Q3TLH4: Protein PRRC2C
| Protein names | - Protein PRRC2C - BAT2 domain-containing protein 1 - HLA-B-associated transcript 2-like 2 - Proline-rich and coiled-coil-containing protein 2C |
|---|---|
| Gene names | Prrc2c |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q3TLH4 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSEKSGQSTK AKDGKKYATL SLFNTYKGKS LETQKTTVAA RHGLQSLGKV GISRRMPPPA
70 80 90 100 110 120
NLPSLKAENK GNDPNVNIVP KDGTGWASKQ EQHEEEKAPE VSPAQPKPGV AAPPEVAPAP
130 140 150 160 170 180
KSWASNKQGG QGDGIQVNSQ FQQEFPSLQA AGDQEKKEKE ANDENYGPGP SLRPPNVACW
190 200 210 220 230 240
RDGGKSAGSP SSDQDEKQLG QDESTAITSE QNDILKVVEK RIACGPPQAK LNGQQPALAS
250 260 270 280 290 300
QYRAMMPPYM FQQYPRMAYP PLHGPMRFPP SLSEANKSLR GRGPPPSWAS EPERPSILSA
310 320 330 340 350 360
SELKELDKFD NLDAEADEGW AGAQMEVDYT EQLNFSDDDE QGSTSPKESS SEDQTAKTPE
370 380 390 400 410 420
STENRKEVDE ASSTKSSSQI PAQPPVTKSP YGKGPPFNQE RGPSSHLPPP PKLLAQQHPP
430 440 450 460 470 480
PPDRQIPGRQ GPFPSKPPVP DNDEIWKQRR KQQSEISAAV ERARKRREEE ERRMEEQRKA
490 500 510 520 530 540
ACAEKLKQLD EKLGIIEKQP SPEELRERER EKERERELEK EKERELEKEQ EKQREMERAR
550 560 570 580 590 600
QQEKELEQQR EKEQELQRLR EQEKEGEPKE QEKEEKVEPQ EPVVEPATEN QESENNCKKE
610 620 630 640 650 660
EEPIFTRQDS NRSEKETTQV VQEAEPESGA QPRPGYFKQF QKSLPPRFQR QQEQMKQQQW
670 680 690 700 710 720
QQQQQQQQQG VLPQTVPSQP SNGSVPPPPH RPLYQPMQPH PQHLASMGFD PRWLMMQSYM
730 740 750 760 770 780
DPRMISGRPA MDIPPIHPGM IPPKPLIRRD QMEGSPNSSE SFEHIARSAR DHGISLSEPR
790 800 810 820 830 840
MMWGSDPYHA EPQQAATPKS AEETGDARPE TAMDHEHMTA AYPVEHSQLE THSKTDVARD
850 860 870 880 890 900
STETEEQKFL SRSLEDVKPR HVDTNTQSAC FDVIDQKSLP TSAEERISAL ESQPARKRSV
910 920 930 940 950 960
SHGSNHAQNA EEQRNEPSVS IPKVINRCMD SKETVEKPEE KPRKDGFLRS SEGPKPEKVY
970 980 990 1000 1010 1020
KSKSETRWGP RPSSNRREEG NDRPVRRSGP IKKPVLRDMK EEREQRKEKE GEKLEKVTEK
1030 1040 1050 1060 1070 1080
VVKAEKPEKK DLPLPLPPPA PAQPQPQPLV SPPVQPEPEK PPSTETSTLT QKPSQDEKPL
1090 1100 1110 1120 1130 1140
EPVGSVQVEP VVKTVNQQSV AAPTVKEEKP PEKVINKDVG IERSRPDSRL AVKKDSSLPT
1150 1160 1170 1180 1190 1200
RTYWKEARDR DWFPDQGYRG RGRGEYYSRG RSYRGSYGGR GRGGRGHTRE YPQYRDNKPR
1210 1220 1230 1240 1250 1260
TEHVPSGPLR QREESETRSE SSDFEVVPKR RRQRGSETDT DSEVHESASD KDSVSKGKLP
1270 1280 1290 1300 1310 1320
KREERPENKK PVKPQSSFKP ENHVRIDNRP LEKPYIREED KSKPGFLPKG EPTRRGRGGT
1330 1340 1350 1360 1370 1380
FRRGGRDPGG RPSRPATLRR PAYRDNQWNT RQAEPPKPED GEPPRRHEQF MPIPADKRPP
1390 1400 1410 1420 1430 1440
KFERKFDPAR ERPRRQRPTR PPRQDKPPRF RRLREREAAS KTSEVLVPSN GTANNVVQEP
1450 1460 1470 1480 1490 1500
VNPPADISGN KTPDLSNQNS SDQANEEWET ASESSDFNER RERDEKKNAD KSSQAVVKAG
