Q01523: Defensin-5
| Protein names | - Defensin-5 - Defensin, alpha 5 - HD5(20-94) - HD5(23-94) - HD5(29-94) - HD5(56-94) - HD5(63-94) |
|---|---|
| Gene names | DEFA5 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q01523 |
2
N-termini
2
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MRTIAILAAI LLVALQAQAE SLQERADEAT TQKQSGEDNQ DLAISFAGNG LSALRTSGSQ
70 80 90
ARATCYCRTG RCATRESLSG VCEISGRLYR LCCR
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q01523-63-unknown | ATCYCR... | 63 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31926 | |||
| Q01523-63-unknown | ATCYCR... | 63 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16366 | |||
| Q01523-69-unknown | TGRCAT... | 69 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31927 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GSQARA | 62 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31926 | |||
| ...GSQARA | 62 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16366 | |||
| ...TCYCRT | 68 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31927 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| TRY2_HUMAN | 62 | QARA.|.ATCY | inferred from experiment | unknown | MEROPS | Ouellette AJ | Weeks CS et al.:Matrix metalloproteinase-7 acti... (S01.258) | 16822871, |
| KLK4_HUMAN | 62 | QARA.|.ATCY | inferred from experiment | unknown | MEROPS | Nelson PS | Matsumura M et al.:Substrates of the prostate-spec... (S01.251) | 15389820, |
| TRY2_HUMAN | 68 | YCRT.|.TGRC | inferred from experiment | unknown | MEROPS | Ouellette AJ | Weeks CS et al.:Matrix metalloproteinase-7 acti... (S01.258) | 16822871, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|