Q13228: Methanethiol oxidase {ECO:0000303|PubMed:29255262}

General Information

Protein names	- Methanethiol oxidase {ECO:0000303\|PubMed:29255262} - MTO {ECO:0000303\|PubMed:29255262} - 1.8.3.4 {ECO:0000269\|PubMed:29255262} - 56 kDa selenium-binding protein - SBP56 - SP56 - Selenium-binding protein 1
Gene names	SELENBP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13228

9 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Selenium-binding protein 1 - Isoform 3 of Selenium-binding protein 1 - Isoform 2 of Methanethiol oxidase - Isoform 3 of Methanethiol oxidase - Isoform 4 of Methanethiol oxidase

Sequence View

        10         20         30         40         50         60
MATKCGNCGP GYSTPLEAMK GPREEIVYLP CIYRNTGTEA PDYLATVDVD PKSPQYCQVI
        70         80         90        100        110        120
HRLPMPNLKD ELHHSGWNTC SSCFGDSTKS RTKLVLPSLI SSRIYVVDVG SEPRAPKLHK
       130        140        150        160        170        180
VIEPKDIHAK CELAFLHTSH CLASGEVMIS SLGDVKGNGK GGFVLLDGET FEVKGTWERP
       190        200        210        220        230        240
GGAAPLGYDF WYQPRHNVMI STEWAAPNVL RDGFNPADVE AGLYGSHLYV WDWQRHEIVQ
       250        260        270        280        290        300
TLSLKDGLIP LEIRFLHNPD AAQGFVGCAL SSTIQRFYKN EGGTWSVEKV IQVPPKKVKG
       310        320        330        340        350        360
WLLPEMPGLI TDILLSLDDR FLYFSNWLHG DLRQYDISDP QRPRLTGQLF LGGSIVKGGP
       370        380        390        400        410        420
VQVLEDEELK SQPEPLVVKG KRVAGGPQMI QLSLDGKRLY ITTSLYSAWD KQFYPDLIRE
       430        440        450        460        470
GSVMLQVDVD TVKGGLKLNP NFLVDFGKEP LGPALAHELR YPGGDCSSDI WI         10         20         30         40         50         60
MATKCGNCGP GYSTPLEAMK GPREEIVYLP CIYRNTGTEA PDYLATVDVD PKSPQYCQVI
        70         80         90        100        110        120
HRLPMPNLKD ELHHSGWNTC SSCFGDSTKS RTKLVLPSLI SSRIYVVDVG SEPRAPKLHK
       130        140        150        160        170        180
VIEPKDIHAK CELAFLHTSH CLASGEVMIS SLGDVKGNGK GGFVLLDGET FEVKGTWERP
       190        200        210        220        230        240
GGAAPLGYDF WYQPRHNVMI STEWAAPNVL RDGFNPADVE AGLYGSHLYV WDWQRHEIVQ
       250        260        270        280        290        300
TLSLKDGLIP LEIRFLHNPD AAQGFVGCAL SSTIQRFYKN EGGTWSVEKV IQVPPKKVKG
       310        320        330        340        350        360
WLLPEMPGLI TDILLSLDDR FLYFSNWLHG DLRQYDISDP QRPRLTGQLF LGGSIVKGGP
       370        380        390        400        410        420
VQVLEDEELK SQPEPLVVKG KRVAGGPQMI QLSLDGKRLY ITTSLYSAWD KQFYPDLIRE
       430        440        450        460        470
GSVMLQVDVD TVKGGLKLNP NFLVDFGKEP LGPALAHELR YPGGDCSSDI WI         10         20         30         40         50         60
MATKCGNCGP GYSTPLEAMK GPREEIVYLP CIYRNTGTEA PDYLATVDVD PKSPQYCQVI
        70         80         90        100        110        120
HRLPMPNLKD ELHHSGWNTC SSCFGDSTKS RTKLVLPSLI SSRIYVVDVG SEPRAPKLHK
       130        140        150        160        170        180
VIEPKDIHAK CELAFLHTSH CLASGEVMIS SLGDVKGNGK GGFVLLDGET FEVKGTWERP
       190        200        210        220        230        240
GGAAPLGYDF WYQPRHNVMI STEWAAPNVL RDGFNPADVE AGLYGSHLYV WDWQRHEIVQ
       250        260        270        280        290        300
TLSLKDGLIP LEIRFLHNPD AAQGFVGCAL SSTIQRFYKN EGGTWSVEKV IQVPPKKVKG
       310        320        330        340        350        360
WLLPEMPGLI TDILLSLDDR FLYFSNWLHG DLRQYDISDP QRPRLTGQLF LGGSIVKGGP
       370        380        390        400        410        420
VQVLEDEELK SQPEPLVVKG KRVAGGPQMI QLSLDGKRLY ITTSLYSAWD KQFYPDLIRE
       430        440        450        460        470
GSVMLQVDVD TVKGGLKLNP NFLVDFGKEP LGPALAHELR YPGGDCSSDI WI         10         20         30         40         50         60
MATKCGNCGP GYSTPLEAMK GPREEIVYLP CIYRNTGTEA PDYLATVDVD PKSPQYCQVI
