
GLHMDPYDLT VDSLDVHAGR QTFHRFDKFN SKYNPVGASE LRDLYLKTEN YLGGEYFARM
       430        440        450        460        470        480
VKEVARELEE SKYQYSEPRL SIYGRSPEEW PNLAYWFIQH KVYSPNMRWI IQVPRIYDIF
       490        500        510        520        530        540
RSKKLLPNFG KMLENIFLPL FKATINPQDH RELHLFLKYV TGFDSVDDES KHSDHMFSDK
       550        560        570        580        590        600
SPNPDVWTSE QNPPYSYYLY YMYANIMVLN NLRRERGLST FLFRPHCGEA GSITHLVSAF
       610        620        630        640        650        660
LTADNISHGL LLKKSPVLQY LYYLAQIPIA MSPLSNNSLF LEYSKNPLRE FLHKGLHVSL
       670        680        690        700        710        720
STDDPMQFHY TKEALMEEYA IAAQVWKLST CDLCEIARNS VLQSGLSHQE KQKFLGQNYY
       730        740        750        760
KEGPEGNDIR KTNVAQIRMA FRYETLCNEL SFLSDAMKSE EITALTN         10         20         30         40         50         60
MPRQFPKLNI SEVDEQVRLL AEKVFAKVLR EEDSKDALSL FTVPEDCPIG QKEAKERELQ
        70         80         90        100        110        120
KELAEQKSVE TAKRKKSFKM IRSQSLSLQM PPQQDWKGPP AASPAMSPTT PVVTGATSLP
       130        140        150        160        170        180
TPAPYAMPEF QRVTISGDYC AGITLEDYEQ AAKSLAKALM IREKYARLAY HRFPRITSQY
       190        200        210        220        230        240
LGHPRADTAP PEEGLPDFHP PPLPQEDPYC LDDAPPNLDY LVHMQGGILF VYDNKKMLEH
       250        260        270        280        290        300
QEPHSLPYPD LETYTVDMSH ILALITDGPT KTYCHRRLNF LESKFSLHEM LNEMSEFKEL
       310        320        330        340        350        360
KSNPHRDFYN VRKVDTHIHA AACMNQKHLL RFIKHTYQTE PDRTVAEKRG RKITLRQVFD
       370        380        390        400        410        420
GLHMDPYDLT VDSLDVHAGR QTFHRFDKFN SKYNPVGASE LRDLYLKTEN YLGGEYFARM
       430        440        450        460        470        480
VKEVARELEE SKYQYSEPRL SIYGRSPEEW PNLAYWFIQH KVYSPNMRWI IQVPRIYDIF
       490        500        510        520        530        540
RSKKLLPNFG KMLENIFLPL FKATINPQDH RELHLFLKYV TGFDSVDDES KHSDHMFSDK
       550        560        570        580        590        600
SPNPDVWTSE QNPPYSYYLY YMYANIMVLN NLRRERGLST FLFRPHCGEA GSITHLVSAF
       610        620        630        640        650        660
LTADNISHGL LLKKSPVLQY LYYLAQIPIA MSPLSNNSLF LEYSKNPLRE FLHKGLHVSL
       670        680        690        700        710        720
STDDPMQFHY TKEALMEEYA IAAQVWKLST CDLCEIARNS VLQSGLSHQE KQKFLGQNYY
       730        740        750        760
KEGPEGNDIR KTNVAQIRMA FRYETLCNEL SFLSDAMKSE EITALTN

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q01432-1-unknown	MPRQFP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q01432-1-unknown	MPRQFP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98578
Q01432-1-unknown	MPRQFP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98580
Q01432-1-unknown	MPRQFP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98579
Q01432-1-unknown	MPRQFP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98581
Q01432-1-acetylation	MPRQFP...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q01432-1-acetylation	MPRQFP...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183001
Q01432-1-acetylation	MPRQFP...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183003
Q01432-1-acetylation	MPRQFP...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183002
Q01432-1-acetylation	MPRQFP...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183004
Q01432-160-unknown	MIREKY...	160		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66821
Q01432-160-unknown	MIREKY...	160		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt96038
Q01432-160-unknown	MIREKY...	160		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt96040
Q01432-160-unknown	MIREKY...	160		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt96039
Q01432-160-unknown	MIREKY...	160		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt96041

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPQEDP	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62435
...LPQEDP	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91995
...LPQEDP	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91996
...LPQEDP	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91998
...LPQEDP	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91997
...PLREFL	651	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62436
...PLREFL	651	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93189
...PLREFL	651	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93190
...PLREFL	651	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93191
...TALTN	767	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TALTN	767	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62439
...TALTN	767	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62438
...TALTN	767	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62437

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)