Q03267: DNA-binding protein Ikaros

General Information

Protein names	- DNA-binding protein Ikaros - Ikaros family zinc finger protein 1 - Lymphoid transcription factor LyF-1
Gene names	Ikzf1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q03267

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform I of DNA-binding protein Ikaros - Isoform II of DNA-binding protein Ikaros - Isoform III of DNA-binding protein Ikaros - Isoform IV of DNA-binding protein Ikaros - Isoform V of DNA-binding protein Ikaros

Sequence View

        10         20         30         40         50         60
MDVDEGQDMS QVSGKESPPV SDTPDEGDEP MPVPEDLSTT SGAQQNSKSD RGMGSNVKVE
        70         80         90        100        110        120
TQSDEENGRA CEMNGEECAE DLRMLDASGE KMNGSHRDQG SSALSGVGGI RLPNGKLKCD
       130        140        150        160        170        180
ICGIVCIGPN VLMVHKRSHT ERPFQCNQCG ASFTQKGNLL RHIKLHSGEK PFKCHLCNYA
       190        200        210        220        230        240
CRRRDALTGH LRTHSVGKPH KCGYCGRSYK QRSSLEEHKE RCHNYLESMG LPGVCPVIKE
       250        260        270        280        290        300
ETNHNEMAED LCKIGAERSL VLDRLASNVA KRKSSMPQKF LGDKCLSDMP YDSANYEKED
       310        320        330        340        350        360
MMTSHVMDQA INNAINYLGA ESLRPLVQTP PGSSEVVPVI SSMYQLHKPP SDGPPRSNHS
       370        380        390        400        410        420
AQDAVDNLLL LSKAKSVSSE REASPSNSCQ DSTDTESNAE EQRSGLIYLT NHINPHARNG
       430        440        450        460        470        480
LALKEEQRAY EVLRAASENS QDAFRVVSTS GEQLKVYKCE HCRVLFLDHV MYTIHMGCHG
       490        500        510
CHGFRDPFEC NMCGYHSQDR YEFSSHITRG EHRYHLS         10         20         30         40         50         60
MDVDEGQDMS QVSGKESPPV SDTPDEGDEP MPVPEDLSTT SGAQQNSKSD RGMGSNVKVE
        70         80         90        100        110        120
TQSDEENGRA CEMNGEECAE DLRMLDASGE KMNGSHRDQG SSALSGVGGI RLPNGKLKCD
       130        140        150        160        170        180
ICGIVCIGPN VLMVHKRSHT ERPFQCNQCG ASFTQKGNLL RHIKLHSGEK PFKCHLCNYA
       190        200        210        220        230        240
CRRRDALTGH LRTHSVGKPH KCGYCGRSYK QRSSLEEHKE RCHNYLESMG LPGVCPVIKE
       250        260        270        280        290        300
ETNHNEMAED LCKIGAERSL VLDRLASNVA KRKSSMPQKF LGDKCLSDMP YDSANYEKED
       310        320        330        340        350        360
MMTSHVMDQA INNAINYLGA ESLRPLVQTP PGSSEVVPVI SSMYQLHKPP SDGPPRSNHS
       370        380        390        400        410        420
AQDAVDNLLL LSKAKSVSSE REASPSNSCQ DSTDTESNAE EQRSGLIYLT NHINPHARNG
       430        440        450        460        470        480
LALKEEQRAY EVLRAASENS QDAFRVVSTS GEQLKVYKCE HCRVLFLDHV MYTIHMGCHG
       490        500        510
CHGFRDPFEC NMCGYHSQDR YEFSSHITRG EHRYHLS         10         20         30         40         50         60
MDVDEGQDMS QVSGKESPPV SDTPDEGDEP MPVPEDLSTT SGAQQNSKSD RGMGSNVKVE
        70         80         90        100        110        120
TQSDEENGRA CEMNGEECAE DLRMLDASGE KMNGSHRDQG SSALSGVGGI RLPNGKLKCD
       130        140        150        160        170        180
ICGIVCIGPN VLMVHKRSHT ERPFQCNQCG ASFTQKGNLL RHIKLHSGEK PFKCHLCNYA
       190        200        210        220        230        240
CRRRDALTGH LRTHSVGKPH KCGYCGRSYK QRSSLEEHKE RCHNYLESMG LPGVCPVIKE
       250        260        270        280        290        300
ETNHNEMAED LCKIGAERSL VLDRLASNVA KRKSSMPQKF LGDKCLSDMP YDSANYEKED
       310        320        330        340        350        360
MMTSHVMDQA INNAINYLGA ESLRPLVQTP PGSSEVVPVI SSMYQLHKPP SDGPPRSNHS
       370        380        390        400        410        420
AQDAVDNLLL LSKAKSVSSE REASPSNSCQ DSTDTESNAE EQRSGLIYLT NHINPHARNG
       430        440        450        460        470        480
LALKEEQRAY EVLRAASENS QDAFRVVSTS GEQLKVYKCE HCRVLFLDHV MYTIHMGCHG
       490        500        510
CHGFRDPFEC NMCGYHSQDR YEFSSHITRG EHRYHLS         10         20         30         40         50         60
