Q5T5Y3: Calmodulin-regulated spectrin-associated protein 1
| Protein names | - Calmodulin-regulated spectrin-associated protein 1 |
|---|---|
| Gene names | CAMSAP1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q5T5Y3 |
10
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MVDASGRAAA EGWRKMEAPP DGAADLVPLD RYDAARAKIA ANLQWICAKA YGRDNIPEDL
70 80 90 100 110 120
RDPFYVDQYE QEHIKPPVIK LLLSSELYCR VCSLILKGDQ VAALQGHQSV IQALSRKGIY
130 140 150 160 170 180
VMESDDTPVT ESDLSRAPIK MSAHMAMVDA LMMAYTVEMI SIEKVVASVK RFSTFSASKE
190 200 210 220 230 240
LPYDLEDAMV FWINKVNLKM REITEKEVKL KQQLLESPAH QKVRYRREHL SARQSPYFPL
250 260 270 280 290 300
LEDLMRDGSD GAALLAVIHY YCPEQMKLDD ICLKEVTSMA DSLYNIRLLR EFSNEYLNKC
310 320 330 340 350 360
FYLTLEDMLY APLVLKPNVM VFIAELFWWF ENVKPDFVQP RDVQELKDAK TVLHQKSSRP
370 380 390 400 410 420
PVPISNATKR SFLGSPAAGT LAELQPPVQL PAEGCHRHYL HPEEPEYLGK GTAAFSPSHP
430 440 450 460 470 480
LLPLRQKQQK SIQGEDIPDQ RHRSNSLTRV DGQPRGAAIA WPEKKTRPAS QPTPFALHHA
490 500 510 520 530 540
ASCEVDPSSG DSISLARSIS KDSLASNIVN LTPQNQPHPT ATKSHGKSLL SNVSIEDEEE
550 560 570 580 590 600
ELVAIVRADV VPQQADPEFP RASPRALGLT ANARSPQGQL DTSESKPDSF FLEPLMPAVL
610 620 630 640 650 660
KPAKEKQVIT KEDERGEGRP RSIVSRRPSE GPQPLVRRKM TGSRDLNRTF TPIPCSEFPM
670 680 690 700 710 720
GIDPTETGPL SVETAGEVCG GPLALGGFDP FPQGPSTDGF FLHVGRADED TEGRLYVSCS
730 740 750 760 770 780
KSPNSHDSEP WTLLRQDSDS DVVDIEEAEH DFMGEAHPVV FSRYIGEEES AKLQEDMKVK
790 800 810 820 830 840
EHEDKDDASG RSSPCLSTAS QMSSVSMASG SVKMTSFAER KLQRLNSCET KSSTSSSQKT
850 860 870 880 890 900
TPDASESCPA PLTTWRQKRE QSPSQHGKDP ASLLASELVQ LHMQLEEKRR AIEAQKKKME
910 920 930 940 950 960
ALSARQRLKL GKAAFLHVVK KGKAEAAPPL RPEHFAKEYS QHNGEDCGDA VSKTEDFLVK
970 980 990 1000 1010 1020
EEQREELLHE PQDVDKESLA FAQQHKAKDP VALHELERNK VISAALLEDT VGEVVDVNEC
1030 1040 1050 1060 1070 1080
DLSIEKLNET ISTLQQAILK ISQQQEQLLM KSPTVPVPGS KNNSQDHKVK APVHFVEPLS
1090 1100 1110 1120 1130 1140
PTGVAGHRKA PRLGQGRNSR SGRPAELKVP KDRPQGSSRS KTPTPSVETL PHLRPFPASS
1150 1160 1170 1180 1190 1200
HPRTPTDPGL DSALEPSGDP HGKCLFDSYR LHDESNQRTL TLSSSKDANI LSEQMSLKEV
1210 1220 1230 1240 1250 1260
