Q08945: FACT complex subunit SSRP1

General Information

Protein names	- FACT complex subunit SSRP1 - Chromatin-specific transcription elongation factor 80 kDa subunit - Facilitates chromatin transcription complex 80 kDa subunit - FACT 80 kDa subunit - FACTp80 - Facilitates chromatin transcription complex subunit SSRP1 - Recombination signal sequence recognition protein 1 - Structure-specific recognition protein 1 - hSSRP1 - T160
Gene names	SSRP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q08945

6 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAETLEFNDV YQEVKGSMND GRLRLSRQGI IFKNSKTGKV DNIQAGELTE GIWRRVALGH
        70         80         90        100        110        120
GLKLLTKNGH VYKYDGFRES EFEKLSDFFK THYRLELMEK DLCVKGWNWG TVKFGGQLLS
       130        140        150        160        170        180
FDIGDQPVFE IPLSNVSQCT TGKNEVTLEF HQNDDAEVSL MEVRFYVPPT QEDGVDPVEA
       190        200        210        220        230        240
FAQNVLSKAD VIQATGDAIC IFRELQCLTP RGRYDIRIYP TFLHLHGKTF DYKIPYTTVL
       250        260        270        280        290        300
RLFLLPHKDQ RQMFFVISLD PPIKQGQTRY HFLILLFSKD EDISLTLNMN EEEVEKRFEG
       310        320        330        340        350        360
RLTKNMSGSL YEMVSRVMKA LVNRKITVPG NFQGHSGAQC ITCSYKASSG LLYPLERGFI
       370        380        390        400        410        420
YVHKPPVHIR FDEISFVNFA RGTTTTRSFD FEIETKQGTQ YTFSSIEREE YGKLFDFVNA
       430        440        450        460        470        480
KKLNIKNRGL KEGMNPSYDE YADSDEDQHD AYLERMKEEG KIREENANDS SDDSGEETDE
       490        500        510        520        530        540
SFNPGEEEED VAEEFDSNAS ASSSSNEGDS DRDEKKRKQL KKAKMAKDRK SRKKPVEVKK
       550        560        570        580        590        600
GKDPNAPKRP MSAYMLWLNA SREKIKSDHP GISITDLSKK AGEIWKGMSK EKKEEWDRKA
       610        620        630        640        650        660
EDARRDYEKA MKEYEGGRGE SSKRDKSKKK KKVKVKMEKK STPSRGSSSK SSSRQLSESF
       670        680        690        700
KSKEFVSSDE SSSGENKSKK KRRRSEDSEE EELASTPPSS EDSASGSDE

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q08945-2-unknown	MAETLE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q08945-2-Acetylation	AETLEF...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q08945-2-Acetylation	AETLEF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q08945-2-Acetylation	AETLEF...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q08945-2-Acetylation	AETLEF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q08945-98-unknown	MEKDLC...	98		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000431154
Q08945-98-unknown	MEKDLC...	98		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000434546
Q08945-165-	FYVPPT...	165			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q08945-174-	GVDPVE...	174			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q08945-451-unknown	AYLERM...	451		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2124
Q08945-451-unknown	AYLERM...	451		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC2953

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HKDQRQ	251	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434546
...LTLNMN	289	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431154
...EDQHDA	450	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2124
...EDQHDA	450	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2953
...SGSDE	709	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	450	QHDA.\|.AYLE	inferred from experiment	unknown	MEROPS	Lu H	Landais I et al.:Coupling caspase cleavage and u... (C14.003)	16498457,
CASP7_HUMAN	450	QHDA.\|.AYLE	inferred from experiment	unknown	MEROPS	Lu H	Landais I et al.:Coupling caspase cleavage and u... (C14.003)	16498457,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)