Q15054: DNA polymerase delta subunit 3

General Information

Protein names	- DNA polymerase delta subunit 3 - DNA polymerase delta subunit C {ECO:0000303\|PubMed:11595739} - DNA polymerase delta subunit p66 - DNA polymerase delta subunit p68 {ECO:0000303\|PubMed:22148433, ECO:0000303\|PubMed:22801543}
Gene names	POLD3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15054

8 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of DNA polymerase delta subunit 3 - Isoform 3 of DNA polymerase delta subunit 3

Sequence View

        10         20         30         40         50         60
MADQLYLENI DEFVTDQNKI VTYKWLSYTL GVHVNQAKQM LYDYVERKRK ENSGAQLHVT
        70         80         90        100        110        120
YLVSGSLIQN GHSCHKVAVV REDKLEAVKS KLAVTASIHV YSIQKAMLKD SGPLFNTDYD
       130        140        150        160        170        180
ILKSNLQNCS KFSAIQCAAA VPRAPAESSS SSKKFEQSHL HMSSETQANN ELTTNGHGPP
       190        200        210        220        230        240
ASKQVSQQPK GIMGMFASKA AAKTQETNKE TKTEAKEVTN ASAAGNKAPG KGNMMSNFFG
       250        260        270        280        290        300
KAAMNKFKVN LDSEQAVKEE KIVEQPTVSV TEPKLATPAG LKKSSKKAEP VKVLQKEKKR
       310        320        330        340        350        360
GKRVALSDDE TKETENMRKK RRRIKLPESD SSEDEVFPDS PGAYEAESPS PPPPPSPPLE
       370        380        390        400        410        420
PVPKTEPEPP SVKSSSGENK RKRKRVLKSK TYLDGEGCIV TEKVYESESC TDSEEELNMK
       430        440        450        460
TSSVHRPPAM TVKKEPREER KGPKKGTAAL GKANRQVSIT GFFQRK         10         20         30         40         50         60
MADQLYLENI DEFVTDQNKI VTYKWLSYTL GVHVNQAKQM LYDYVERKRK ENSGAQLHVT
        70         80         90        100        110        120
YLVSGSLIQN GHSCHKVAVV REDKLEAVKS KLAVTASIHV YSIQKAMLKD SGPLFNTDYD
       130        140        150        160        170        180
ILKSNLQNCS KFSAIQCAAA VPRAPAESSS SSKKFEQSHL HMSSETQANN ELTTNGHGPP
       190        200        210        220        230        240
ASKQVSQQPK GIMGMFASKA AAKTQETNKE TKTEAKEVTN ASAAGNKAPG KGNMMSNFFG
       250        260        270        280        290        300
KAAMNKFKVN LDSEQAVKEE KIVEQPTVSV TEPKLATPAG LKKSSKKAEP VKVLQKEKKR
       310        320        330        340        350        360
GKRVALSDDE TKETENMRKK RRRIKLPESD SSEDEVFPDS PGAYEAESPS PPPPPSPPLE
       370        380        390        400        410        420
PVPKTEPEPP SVKSSSGENK RKRKRVLKSK TYLDGEGCIV TEKVYESESC TDSEEELNMK
       430        440        450        460
TSSVHRPPAM TVKKEPREER KGPKKGTAAL GKANRQVSIT GFFQRK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q15054-2-unknown	MADQLY...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15054-2-Acetylation	ADQLYL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15054-2-Acetylation	ADQLYL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q15054-40-unknown	MLYDYV...	40		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73195
Q15054-40-unknown	MLYDYV...	40		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000431239
Q15054-40-unknown	MLYDYV...	40		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000432951
Q15054-40-unknown	MLYDYV...	40		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000432233
Q15054-40-unknown	MLYDYV...	40		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000437231
Q15054-107-unknown	MLKDSG...	107		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73196
Q15054-107-unknown	MLKDSG...	107		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000436018
Q15054-107-unknown	MLKDSG...	107		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108952
Q15054-342-	GAYEAE...	342			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q15054-342-unknown	GAYEAE...	342		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171151
Q15054-342-unknown	GAYEAE...	342		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171152
Q15054-343-	AYEAES...	343			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q15054-343-unknown	AYEAES...	343		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172426
Q15054-343-unknown	AYEAES...	343		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172427

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AESSSS	150	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431239
...AESSSS	150	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107499
...AESSSS	150	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107498
...TTNGHG	177	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437231
...TTNGHG	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107505
...TTNGHG	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107504
...TQETNK	208	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000432233
...TQETNK	208	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107502
...TQETNK	208	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107501
...FFQRK	466	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FFQRK	466	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68814
...FFQRK	466	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68813

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)