1510 1520 1530 1540 1550 1560
ESVLPPKREI AKRSFSSQRP GVDRQNRRGN NGPPKSGRNF SGPRNERRNG PPSKGGKRGP
1570 1580 1590 1600 1610 1620
FDDQASGTAG ADPVSGNSAH HQEGVPNGAG QKNSKDAAGK KREDTKPGPK KPKEKVDALS
1630 1640 1650 1660 1670 1680
QFDLNNYASV VIIDDHPEVT VIEDPQSNLN DDGFTEVVSK KQQKRLQDEE RRKKEEQVVQ
1690 1700 1710 1720 1730 1740
VWSKKNIGEK GRSQTSKLPP RFAKKQATGT QQIQAPPSAP VPVSSSAPGL TAPAAAAPAS
1750 1760 1770 1780 1790 1800
TPAPVPILAS ATALVPVSTP APVLTSCPAP VPTSASAPVP ASTSSPVTAS SSSQPSVPAP
1810 1820 1830 1840 1850 1860
TPVLASASTT VSVPILTSAS IPILASALAP ATVSSPTPVV SATAVPSIST PAVPASAPTA
1870 1880 1890 1900 1910 1920
SVPLAPASAA STVPPPASTV QTQTQTQTHK PVQSPLPPSA PSSKQPPPSI RLPSAQTSNG
1930 1940 1950 1960 1970 1980
TDFVAAGKSM PTSQSHGSLT AELWDSKVAA PAVLNDISKK LGPISPPQPP SVSAWNKPLT
1990 2000 2010 2020 2030 2040
SFGSATSSEG TRNGQESGVE IGIDTIQFGA PASNGNENEV VPVLSEKATD KVPEPKEQRQ
2050 2060 2070 2080 2090 2100
KQPRAGPIKA QKLPDLSLVE NKEHKPGPIG KERSLKNRKV KDAQQVEPEG QEKPSPAVVR
2110 2120 2130 2140 2150 2160
STDPETAKET KAVSEMSAEI GAMISVSSAE YGSDAKESVT DYTTPSSSLP NTVATNNAKM
2170 2180 2190 2200 2210 2220
EDTLVNNVPL PNTLPLPKRE TIQQSSSLTS VPPTTFSLTF KMESARKAWE NSPNLREKGS
2230 2240 2250 2260 2270 2280
PVTSTAPPIV SGVSSSASGP STANYSSFSS ASMPQIPVAS VTPTASLSGA GTYTTSSLST
2290 2300 2310 2320 2330 2340
KSTTTSDPPN ICKVKPQQLQ TSSLPSASHF SQLSCMPSLI AQQQQSPQVY VSQSAAAQIP
2350 2360 2370 2380 2390 2400
AFYMDTSHLF NTQHARLAPP SLAQQQGFQP GLSQPTSVQQ IPIPIYAPLQ GQHQAQLSLG
2410 2420 2430 2440 2450 2460
AGPAVSQAQE LFSSSIQPYR SQPAFMQSSL SQPSVVLSGT AIHNFPAVQH QELAKAQSGL
2470 2480 2490 2500 2510 2520
AFQQTSNPQP IPILYDHQLG QASGLGSSQL IDTHLLQARA NLTQASNLYS GQVQQPGQTN
2530 2540 2550 2560 2570 2580
FYNTAQSPSA LQQVTVPLPA SQLSLTNFGS TGQPLIALPQ TLQPQLQHTT PQAQAQSLSR
2590 2600 2610 2620 2630 2640
PAQVSQPFRG LIPAGTQHSM MATTGKMSEM ELKAFGSGID IKPGTPPIGG RSTTPTSSPF
2650 2660 2670 2680 2690 2700
RATSTSPNSQ SSKMNSVVYQ KQFQSAPATV RMAQPFPAQF APQILSQPNL VPPLVRAPHT
2710 2720 2730 2740 2750 2760
NTFPAPVQRP PMALASQMPP PLTTGLMSHA RLPHVARGPC GSLSGVRGNQ AQAALKAEQD
2770 2780 2790 2800 2810 2820
LKAKQRAEVL QSTQRFFSEQ QQNKQIGGKT QRVDSDTSNP ETLSDPPGTC PEKVEEKPPP
2830 2840
APTITTKPVR TGPIKPQAIK TEETKS
Isoforms
- Isoform 5 of Protein PRRC2CSequence View
10 20 30 40 50 60
MSEKSGQSTK AKDGKKYATL SLFNTYKGKS LETQKTTVAA RHGLQSLGKV GISRRMPPPA
70 80 90 100 110 120
NLPSLKAENK GNDPNVNIVP KDGTGWASKQ EQHEEEKAPE VSPAQPKPGV AAPPEVAPAP
130 140 150 160 170 180
KSWASNKQGG QGDGIQVNSQ FQQEFPSLQA AGDQEKKEKE ANDENYGPGP SLRPPNVACW
190 200 210 220 230 240
RDGGKSAGSP SSDQDEKQLG QDESTAITSE QNDILKVVEK RIACGPPQAK LNGQQPALAS
