Q16401: 26S proteasome non-ATPase regulatory subunit 5

General Information

Protein names	- 26S proteasome non-ATPase regulatory subunit 5 - 26S protease subunit S5 basic - 26S proteasome subunit S5B
Gene names	PSMD5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16401

4 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAQALALLR EVARLEAPLE ELRALHSVLQ AVPLNELRQQ AAELRLGPLF SLLNENHREK
        70         80         90        100        110        120
TTLCVSILER LLQAMEPVHV ARNLRVDLQR GLIHPDDSVK ILTLSQIGRI VENSDAVTEI
       130        140        150        160        170        180
LNNAELLKQI VYCIGGENLS VAKAAIKSLS RISLTQAGLE ALFESNLLDD LKSVMKTNDI
       190        200        210        220        230        240
VRYRVYELII EISSVSPESL NYCTTSGLVT QLLRELTGED VLVRATCIEM VTSLAYTHHG
       250        260        270        280        290        300
RQYLAQEGVI DQISNIIVGA DSDPFSSFYL PGFVKFFGNL AVMDSPQQIC ERYPIFVEKV
       310        320        330        340        350        360
FEMIESQDPT MIGVAVDTVG ILGSNVEGKQ VLQKTGTRFE RLLMRIGHQS KNAPVELKIR
       370        380        390        400        410        420
CLDAISSLLY LPPEQQTDDL LRMTESWFSS LSRDPLELFR GISSQPFPEL HCAALKVFTA
       430        440        450        460        470        480
IANQPWAQKL MFNSPGFVEY VVDRSVEHDK ASKDAKYELV KALANSKTIA EIFGNPNYLR
       490        500
LRTYLSEGPY YVKPVSTTAV EGAE

Isoforms

- Isoform 2 of 26S proteasome non-ATPase regulatory subunit 5

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q16401-1-unknown	MAAQAL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86398
Q16401-2-unknown	MAAQAL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16401-2-Acetylation	AAQALA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16401-2-Acetylation	AAQALA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q16401-2-Acetylation	AAQALA...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q16401-2-Acetylation	AAQALA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q16401-2-Acetylation	AAQALA...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q16401-2-Acetylation	AAQALA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111344
Q16401-75-acetylation	MEPVHV...	75	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q16401-75-acetylation	MEPVHV...	75	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt183074

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...VEGAE	504		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...VEGAE	504	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...VEGAE	504	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt82016
...VEGAE	504		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)