Q16798: NADP-dependent malic enzyme, mitochondrial

General Information

Protein names	- NADP-dependent malic enzyme, mitochondrial - NADP-ME - 1.1.1.40 - Malic enzyme 3
Gene names	ME3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16798

3 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGAALGTGTR LAPWPGRACG ALPRWTPTAP AQGCHSKPGP ARPVPLKKRG YDVTRNPHLN
        70         80         90        100        110        120
KGMAFTLEER LQLGIHGLIP PCFLSQDVQL LRIMRYYERQ QSDLDKYIIL MTLQDRNEKL
       130        140        150        160        170        180
FYRVLTSDVE KFMPIVYTPT VGLACQHYGL TFRRPRGLFI TIHDKGHLAT MLNSWPEDNI
       190        200        210        220        230        240
KAVVVTDGER ILGLGDLGCY GMGIPVGKLA LYTACGGVNP QQCLPVLLDV GTNNEELLRD
       250        260        270        280        290        300
PLYIGLKHQR VHGKAYDDLL DEFMQAVTDK FGINCLIQFE DFANANAFRL LNKYRNKYCM
       310        320        330        340        350        360
FNDDIQGTAS VAVAGILAAL RITKNKLSNH VFVFQGAGEA AMGIAHLLVM ALEKEGVPKA
       370        380        390        400        410        420
EATRKIWMVD SKGLIVKGRS HLNHEKEMFA QDHPEVNSLE EVVRLVKPTA IIGVAAIAGA
       430        440        450        460        470        480
FTEQILRDMA SFHERPIIFA LSNPTSKAEC TAEKCYRVTE GRGIFASGSP FKSVTLEDGK
       490        500        510        520        530        540
TFIPGQGNNA YVFPGVALGV IAGGIRHIPD EIFLLTAEQI AQEVSEQHLS QGRLYPPLST
       550        560        570        580        590        600
IRDVSLRIAI KVLDYAYKHN LASYYPEPKD KEAFVRSLVY TPDYDSFTLD SYTWPKEAMN

VQTV

Isoforms

- Isoform 2 of NADP-dependent malic enzyme, mitochondrial

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q16798-0-unknown	VMGAAL...	0	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q16798-50-	GYDVTR...	50		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q16798-63-unknown	MAFTLE...	63	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000315255

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PHLNKG	61	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437204
...PHLNKG	61	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434431
...HYGLTF	151	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434690
...RSLVYT	580	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431182
...NVQTV	604	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)