Q08380: Galectin-3-binding protein

General Information

Protein names	- Galectin-3-binding protein - Basement membrane autoantigen p105 - Lectin galactoside-binding soluble 3-binding protein - Mac-2-binding protein - MAC2BP - Mac-2 BP - Tumor-associated antigen 90K
Gene names	LGALS3BP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q08380

5 N-termini

8 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTPPRLFWVW LLVAGTQGVN DGDMRLADGG ATNQGRVEIF YRGQWGTVCD NLWDLTDASV
        70         80         90        100        110        120
VCRALGFENA TQALGRAAFG QGSGPIMLDE VQCTGTEASL ADCKSLGWLK SNCRHERDAG
       130        140        150        160        170        180
VVCTNETRST HTLDLSRELS EALGQIFDSQ RGCDLSISVN VQGEDALGFC GHTVILTANL
       190        200        210        220        230        240
EAQALWKEPG SNVTMSVDAE CVPMVRDLLR YFYSRRIDIT LSSVKCFHKL ASAYGARQLQ
       250        260        270        280        290        300
GYCASLFAIL LPQDPSFQMP LDLYAYAVAT GDALLEKLCL QFLAWNFEAL TQAEAWPSVP
       310        320        330        340        350        360
TDLLQLLLPR SDLAVPSELA LLKAVDTWSW GERASHEEVE GLVEKIRFPM MLPEELFELQ
       370        380        390        400        410        420
FNLSLYWSHE ALFQKKTLQA LEFHTVPFQL LARYKGLNLT EDTYKPRIYT SPTWSAFVTD
       430        440        450        460        470        480
SSWSARKSQL VYQSRRGPLV KYSSDYFQAP SDYRYYPYQS FQTPQHPSFL FQDKRVSWSL
       490        500        510        520        530        540
VYLPTIQSCW NYGFSCSSDE LPVLGLTKSG GSDRTIAYEN KALMLCEGLF VADVTDFEGW
       550        560        570        580
KAAIPSALDT NSSKSTSSFP CPAGHFNGFR TVIRPFYLTN SSGVD

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 8 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
Q08380-19-unknown	VNDGDM...	19	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q08380-437-unknown	GPLVKY...	437	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19372
Q08380-442-unknown	YSSDYF...	442		unknown		Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
Q08380-443-unknown	SSDYFQ...	443		unknown		Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
Q08380-453-unknown	YRYYPY...	453	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24779

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GPIMLD	88	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468586
...MVRDLL	208	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465380
...VRDLLR	209	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468774
...RDLLRY	210	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465729
...PSFQMP	259	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467211
...YQSRRG	436	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19372
...QAPSDY	452	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24779
...SSGVD	585	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	436	SRRG.\|.GPLV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MMP7_HUMAN	452	PSDY.\|.YRYY	inferred from experiment	unknown	MEROPS	Laferte S	Ulmer TA et al.:The tumor-associated antigen 90... (M10.008)	19665518,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)