Q3THS6: S-adenosylmethionine synthase isoform type-2
| Protein names | - S-adenosylmethionine synthase isoform type-2 - AdoMet synthase 2 - 2.5.1.6 {ECO:0000250|UniProtKB:P31153} - Methionine adenosyltransferase 2 - MAT 2 |
|---|---|
| Gene names | Mat2a |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q3THS6 |
4
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MNGQLNGFHE AFIEEGTFLF TSESVGEGHP DKICDQISDA VLDAHLQQDP DAKVACETVA
70 80 90 100 110 120
KTGMILLAGE ITSRAAIDYQ KVVREAIKHI GYDDSSKGFD YKTCNVLVAL EQQSPDIAQG
130 140 150 160 170 180
VHLDRNEEDI GAGDQGLMFG YATDETEECM PLTIVLAHKL NAKLAELRRN GTLPWLRPDS
190 200 210 220 230 240
KTQVTVQYMQ DRGAVLPIRV HTIVISVQHD EEVCLDEMRD ALKEKVIKAV VPAKYLDEDT
250 260 270 280 290 300
IYHLQPSGRF VIGGPQGDAG LTGRKIIVDT YGGWGAHGGG AFSGKDYTKV DRSAAYAARW
310 320 330 340 350 360
VAKSLVKGGL CRRVLVQVSY AIGVSHPLSI SIFHYGTSQK SERELLEIVK KNFDLRPGVI
370 380 390
VRDLDLKKPI YQRTAAYGHF GRDSFPWEVP KKLKY
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q3THS6-1-unknown | MNGQLN... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q3THS6-10-unknown | EAFIEE... | 10 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| Q3THS6-67-unknown | LAGEIT... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30421 | |||
| Q3THS6-235-unknown | YLDEDT... | 235 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33905 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...TGMILL | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30421 | |||
| ...VVPAKY | 234 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33905 | |||
| ...KKLKY | 395 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CATE_MOUSE | 66 | MILL.|.LAGE | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> METK2_MOUSE @66 | ||
| MMP2_MOUSE | 234 | PAKY.|.YLDE | inferred from experiment | unknown | MEROPS | Overall CM | auf dem Keller U et al.:A statistics-based platform for... (M10.003) | 20305283, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|