MDVDEGQDMS QVSGKESPPV SDTPDEGDEP MPVPEDLSTT SGAQQNSKSD RGMGSNVKVE
        70         80         90        100        110        120
TQSDEENGRA CEMNGEECAE DLRMLDASGE KMNGSHRDQG SSALSGVGGI RLPNGKLKCD
       130        140        150        160        170        180
ICGIVCIGPN VLMVHKRSHT ERPFQCNQCG ASFTQKGNLL RHIKLHSGEK PFKCHLCNYA
       190        200        210        220        230        240
CRRRDALTGH LRTHSVGKPH KCGYCGRSYK QRSSLEEHKE RCHNYLESMG LPGVCPVIKE
       250        260        270        280        290        300
ETNHNEMAED LCKIGAERSL VLDRLASNVA KRKSSMPQKF LGDKCLSDMP YDSANYEKED
       310        320        330        340        350        360
MMTSHVMDQA INNAINYLGA ESLRPLVQTP PGSSEVVPVI SSMYQLHKPP SDGPPRSNHS
       370        380        390        400        410        420
AQDAVDNLLL LSKAKSVSSE REASPSNSCQ DSTDTESNAE EQRSGLIYLT NHINPHARNG
       430        440        450        460        470        480
LALKEEQRAY EVLRAASENS QDAFRVVSTS GEQLKVYKCE HCRVLFLDHV MYTIHMGCHG
       490        500        510
CHGFRDPFEC NMCGYHSQDR YEFSSHITRG EHRYHLS         10         20         30         40         50         60
MDVDEGQDMS QVSGKESPPV SDTPDEGDEP MPVPEDLSTT SGAQQNSKSD RGMGSNVKVE
        70         80         90        100        110        120
TQSDEENGRA CEMNGEECAE DLRMLDASGE KMNGSHRDQG SSALSGVGGI RLPNGKLKCD
       130        140        150        160        170        180
ICGIVCIGPN VLMVHKRSHT ERPFQCNQCG ASFTQKGNLL RHIKLHSGEK PFKCHLCNYA
       190        200        210        220        230        240
CRRRDALTGH LRTHSVGKPH KCGYCGRSYK QRSSLEEHKE RCHNYLESMG LPGVCPVIKE
       250        260        270        280        290        300
ETNHNEMAED LCKIGAERSL VLDRLASNVA KRKSSMPQKF LGDKCLSDMP YDSANYEKED
       310        320        330        340        350        360
MMTSHVMDQA INNAINYLGA ESLRPLVQTP PGSSEVVPVI SSMYQLHKPP SDGPPRSNHS
       370        380        390        400        410        420
AQDAVDNLLL LSKAKSVSSE REASPSNSCQ DSTDTESNAE EQRSGLIYLT NHINPHARNG
       430        440        450        460        470        480
LALKEEQRAY EVLRAASENS QDAFRVVSTS GEQLKVYKCE HCRVLFLDHV MYTIHMGCHG
       490        500        510
CHGFRDPFEC NMCGYHSQDR YEFSSHITRG EHRYHLS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q03267-1-unknown	MDVDEG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q03267-1-unknown	MDVDEG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77696
Q03267-1-unknown	MDVDEG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77697
Q03267-1-unknown	MDVDEG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77698
Q03267-1-unknown	MDVDEG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77699
Q03267-1-unknown	MDVDEG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77700
Q03267-74-unknown	NGEECA...	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32612
Q03267-74-unknown	NGEECA...	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140887
Q03267-74-unknown	NGEECA...	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142000

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RACEMN	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32612
...RACEMN	73	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124028
...RACEMN	73	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125181
...RYHLS	517	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RYHLS	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73314
...RYHLS	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73315
...RYHLS	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73316
...RYHLS	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73317
...RYHLS	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73318

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAC_MOUSE	73	CEMN.\|.NGEE	inferred from experiment	unknown	MEROPS	Bird PI	Kaiserman D et al.:Structure of granzyme C reveals... (S01.137)	19299505,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)