Q06335: Amyloid-like protein 2

General Information

Protein names	- Amyloid-like protein 2 - APLP-2 - CDEI box-binding protein - CDEBP
Gene names	Aplp2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q06335

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAATGTAAAA ATGKLLVLLL LGLTAPAAAL AGYIEALAAN AGTGFAVAEP QIAMFCGKLN
        70         80         90        100        110        120
MHVNIQTGKW EPDPTGTKSC LGTKEEVLQY CQEIYPELQI TNVMEANQPV NIDSWCRRDK
       130        140        150        160        170        180
RQCKSHIVIP FKCLVGEFVS DVLLVPDNCQ FFHQERMEVC EKHQRWHTLV KEACLTEGLT
       190        200        210        220        230        240
LYSYGMLLPC GVDQFHGTEY VCCPQTKTVD SDSTMSKEEE EEEEDEEDEE EDYDLDKSEF
       250        260        270        280        290        300
PTEADLEDFT EAAADEEEED EEEGEEVVED RDYYYDPFKG DDYNEENPTE PSSEGTISDK
       310        320        330        340        350        360
EIVHDVKVPP TPLPTNDVDV YFETSADDNE HARFQKAKEQ LEIRHRNRMD RVKKEWEEAE
       370        380        390        400        410        420
LQAKNLPKTE RQTLIQHFQA MVKALEKEAA SEKQQLVETH LARVEAMLND RRRIALENYL
       430        440        450        460        470        480
AALQSDPPRP HRILQALRRY VRAENKDRLH TIRHYQHVLA VDPEKAAQMK SQVMTHLHVI
       490        500        510        520        530        540
EERRNQSLSL LYKVPYVAQE IQEEIDELLQ EQRADMDQFT SSISENPVDV RVSSEESEEI
       550        560        570        580        590        600
PPFHPLHPFP SLSENEDTQP ELYHPMKKGS GMAEQDGGLI GAEEKVINSK NKMDENMVID
       610        620        630        640        650        660
ETLDVKEMIF NAERVGGLEE EPESVGPLRE DFSLSSNALI GLLVIAVAIA TVIVISLVML
       670        680        690        700
RKRQYGTISH GIVEVDPMLT PEERHLNKMQ NHGYENPTYK YLEQMQI

Isoforms

- Isoform 2 of Amyloid-like protein 2

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q06335-1-unknown	MAATGT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67239
Q06335-32-unknown	GYIEAL...	32	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q06335-32-unknown	GYIEAL...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114921
Q06335-385-unknown	LEKEAA...	385	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33897
Q06335-385-unknown	LEKEAA...	385	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151739
Q06335-469-unknown	MKSQVM...	469	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33899
Q06335-469-unknown	MKSQVM...	469	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt153068

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AMVKAL	384	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33897
...AMVKAL	384	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135144
...EKAAQM	468	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33899
...EKAAQM	468	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136493
...EQMQI	707	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EQMQI	707	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62857

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	384	VKAL.\|.LEKE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	468	AAQM.\|.MKSQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)