Q07866: Kinesin light chain 1
| Protein names | - Kinesin light chain 1 - KLC 1 |
|---|---|
| Gene names | KLC1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q07866 |
4
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
Isoforms
- Isoform C of Kinesin light chain 1 - Isoform G of Kinesin light chain 1 - Isoform J of Kinesin light chain 1 - Isoform K of Kinesin light chain 1 - Isoform N of Kinesin light chain 1 - Isoform P of Kinesin light chain 1 - Isoform S of Kinesin light chain 1 - Isoform I of Kinesin light chain 1 - Isoform D of Kinesin light chain 1Sequence View
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
10 20 30 40 50 60
MYDNMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD
70 80 90 100 110 120
ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQKLRAQV RRLCQENQWL
130 140 150 160 170 180
RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDTD STKEPLDDLF
190 200 210 220 230 240
PNDEDDPGQG IQQQHSSAAA AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL
250 260 270 280 290 300
EDLEKTSGHD HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350 360
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY
370 380 390 400 410 420
YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD
430 440 450 460 470 480
DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF
490 500 510 520 530 540
EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE
550 560 570
EVSMSVEWNG GVSGRASFCG KRQQQQWPGR RHR
Protein Neighborhood
Domains & Features
4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q07866-1-unknown | MYDNMS... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q07866-1-unknown | MYDNMS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79044 | |||
| Q07866-1-unknown | MYDNMS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79045 | |||
| Q07866-1-unknown | MYDNMS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79046 | |||
| Q07866-1-unknown | MYDNMS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79047 | |||
| Q07866-1-unknown | MYDNMS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79048 | |||
| Q07866-1-unknown | MYDNMS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79049 | |||
| Q07866-1-unknown | MYDNMS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79050 | |||
| Q07866-1-unknown | MYDNMS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt79051 | |||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| Q07866-5-unknown | MSTMVY... | 5 | unknown | Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
| Q07866-5-unknown | MSTMVY... | 5 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159846 | |||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159847 | |||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159848 | |||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159849 | |||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159850 | |||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159851 | |||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159852 | |||
| Q07866-5-unknown | MSTMVY... | 5 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159853 | |||
| Q07866-9-unknown | VYIKED... | 9 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164820 | |||
| Q07866-9-unknown | VYIKED... | 9 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164821 | |||
| Q07866-9-unknown | VYIKED... | 9 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164822 | |||
| Q07866-9-unknown | VYIKED... | 9 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164823 | |||
| Q07866-9-unknown | VYIKED... | 9 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164824 | |||
| Q07866-9-unknown | VYIKED... | 9 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164825 | |||
| Q07866-9-unknown | VYIKED... | 9 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164826 | |||
| Q07866-9-unknown | VYIKED... | 9 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt164827 | |||
| Q07866-9- | VYIKED... | 9 | Subtiligase Based Positive Selection | Wells | DB_Untreated | 23264352 | |||
| Q07866-9- | VYIKED... | 9 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
| Q07866-9- | VYIKED... | 9 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
| Q07866-9- | VYIKED... | 9 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
| Q07866-9- | VYIKED... | 9 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GRRHR | 573 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...GRRHR | 573 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt74663 | |||
| ...GRRHR | 573 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt74665 | |||
| ...GRRHR | 573 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt74669 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|