Q5SV42: Leukocyte elastase inhibitor C

General Information

Protein names	- Leukocyte elastase inhibitor C - Serine protease inhibitor EIC - Serpin B1c
Gene names	Serpinb1c
Organism	Mus musculus
Protease Family
Protease ID	I04.006
Chromosome location
UniProt ID	Q5SV42

2 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGQLSSANNL FALELFHTLN ESNPTGNTIF SPVSISSALA MVYLGARGST AAQLSKTLHF
        70         80         90        100        110        120
DSAEDIHSQF QSLTAEVSKR GASHTLKLAN RLYGEKTYNF LPEYLASIQK TYSADLALVD
       130        140        150        160        170        180
FQHASEDARK EINQWVKGQT EEKIQELFAV GVVDSMTKLV LVNATYFKGM WQKKFMARDT
       190        200        210        220        230        240
TDAPFRLSKK VTKTVKMMYL KNNLPFGYIP DLKCKVLEMP YQGGELSMVI LLPEDIEDET
       250        260        270        280        290        300
TGLEEIEKQL TLEKLQECEN LQNIDVCVKL PKFKMEESYI LNSNLGQLGV QDLFSSSKAD
       310        320        330        340        350        360
LSGMSGSRDL FISKIVHKSY VEVNEEGTET DAAMPGTVVG CCLMPMEFTV DHPFLFFIRH
       370
NPTAHVLFLG RVCSP

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q5SV42-1-unknown	MGQLSS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q5SV42-294-unknown	FSSSKA...	294	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29131
Q5SV42-294-unknown	FSSSKA...	294	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30454

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MMYLKN	201	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117305
...GVQDLF	293	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29131
...GVQDLF	293	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30454
...RVCSP	375	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	293	QDLF.\|.FSSS	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ILEUC_MOUSE @293
CATE_MOUSE	293	QDLF.\|.FSSS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ILEUC_MOUSE @293

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)