Q13057: Bifunctional coenzyme A synthase

General Information

Protein names	- Bifunctional coenzyme A synthase - CoA synthase - NBP - POV-2 - Phosphopantetheine adenylyltransferase - 2.7.7.3 - Dephospho-CoA pyrophosphorylase - Pantetheine-phosphate adenylyltransferase - PPAT - Dephospho-CoA kinase - DPCK - 2.7.1.24 - Dephosphocoenzyme A kinase - DPCOAK
Gene names	COASY
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13057

4 N-termini

8 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVFRSGLLV LTTPLASLAP RLASILTSAA RLVNHTLYVH LQPGMSLEGP AQPQSSPVQA
        70         80         90        100        110        120
TFEVLDFITH LYAGADVHRH LDVRILLTNI RTKSTFLPPL PTSVQNLAHP PEVVLTDFQT
       130        140        150        160        170        180
LDGSQYNPVK QQLVRYATSC YSCCPRLASV LLYSDYGIGE VPVEPLDVPL PSTIRPASPV
       190        200        210        220        230        240
AGSPKQPVRG YYRGAVGGTF DRLHNAHKVL LSVACILAQE QLVVGVADKD LLKSKLLPEL
       250        260        270        280        290        300
LQPYTERVEH LSEFLVDIKP SLTFDVIPLL DPYGPAGSDP SLEFLVVSEE TYRGGMAINR
       310        320        330        340        350        360
FRLENDLEEL ALYQIQLLKD LRHTENEEDK VSSSSFRQRM LGNLLRPPYE RPELPTCLYV
       370        380        390        400        410        420
IGLTGISGSG KSSIAQRLKG LGAFVIDSDH LGHRAYAPGG PAYQPVVEAF GTDILHKDGI
       430        440        450        460        470        480
INRKVLGSRV FGNKKQLKIL TDIMWPIIAK LAREEMDRAV AEGKRVCVID AAVLLEAGWQ
       490        500        510        520        530        540
NLVHEVWTAV IPETEAVRRI VERDGLSEAA AQSRLQSQMS GQQLVEQSHV VLSTLWEPHI
       550        560
TQRQVEKAWA LLQKRIPKTH QALD

Isoforms

- Isoform 2 of Bifunctional coenzyme A synthase

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

4 N-termini - 8 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q13057-1-unknown	MAVFRS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13057-1-unknown	MAVFRS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103284
Q13057-296-unknown	MAINRF...	296	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000467687
Q13057-296-unknown	MAINRF...	296	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000407740
Q13057-296-unknown	MAINRF...	296	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt198813
Q13057-504-unknown	DGLSEA...	504	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183037
Q13057-504-	DGLSEA...	504		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LDFITH	69	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467519
...LDFITH	69	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154022
...LLTNIR	90	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467174
...LLTNIR	90	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154278
...TFLPPL	99	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468755
...TFLPPL	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154353
...CCPRLA	147	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468583
...CCPRLA	147	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154925
...LPSTIR	174	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467322
...LPSTIR	174	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155321
...CILAQE	219	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466838
...CILAQE	219	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155800
...VVEAFG	410	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000467687
...HQALD	564	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HQALD	564	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66917

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)