Q01543: Friend leukemia integration 1 transcription factor

General Information

Protein names	- Friend leukemia integration 1 transcription factor - Proto-oncogene Fli-1 - Transcription factor ERGB
Gene names	FLI1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q01543

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Friend leukemia integration 1 transcription factor - Isoform 3 of Friend leukemia integration 1 transcription factor - Isoform 4 of Friend leukemia integration 1 transcription factor

Sequence View

        10         20         30         40         50         60
MDGTIKEALS VVSDDQSLFD SAYGAAAHLP KADMTASGSP DYGQPHKINP LPPQQEWINQ
        70         80         90        100        110        120
PVRVNVKREY DHMNGSRESP VDCSVSKCSK LVGGGESNPM NYNSYMDEKN GPPPPNMTTN
       130        140        150        160        170        180
ERRVIVPADP TLWTQEHVRQ WLEWAIKEYS LMEIDTSFFQ NMDGKELCKM NKEDFLRATT
       190        200        210        220        230        240
LYNTEVLLSH LSYLRESSLL AYNTTSHTDQ SSRLSVKEDP SYDSVRRGAW GNNMNSGLNK
       250        260        270        280        290        300
SPPLGGAQTI SKNTEQRPQP DPYQILGPTS SRLANPGSGQ IQLWQFLLEL LSDSANASCI
       310        320        330        340        350        360
TWEGTNGEFK MTDPDEVARR WGERKSKPNM NYDKLSRALR YYYDKNIMTK VHGKRYAYKF
       370        380        390        400        410        420
DFHGIAQALQ PHPTESSMYK YPSDISYMPS YHAHQQKVNF VPPHPSSMPV TSSSFFGAAS
       430        440        450
QYWTSPTGGI YPNPNVPRHP NTHVPSHLGS YY         10         20         30         40         50         60
MDGTIKEALS VVSDDQSLFD SAYGAAAHLP KADMTASGSP DYGQPHKINP LPPQQEWINQ
        70         80         90        100        110        120
PVRVNVKREY DHMNGSRESP VDCSVSKCSK LVGGGESNPM NYNSYMDEKN GPPPPNMTTN
       130        140        150        160        170        180
ERRVIVPADP TLWTQEHVRQ WLEWAIKEYS LMEIDTSFFQ NMDGKELCKM NKEDFLRATT
       190        200        210        220        230        240
LYNTEVLLSH LSYLRESSLL AYNTTSHTDQ SSRLSVKEDP SYDSVRRGAW GNNMNSGLNK
       250        260        270        280        290        300
SPPLGGAQTI SKNTEQRPQP DPYQILGPTS SRLANPGSGQ IQLWQFLLEL LSDSANASCI
       310        320        330        340        350        360
TWEGTNGEFK MTDPDEVARR WGERKSKPNM NYDKLSRALR YYYDKNIMTK VHGKRYAYKF
       370        380        390        400        410        420
DFHGIAQALQ PHPTESSMYK YPSDISYMPS YHAHQQKVNF VPPHPSSMPV TSSSFFGAAS
       430        440        450
QYWTSPTGGI YPNPNVPRHP NTHVPSHLGS YY         10         20         30         40         50         60
MDGTIKEALS VVSDDQSLFD SAYGAAAHLP KADMTASGSP DYGQPHKINP LPPQQEWINQ
        70         80         90        100        110        120
PVRVNVKREY DHMNGSRESP VDCSVSKCSK LVGGGESNPM NYNSYMDEKN GPPPPNMTTN
       130        140        150        160        170        180
ERRVIVPADP TLWTQEHVRQ WLEWAIKEYS LMEIDTSFFQ NMDGKELCKM NKEDFLRATT
       190        200        210        220        230        240
LYNTEVLLSH LSYLRESSLL AYNTTSHTDQ SSRLSVKEDP SYDSVRRGAW GNNMNSGLNK
       250        260        270        280        290        300
SPPLGGAQTI SKNTEQRPQP DPYQILGPTS SRLANPGSGQ IQLWQFLLEL LSDSANASCI
       310        320        330        340        350        360
TWEGTNGEFK MTDPDEVARR WGERKSKPNM NYDKLSRALR YYYDKNIMTK VHGKRYAYKF
       370        380        390        400        410        420
DFHGIAQALQ PHPTESSMYK YPSDISYMPS YHAHQQKVNF VPPHPSSMPV TSSSFFGAAS
       430        440        450
QYWTSPTGGI YPNPNVPRHP NTHVPSHLGS YY

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q01543-1-unknown	MDGTIK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q01543-21-	SAYGAA...	21		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q01543-21-	SAYGAA...	21		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q01543-21-	SAYGAA...	21		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q01543-21-	SAYGAA...	21		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q01543-21-unknown	SAYGAA...	21		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q01543-34-unknown	MTASGS...	34	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75249

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LGSYY	452	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LGSYY	452	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70868
...LGSYY	452	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70866
...LGSYY	452	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70867

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)