TopFIND 4.0

Q5EBM0: UMP-CMP kinase 2, mitochondrial

General Information

Protein names
- UMP-CMP kinase 2, mitochondrial
- 2.7.4.14
- Nucleoside-diphosphate kinase
- 2.7.4.6
Gene names CMPK2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q5EBM0

4

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAFARRLLRG PLSGPLLGRR GVCAGAMAPP RRFVLELPDC TLAHFALGAD APGDADAPDP 
        70         80         90        100        110        120 
RLAALLGPPE RSYSLCVPVT PDAGCGARVR AARLHQRLLH QLRRGPFQRC QLLRLLCYCP 
       130        140        150        160        170        180 
GGQAGGAQQG FLLRDPLDDP DTRQALLELL GACQEAPRPH LGEFEADPRG QLWQRLWEVQ 
       190        200        210        220        230        240 
DGRRLQVGCA QVVPVPEPPL HPVVPDLPSS VVFPDREAAR AVLEECTSFI PEARAVLDLV 
       250        260        270        280        290        300 
DQCPKQIQKG KFQVVAIEGL DATGKTTVTQ SVADSLKAVL LKSPPSCIGQ WRKIFDDEPT 
       310        320        330        340        350        360 
IIRRAFYSLG NYIVASEIAK ESAKSPVIVD RYWHSTATYA IATEVSGGLQ HLPPAHHPVY 
       370        380        390        400        410        420 
QWPEDLLKPD LILLLTVSPE ERLQRLQGRG MEKTREEAEL EANSVFRQKV EMSYQRMENP 
       430        440    
GCHVVDASPS REKVLQTVLS LIQNSFSEP

Isoforms

- Isoform 2 of UMP-CMP kinase 2, mitochondrial - Isoform 3 of UMP-CMP kinase 2, mitochondrial - Isoform 4 of UMP-CMP kinase 2, mitochondrial

Sequence View

        10         20         30         40         50         60 
MAFARRLLRG PLSGPLLGRR GVCAGAMAPP RRFVLELPDC TLAHFALGAD APGDADAPDP 
        70         80         90        100        110        120 
RLAALLGPPE RSYSLCVPVT PDAGCGARVR AARLHQRLLH QLRRGPFQRC QLLRLLCYCP 
       130        140        150        160        170        180 
GGQAGGAQQG FLLRDPLDDP DTRQALLELL GACQEAPRPH LGEFEADPRG QLWQRLWEVQ 
       190        200        210        220        230        240 
DGRRLQVGCA QVVPVPEPPL HPVVPDLPSS VVFPDREAAR AVLEECTSFI PEARAVLDLV 
       250        260        270        280        290        300 
DQCPKQIQKG KFQVVAIEGL DATGKTTVTQ SVADSLKAVL LKSPPSCIGQ WRKIFDDEPT 
       310        320        330        340        350        360 
IIRRAFYSLG NYIVASEIAK ESAKSPVIVD RYWHSTATYA IATEVSGGLQ HLPPAHHPVY 
       370        380        390        400        410        420 
QWPEDLLKPD LILLLTVSPE ERLQRLQGRG MEKTREEAEL EANSVFRQKV EMSYQRMENP 
       430        440    
GCHVVDASPS REKVLQTVLS LIQNSFSEP         10         20         30         40         50         60 
MAFARRLLRG PLSGPLLGRR GVCAGAMAPP RRFVLELPDC TLAHFALGAD APGDADAPDP 
        70         80         90        100        110        120 
RLAALLGPPE RSYSLCVPVT PDAGCGARVR AARLHQRLLH QLRRGPFQRC QLLRLLCYCP 
       130        140        150        160        170        180 
GGQAGGAQQG FLLRDPLDDP DTRQALLELL GACQEAPRPH LGEFEADPRG QLWQRLWEVQ 
       190        200        210        220        230        240 
DGRRLQVGCA QVVPVPEPPL HPVVPDLPSS VVFPDREAAR AVLEECTSFI PEARAVLDLV 
       250        260        270        280        290        300 
DQCPKQIQKG KFQVVAIEGL DATGKTTVTQ SVADSLKAVL LKSPPSCIGQ WRKIFDDEPT 
       310        320        330        340        350        360 
IIRRAFYSLG NYIVASEIAK ESAKSPVIVD RYWHSTATYA IATEVSGGLQ HLPPAHHPVY 
       370        380        390        400        410        420 
QWPEDLLKPD LILLLTVSPE ERLQRLQGRG MEKTREEAEL EANSVFRQKV EMSYQRMENP 
       430        440    
GCHVVDASPS REKVLQTVLS LIQNSFSEP         10         20         30         40         50         60 
MAFARRLLRG PLSGPLLGRR GVCAGAMAPP RRFVLELPDC TLAHFALGAD APGDADAPDP 
        70         80         90        100        110        120 
RLAALLGPPE RSYSLCVPVT PDAGCGARVR AARLHQRLLH QLRRGPFQRC QLLRLLCYCP 
       130        140        150        160        170        180 
GGQAGGAQQG FLLRDPLDDP DTRQALLELL GACQEAPRPH LGEFEADPRG QLWQRLWEVQ 
       190        200        210        220        230        240 
DGRRLQVGCA QVVPVPEPPL HPVVPDLPSS VVFPDREAAR AVLEECTSFI PEARAVLDLV 
       250        260        270        280        290        300 
DQCPKQIQKG KFQVVAIEGL DATGKTTVTQ SVADSLKAVL LKSPPSCIGQ WRKIFDDEPT 
       310        320        330        340        350        360 
IIRRAFYSLG NYIVASEIAK ESAKSPVIVD RYWHSTATYA IATEVSGGLQ HLPPAHHPVY 
       370        380        390        400        410        420 
QWPEDLLKPD LILLLTVSPE ERLQRLQGRG MEKTREEAEL EANSVFRQKV EMSYQRMENP 
       430        440    
GCHVVDASPS REKVLQTVLS LIQNSFSEP



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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VFRQKV 409 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt66679
    ...SFSEP 449 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)