TopFIND 4.0

Q13202: Dual specificity protein phosphatase 8

General Information

Protein names
- Dual specificity protein phosphatase 8
- 3.1.3.16
- 3.1.3.48
- Dual specificity protein phosphatase hVH-5
Gene names DUSP8
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q13202

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGDRLPRKV MDAKKLASLL RGGPGGPLVI DSRSFVEYNS WHVLSSVNIC CSKLVKRRLQ 
        70         80         90        100        110        120 
QGKVTIAELI QPAARSQVEA TEPQDVVVYD QSTRDASVLA ADSFLSILLS KLDGCFDSVA 
       130        140        150        160        170        180 
ILTGGFATFS SCFPGLCEGK PAALLPMSLS QPCLPVPSVG LTRILPHLYL GSQKDVLNKD 
       190        200        210        220        230        240 
LMTQNGISYV LNASNSCPKP DFICESRFMR VPINDNYCEK LLPWLDKSIE FIDKAKLSSC 
       250        260        270        280        290        300 
QVIVHCLAGI SRSATIAIAY IMKTMGMSSD DAYRFVKDRR PSISPNFNFL GQLLEYERSL 
       310        320        330        340        350        360 
KLLAALQGDP GTPSGTPEPP PSPAAGAPLP RLPPPTSESA ATGNAAAREG GLSAGGEPPA 
       370        380        390        400        410        420 
PPTPPATSAL QQGLRGLHLS SDRLQDTNRL KRSFSLDIKS AYAPSRRPDG PGPPDPGEAP 
       430        440        450        460        470        480 
KLCKLDSPSG AALGLSSPSP DSPDAAPEAR PRPRRRPRPP AGSPARSPAH SLGLNFGDAA 
       490        500        510        520        530        540 
RQTPRHGLSA LSAPGLPGPG QPAGPGAWAP PLDSPGTPSP DGPWCFSPEG AQGAGGVLFA 
       550        560        570        580        590        600 
PFGRAGAPGP GGGSDLRRRE AARAEPRDAR TGWPEEPAPE TQFKRRSCQM EFEEGMVEGR 
       610        620    
ARGEELAALG KQASFSGSVE VIEVS

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q13202-1-unknown MAGDRL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q13202-411-unknown PGPPDP... 411 inferred from cleavage unknown TopFIND Inferred from cleavage TC19411

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)