250 260 270 280 290 300
QYRAMMPPYM FQQYPRMAYP PLHGPMRFPP SLSEANKSLR GRGPPPSWAS EPERPSILSA
310 320 330 340 350 360
SELKELDKFD NLDAEADEGW AGAQMEVDYT EQLNFSDDDE QGSTSPKESS SEDQTAKTPE
370 380 390 400 410 420
STENRKEVDE ASSTKSSSQI PAQPPVTKSP YGKGPPFNQE RGPSSHLPPP PKLLAQQHPP
430 440 450 460 470 480
PPDRQIPGRQ GPFPSKPPVP DNDEIWKQRR KQQSEISAAV ERARKRREEE ERRMEEQRKA
490 500 510 520 530 540
ACAEKLKQLD EKLGIIEKQP SPEELRERER EKERERELEK EKERELEKEQ EKQREMERAR
550 560 570 580 590 600
QQEKELEQQR EKEQELQRLR EQEKEGEPKE QEKEEKVEPQ EPVVEPATEN QESENNCKKE
610 620 630 640 650 660
EEPIFTRQDS NRSEKETTQV VQEAEPESGA QPRPGYFKQF QKSLPPRFQR QQEQMKQQQW
670 680 690 700 710 720
QQQQQQQQQG VLPQTVPSQP SNGSVPPPPH RPLYQPMQPH PQHLASMGFD PRWLMMQSYM
730 740 750 760 770 780
DPRMISGRPA MDIPPIHPGM IPPKPLIRRD QMEGSPNSSE SFEHIARSAR DHGISLSEPR
790 800 810 820 830 840
MMWGSDPYHA EPQQAATPKS AEETGDARPE TAMDHEHMTA AYPVEHSQLE THSKTDVARD
850 860 870 880 890 900
STETEEQKFL SRSLEDVKPR HVDTNTQSAC FDVIDQKSLP TSAEERISAL ESQPARKRSV
910 920 930 940 950 960
SHGSNHAQNA EEQRNEPSVS IPKVINRCMD SKETVEKPEE KPRKDGFLRS SEGPKPEKVY
970 980 990 1000 1010 1020
KSKSETRWGP RPSSNRREEG NDRPVRRSGP IKKPVLRDMK EEREQRKEKE GEKLEKVTEK
1030 1040 1050 1060 1070 1080
VVKAEKPEKK DLPLPLPPPA PAQPQPQPLV SPPVQPEPEK PPSTETSTLT QKPSQDEKPL
1090 1100 1110 1120 1130 1140
EPVGSVQVEP VVKTVNQQSV AAPTVKEEKP PEKVINKDVG IERSRPDSRL AVKKDSSLPT
1150 1160 1170 1180 1190 1200
RTYWKEARDR DWFPDQGYRG RGRGEYYSRG RSYRGSYGGR GRGGRGHTRE YPQYRDNKPR
1210 1220 1230 1240 1250 1260
TEHVPSGPLR QREESETRSE SSDFEVVPKR RRQRGSETDT DSEVHESASD KDSVSKGKLP
1270 1280 1290 1300 1310 1320
KREERPENKK PVKPQSSFKP ENHVRIDNRP LEKPYIREED KSKPGFLPKG EPTRRGRGGT
1330 1340 1350 1360 1370 1380
FRRGGRDPGG RPSRPATLRR PAYRDNQWNT RQAEPPKPED GEPPRRHEQF MPIPADKRPP
1390 1400 1410 1420 1430 1440
KFERKFDPAR ERPRRQRPTR PPRQDKPPRF RRLREREAAS KTSEVLVPSN GTANNVVQEP
1450 1460 1470 1480 1490 1500
VNPPADISGN KTPDLSNQNS SDQANEEWET ASESSDFNER RERDEKKNAD KSSQAVVKAG
1510 1520 1530 1540 1550 1560
ESVLPPKREI AKRSFSSQRP GVDRQNRRGN NGPPKSGRNF SGPRNERRNG PPSKGGKRGP
1570 1580 1590 1600 1610 1620
FDDQASGTAG ADPVSGNSAH HQEGVPNGAG QKNSKDAAGK KREDTKPGPK KPKEKVDALS
1630 1640 1650 1660 1670 1680
QFDLNNYASV VIIDDHPEVT VIEDPQSNLN DDGFTEVVSK KQQKRLQDEE RRKKEEQVVQ
1690 1700 1710 1720 1730 1740
VWSKKNIGEK GRSQTSKLPP RFAKKQATGT QQIQAPPSAP VPVSSSAPGL TAPAAAAPAS
1750 1760 1770 1780 1790 1800
TPAPVPILAS ATALVPVSTP APVLTSCPAP VPTSASAPVP ASTSSPVTAS SSSQPSVPAP
1810 1820 1830 1840 1850 1860
TPVLASASTT VSVPILTSAS IPILASALAP ATVSSPTPVV SATAVPSIST PAVPASAPTA
1870 1880 1890 1900 1910 1920
