Q15078: Cyclin-dependent kinase 5 activator 1
| Protein names | - Cyclin-dependent kinase 5 activator 1 - CDK5 activator 1 - Cyclin-dependent kinase 5 regulatory subunit 1 - TPKII regulatory subunit - Cyclin-dependent kinase 5 activator 1, p35 - p35 - Cyclin-dependent kinase 5 activator 1, p25 - p25 - Tau protein kinase II 23 kDa subunit - p23 |
|---|---|
| Gene names | CDK5R1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q15078 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGTVLSLSPS YRKATLFEDG AATVGHYTAV QNSKNAKDKN LKRHSIISVL PWKRIVAVSA
70 80 90 100 110 120
KKKNSKKVQP NSSYQNNITH LNNENLKKSL SCANLSTFAQ PPPAQPPAPP ASQLSGSQTG
130 140 150 160 170 180
GSSSVKKAPH PAVTSAGTPK RVIVQASTSE LLRCLGEFLC RRCYRLKHLS PTDPVLWLRS
190 200 210 220 230 240
VDRSLLLQGW QDQGFITPAN VVFLYMLCRD VISSEVGSDH ELQAVLLTCL YLSYSYMGNE
250 260 270 280 290 300
ISYPLKPFLV ESCKEAFWDR CLSVINLMSS KMLQINADPH YFTQVFSDLK NESGQEDKKR
LLLGLDR
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q15078-2-unknown | GTVLSL... | 2 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q15078-99-unknown | AQPPPA... | 99 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q15078-99-unknown | AQPPPA... | 99 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC833 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...NLSTFA | 98 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC833 | |||
| ...LGLDR | 307 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CAN1_HUMAN | 98 | STFA.|.AQPP | inferred from experiment | unknown | MEROPS | Tsai LH | Lee MS et al.:Neurotoxicity induces cleavage ... (C02.001) | 10830966, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|