Q08188: Protein-glutamine gamma-glutamyltransferase E
Protein names | - Protein-glutamine gamma-glutamyltransferase E - 2.3.2.13 {ECO:0000269|PubMed:11980702, ECO:0000269|PubMed:12679341, ECO:0000269|PubMed:27866708} - Transglutaminase E - TG(E) - TGE - TGase E - Transglutaminase-3 - TGase-3 - Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain - Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain |
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Gene names | TGM3 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q08188 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAALGVQSIN WQTAFNRQAH HTDKFSSQEL ILRRGQNFQV LMIMNKGLGS NERLEFIVST
70 80 90 100 110 120
GPYPSESAMT KAVFPLSNGS SGGWSAVLQA SNGNTLTISI SSPASAPIGR YTMALQIFSQ
130 140 150 160 170 180
GGISSVKLGT FILLFNPWLN VDSVFMGNHA EREEYVQEDA GIIFVGSTNR IGMIGWNFGQ
190 200 210 220 230 240
FEEDILSICL SILDRSLNFR RDAATDVASR NDPKYVGRVL SAMINSNDDN GVLAGNWSGT
250 260 270 280 290 300
YTGGRDPRSW NGSVEILKNW KKSGFSPVRY GQCWVFAGTL NTALRSLGIP SRVITNFNSA
310 320 330 340 350 360
HDTDRNLSVD VYYDPMGNPL DKGSDSVWNF HVWNEGWFVR SDLGPSYGGW QVLDATPQER
370 380 390 400 410 420
SQGVFQCGPA SVIGVREGDV QLNFDMPFIF AEVNADRITW LYDNTTGKQW KNSVNSHTIG
430 440 450 460 470 480
RYISTKAVGS NARMDVTDKY KYPEGSDQER QVFQKALGKL KPNTPFAATS SMGLETEEQE
490 500 510 520 530 540
PSIIGKLKVA GMLAVGKEVN LVLLLKNLSR DTKTVTVNMT AWTIIYNGTL VHEVWKDSAT
550 560 570 580 590 600
MSLDPEEEAE HPIKISYAQY EKYLKSDNMI RITAVCKVPD ESEVVVERDI ILDNPTLTLE
610 620 630 640 650 660
VLNEARVRKP VNVQMLFSNP LDEPVRDCVL MVEGSGLLLG NLKIDVPTLG PKEGSRVRFD
670 680 690
ILPSRSGTKQ LLADFSCNKF PAIKAMLSID VAE
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q08188-2-unknown | MAALGV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q08188-2-Acetylation | AALGVQ... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q08188-468-unknown | ATSSMG... | 468 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q08188-468-unknown | ATSSMG... | 468 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6251 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...NTPFAA | 467 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...NTPFAA | 467 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6251 | |||
...IDVAE | 693 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATL1_HUMAN | 467 | PFAA.|.ATSS | inferred from experiment | unknown | MEROPS | Zeeuwen PL | Cheng T et al.:Cystatin M/E is a high affinity... (C01.032) | 16565075, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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