SVPLAPASAA STVPPPASTV QTQTQTQTHK PVQSPLPPSA PSSKQPPPSI RLPSAQTSNG
1930 1940 1950 1960 1970 1980
TDFVAAGKSM PTSQSHGSLT AELWDSKVAA PAVLNDISKK LGPISPPQPP SVSAWNKPLT
1990 2000 2010 2020 2030 2040
SFGSATSSEG TRNGQESGVE IGIDTIQFGA PASNGNENEV VPVLSEKATD KVPEPKEQRQ
2050 2060 2070 2080 2090 2100
KQPRAGPIKA QKLPDLSLVE NKEHKPGPIG KERSLKNRKV KDAQQVEPEG QEKPSPAVVR
2110 2120 2130 2140 2150 2160
STDPETAKET KAVSEMSAEI GAMISVSSAE YGSDAKESVT DYTTPSSSLP NTVATNNAKM
2170 2180 2190 2200 2210 2220
EDTLVNNVPL PNTLPLPKRE TIQQSSSLTS VPPTTFSLTF KMESARKAWE NSPNLREKGS
2230 2240 2250 2260 2270 2280
PVTSTAPPIV SGVSSSASGP STANYSSFSS ASMPQIPVAS VTPTASLSGA GTYTTSSLST
2290 2300 2310 2320 2330 2340
KSTTTSDPPN ICKVKPQQLQ TSSLPSASHF SQLSCMPSLI AQQQQSPQVY VSQSAAAQIP
2350 2360 2370 2380 2390 2400
AFYMDTSHLF NTQHARLAPP SLAQQQGFQP GLSQPTSVQQ IPIPIYAPLQ GQHQAQLSLG
2410 2420 2430 2440 2450 2460
AGPAVSQAQE LFSSSIQPYR SQPAFMQSSL SQPSVVLSGT AIHNFPAVQH QELAKAQSGL
2470 2480 2490 2500 2510 2520
AFQQTSNPQP IPILYDHQLG QASGLGSSQL IDTHLLQARA NLTQASNLYS GQVQQPGQTN
2530 2540 2550 2560 2570 2580
FYNTAQSPSA LQQVTVPLPA SQLSLTNFGS TGQPLIALPQ TLQPQLQHTT PQAQAQSLSR
2590 2600 2610 2620 2630 2640
PAQVSQPFRG LIPAGTQHSM MATTGKMSEM ELKAFGSGID IKPGTPPIGG RSTTPTSSPF
2650 2660 2670 2680 2690 2700
RATSTSPNSQ SSKMNSVVYQ KQFQSAPATV RMAQPFPAQF APQILSQPNL VPPLVRAPHT
2710 2720 2730 2740 2750 2760
NTFPAPVQRP PMALASQMPP PLTTGLMSHA RLPHVARGPC GSLSGVRGNQ AQAALKAEQD
2770 2780 2790 2800 2810 2820
LKAKQRAEVL QSTQRFFSEQ QQNKQIGGKT QRVDSDTSNP ETLSDPPGTC PEKVEEKPPP
2830 2840
APTITTKPVR TGPIKPQAIK TEETKS
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q3TLH4-1-unknown | MSEKSG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q3TLH4-1-unknown | MSEKSG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86106 | |||
| Q3TLH4-413-unknown | LLAQQH... | 413 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33906 | |||
| Q3TLH4-413-unknown | LLAQQH... | 413 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152205 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...PPPPKL | 412 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33906 | |||
| ...PPPPKL | 412 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt135615 | |||
| ...EETKS | 2846 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...EETKS | 2846 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81724 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MMP2_MOUSE | 412 | PPKL.|.LLAQ | inferred from experiment | unknown | MEROPS | Overall CM | Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) | 20305284, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|