Q15005: Signal peptidase complex subunit 2

General Information

Protein names	- Signal peptidase complex subunit 2 - 3.4.-.- - Microsomal signal peptidase 25 kDa subunit - SPase 25 kDa subunit
Gene names	SPCS2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15005

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAAVQGGR SGGSGGCSGA GGASNCGTGS GRSGLLDKWK IDDKPVKIDK WDGSAVKNSL
        70         80         90        100        110        120
DDSAKKVLLE KYKYVENFGL IDGRLTICTI SCFFAIVALI WDYMHPFPES KPVLALCVIS
       130        140        150        160        170        180
YFVMMGILTI YTSYKEKSIF LVAHRKDPTG MDPDDIWQLS SSLKRFDDKY TLKLTFISGR
       190        200        210        220
TKQQREAEFT KSIAKFFDHS GTLVMDAYEP EISRLHDSLA IERKIK

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q15005-2-unknown	MAAAAV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15005-2-Acetylation	AAAAVQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15005-2-Acetylation	AAAAVQ...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q15005-2-	AAAAVQ...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...QLSSSL	162	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000434706
	...ERKIK	226	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)