Q49AR2: UPF0489 protein C5orf22

General Information

Protein names	- UPF0489 protein C5orf22
Gene names	C5orf22
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q49AR2

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of UPF0489 protein C5orf22 - Isoform 3 of UPF0489 protein C5orf22

Sequence View

        10         20         30         40         50         60
MSDSAGGRAG LRRYPKLPVW VVEDHQEVLP FIYRAIGSKH LPASNVSFLH FDSHPDLLIP
        70         80         90        100        110        120
VNMPADTVFD KETLFGELSI ENWIMPAVYA GHFSHVIWFH PTWAQQIREG RHHFLVGKDT
       130        140        150        160        170        180
STTTIRVTST DHYFLSDGLY VPEDQLENQK PLQLDVIMVK PYKLCNNQEE NDAVSSAKKP
       190        200        210        220        230        240
KLALEDSENT ASTNCDSSSE GLEKDTATQR SDQTCLEPSC SCSSENQECQ TAASTGEILE
       250        260        270        280        290        300
ILKKGKAFVL DIDLDFFSVK NPFKEMFTQE EYKILQELYQ FKKPGTNLTE EDLVDIVDTR
       310        320        330        340        350        360
IHQLEDLEAT FADLCDGDDE ETVQRWASNP GMESLVPLVQ SLKKRMEVPD YEMVHQAGLT
       370        380        390        400        410        420
CDYSELPHHI STEQEIECLI QSVHYLLKNL PNPTLVTIAR SSLDDYCPSD QVDTIQEKVL
       430        440
NMLRALYGNL DLQVYAAESP PS         10         20         30         40         50         60
MSDSAGGRAG LRRYPKLPVW VVEDHQEVLP FIYRAIGSKH LPASNVSFLH FDSHPDLLIP
        70         80         90        100        110        120
VNMPADTVFD KETLFGELSI ENWIMPAVYA GHFSHVIWFH PTWAQQIREG RHHFLVGKDT
       130        140        150        160        170        180
STTTIRVTST DHYFLSDGLY VPEDQLENQK PLQLDVIMVK PYKLCNNQEE NDAVSSAKKP
       190        200        210        220        230        240
KLALEDSENT ASTNCDSSSE GLEKDTATQR SDQTCLEPSC SCSSENQECQ TAASTGEILE
       250        260        270        280        290        300
ILKKGKAFVL DIDLDFFSVK NPFKEMFTQE EYKILQELYQ FKKPGTNLTE EDLVDIVDTR
       310        320        330        340        350        360
IHQLEDLEAT FADLCDGDDE ETVQRWASNP GMESLVPLVQ SLKKRMEVPD YEMVHQAGLT
       370        380        390        400        410        420
CDYSELPHHI STEQEIECLI QSVHYLLKNL PNPTLVTIAR SSLDDYCPSD QVDTIQEKVL
       430        440
NMLRALYGNL DLQVYAAESP PS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q49AR2-1-unknown	MSDSAG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q49AR2-197-	SSSEGL...	197		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q49AR2-197-	SSSEGL...	197		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q49AR2-197-unknown	SSSEGL...	197		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q49AR2-266-unknown	MFTQEE...	266	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt70162

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ESPPS	442	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ESPPS	442	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65781
...ESPPS	442	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65780

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)