        70         80         90        100        110        120
HRLPMPNLKD ELHHSGWNTC SSCFGDSTKS RTKLVLPSLI SSRIYVVDVG SEPRAPKLHK
       130        140        150        160        170        180
VIEPKDIHAK CELAFLHTSH CLASGEVMIS SLGDVKGNGK GGFVLLDGET FEVKGTWERP
       190        200        210        220        230        240
GGAAPLGYDF WYQPRHNVMI STEWAAPNVL RDGFNPADVE AGLYGSHLYV WDWQRHEIVQ
       250        260        270        280        290        300
TLSLKDGLIP LEIRFLHNPD AAQGFVGCAL SSTIQRFYKN EGGTWSVEKV IQVPPKKVKG
       310        320        330        340        350        360
WLLPEMPGLI TDILLSLDDR FLYFSNWLHG DLRQYDISDP QRPRLTGQLF LGGSIVKGGP
       370        380        390        400        410        420
VQVLEDEELK SQPEPLVVKG KRVAGGPQMI QLSLDGKRLY ITTSLYSAWD KQFYPDLIRE
       430        440        450        460        470
GSVMLQVDVD TVKGGLKLNP NFLVDFGKEP LGPALAHELR YPGGDCSSDI WI         10         20         30         40         50         60
MATKCGNCGP GYSTPLEAMK GPREEIVYLP CIYRNTGTEA PDYLATVDVD PKSPQYCQVI
        70         80         90        100        110        120
HRLPMPNLKD ELHHSGWNTC SSCFGDSTKS RTKLVLPSLI SSRIYVVDVG SEPRAPKLHK
       130        140        150        160        170        180
VIEPKDIHAK CELAFLHTSH CLASGEVMIS SLGDVKGNGK GGFVLLDGET FEVKGTWERP
       190        200        210        220        230        240
GGAAPLGYDF WYQPRHNVMI STEWAAPNVL RDGFNPADVE AGLYGSHLYV WDWQRHEIVQ
       250        260        270        280        290        300
TLSLKDGLIP LEIRFLHNPD AAQGFVGCAL SSTIQRFYKN EGGTWSVEKV IQVPPKKVKG
       310        320        330        340        350        360
WLLPEMPGLI TDILLSLDDR FLYFSNWLHG DLRQYDISDP QRPRLTGQLF LGGSIVKGGP
       370        380        390        400        410        420
VQVLEDEELK SQPEPLVVKG KRVAGGPQMI QLSLDGKRLY ITTSLYSAWD KQFYPDLIRE
       430        440        450        460        470
GSVMLQVDVD TVKGGLKLNP NFLVDFGKEP LGPALAHELR YPGGDCSSDI WI

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13228-2-unknown	MATKCG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13228-1-unknown	MATKCG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88908
Q13228-2-Acetylation	ATKCGN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13228-2-Acetylation	ATKCGN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q13228-2-Acetylation	ATKCGN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q13228-2-Acetylation	ATKCGN...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q13228-2-Acetylation	ATKCGN...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110369
Q13228-65-unknown	MPNLKD...	65		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88907
Q13228-92-	TKLVLP...	92			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q13228-92-unknown	TKLVLP...	92		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183050
Q13228-104-acetylation	IYVVDV...	104	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q13228-104-acetylation	IYVVDV...	104	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183042
Q13228-196-acetylation	HNVMIS...	196	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q13228-196-acetylation	HNVMIS...	196	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183045
Q13228-196-acetylation	HNVMIS...	196	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183044
Q13228-255-acetylation	FLHNPD...	255	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q13228-255-acetylation	FLHNPD...	255	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183048
Q13228-255-acetylation	FLHNPD...	255	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183047

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SDIWI	472	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SDIWI	472	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84525
...SDIWI	472	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84526

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)