Q13319: Cyclin-dependent kinase 5 activator 2
| Protein names | - Cyclin-dependent kinase 5 activator 2 - CDK5 activator 2 - Cyclin-dependent kinase 5 regulatory subunit 2 - p39 - p39I |
|---|---|
| Gene names | CDK5R2 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q13319 |
5
N-termini
4
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGTVLSLSPA SSAKGRRPGG LPEEKKKAPP AGDEALGGYG APPVGKGGKG ESRLKRPSVL
70 80 90 100 110 120
ISALTWKRLV AASAKKKKGS KKVTPKPAST GPDPLVQQRN RENLLRKGRD PPDGGGTAKP
130 140 150 160 170 180
LAVPVPTVPA AAATCEPPSG GSAAAQPPGS GGGKPPPPPP PAPQVAPPVP GGSPRRVIVQ
190 200 210 220 230 240
ASTGELLRCL GDFVCRRCYR LKELSPGELV GWFRGVDRSL LLQGWQDQAF ITPANLVFVY
250 260 270 280 290 300
LLCRESLRGD ELASAAELQA AFLTCLYLAY SYMGNEISYP LKPFLVEPDK ERFWQRCLRL
310 320 330 340 350 360
IQRLSPQMLR LNADPHFFTQ VFQDLKNEGE AAASGGGPPS GGAPAASSAA RDSCAAGTKH
WTMNLDR
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
5 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q13319-0-unknown | RMGTVL... | 0 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q13319-2-unknown | MGTVLS... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q13319-101-unknown | RENLLR... | 101 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1062 | |||
| Q13319-106-unknown | RKGRDP... | 106 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1063 | |||
| Q13319-109-unknown | RDPPDG... | 109 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1064 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...VQQRNR | 100 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1062 | |||
| ...RENLLR | 105 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1063 | |||
| ...LLRKGR | 108 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1064 | |||
| ...MNLDR | 367 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CAN2_HUMAN | 100 | QRNR.|.RENL | inferred from experiment | unknown | MEROPS | Tsai LH | Patzke H et al.:Calpain-mediated cleavage of th... (C02.002) | 11784720, |
| CAN2_HUMAN | 105 | NLLR.|.RKGR | inferred from experiment | unknown | MEROPS | Tsai LH | Patzke H et al.:Calpain-mediated cleavage of th... (C02.002) | 11784720, |
| CAN2_HUMAN | 108 | RKGR.|.RDPP | inferred from experiment | unknown | MEROPS | Tsai LH | Patzke H et al.:Calpain-mediated cleavage of th... (C02.002) | 11784720, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|