Q13094: Lymphocyte cytosolic protein 2

General Information

Protein names	- Lymphocyte cytosolic protein 2 - SH2 domain-containing leukocyte protein of 76 kDa - SLP-76 tyrosine phosphoprotein - SLP76
Gene names	LCP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13094

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALRNVPFRS EVLGWDPDSL ADYFKKLNYK DCEKAVKKYH IDGARFLNLT ENDIQKFPKL
        70         80         90        100        110        120
RVPILSKLSQ EINKNEERRS IFTRKPQVPR FPEETESHEE DNGGWSSFEE DDYESPNDDQ
       130        140        150        160        170        180
DGEDDGDYES PNEEEEAPVE DDADYEPPPS NDEEALQNSI LPAKPFPNSN SMYIDRPPSG
       190        200        210        220        230        240
KTPQQPPVPP QRPMAALPPP PAGRNHSPLP PPQTNHEEPS RSRNHKTAKL PAPSIDRSTK
       250        260        270        280        290        300
PPLDRSLAPF DREPFTLGKK PPFSDKPSIP AGRSLGEHLP KIQKPPLPPT TERHERSSPL
       310        320        330        340        350        360
PGKKPPVPKH GWGPDRREND EDDVHQRPLP QPALLPMSSN TFPSRSTKPS PMNPLPSSHM
       370        380        390        400        410        420
PGAFSESNSS FPQSASLPPY FSQGPSNRPP IRAEGRNFPL PLPNKPRPPS PAEEENSLNE
       430        440        450        460        470        480
EWYVSYITRP EAEAALRKIN QDGTFLVRDS SKKTTTNPYV LMVLYKDKVY NIQIRYQKES
       490        500        510        520        530
QVYLLGTGLR GKEDFLSVSD IIDYFRKMPL LLIDGKNRGS RYQCTLTHAA GYP

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13094-1-unknown	MALRNV...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13094-171-	SMYIDR...	171		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q13094-171-	SMYIDR...	171		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13094-171-	SMYIDR...	171		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...SSFPQS	373	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000430391
	...AAGYP	533	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)