LDASVKEVGS SSSDVSGKES VPVEEPLRSR ASLIEVDLSD LKAPDEDGEL VSLDGSADLV
1270 1280 1290 1300 1310 1320
SEGDQKPGVG FFFKDEQKAE DELAKKRAAF LLKQQRKAEE ARVRKQQLEA EVELKRDEAR
1330 1340 1350 1360 1370 1380
RKAEEDRVRK EEEKARRELI KQEYLRRKQQ QILEEQGLGK PKSKPKKPRP KSVHREESCS
1390 1400 1410 1420 1430 1440
DSGTKCSSTP DNLSRTQSGS SLSLASAATT EPESVHSGGT PSQRVESMEA LPILSRNPSR
1450 1460 1470 1480 1490 1500
STDRDWETAS AASSLASVAE YTGPKLFKEP SSKSNKPIIH NAISHCCLAG KVNEPHKNSI
1510 1520 1530 1540 1550 1560
LEELEKCDAN HYIILFRDAG CQFRALYCYY PDTEEIYKLT GTGPKNITKK MIDKLYKYSS
1570 1580 1590 1600
DRKQFNLIPA KTMSVSVDAL TIHNHLWQPK RPAVPKKAQT RK
Isoforms
- Isoform 2 of Calmodulin-regulated spectrin-associated protein 1 - Isoform 3 of Calmodulin-regulated spectrin-associated protein 1Sequence View
10 20 30 40 50 60
MVDASGRAAA EGWRKMEAPP DGAADLVPLD RYDAARAKIA ANLQWICAKA YGRDNIPEDL
70 80 90 100 110 120
RDPFYVDQYE QEHIKPPVIK LLLSSELYCR VCSLILKGDQ VAALQGHQSV IQALSRKGIY
130 140 150 160 170 180
VMESDDTPVT ESDLSRAPIK MSAHMAMVDA LMMAYTVEMI SIEKVVASVK RFSTFSASKE
190 200 210 220 230 240
LPYDLEDAMV FWINKVNLKM REITEKEVKL KQQLLESPAH QKVRYRREHL SARQSPYFPL
250 260 270 280 290 300
LEDLMRDGSD GAALLAVIHY YCPEQMKLDD ICLKEVTSMA DSLYNIRLLR EFSNEYLNKC
310 320 330 340 350 360
FYLTLEDMLY APLVLKPNVM VFIAELFWWF ENVKPDFVQP RDVQELKDAK TVLHQKSSRP
370 380 390 400 410 420
PVPISNATKR SFLGSPAAGT LAELQPPVQL PAEGCHRHYL HPEEPEYLGK GTAAFSPSHP
430 440 450 460 470 480
LLPLRQKQQK SIQGEDIPDQ RHRSNSLTRV DGQPRGAAIA WPEKKTRPAS QPTPFALHHA
490 500 510 520 530 540
ASCEVDPSSG DSISLARSIS KDSLASNIVN LTPQNQPHPT ATKSHGKSLL SNVSIEDEEE
550 560 570 580 590 600
ELVAIVRADV VPQQADPEFP RASPRALGLT ANARSPQGQL DTSESKPDSF FLEPLMPAVL
610 620 630 640 650 660
KPAKEKQVIT KEDERGEGRP RSIVSRRPSE GPQPLVRRKM TGSRDLNRTF TPIPCSEFPM
670 680 690 700 710 720
GIDPTETGPL SVETAGEVCG GPLALGGFDP FPQGPSTDGF FLHVGRADED TEGRLYVSCS
730 740 750 760 770 780
KSPNSHDSEP WTLLRQDSDS DVVDIEEAEH DFMGEAHPVV FSRYIGEEES AKLQEDMKVK
790 800 810 820 830 840
EHEDKDDASG RSSPCLSTAS QMSSVSMASG SVKMTSFAER KLQRLNSCET KSSTSSSQKT
850 860 870 880 890 900
TPDASESCPA PLTTWRQKRE QSPSQHGKDP ASLLASELVQ LHMQLEEKRR AIEAQKKKME
910 920 930 940 950 960
ALSARQRLKL GKAAFLHVVK KGKAEAAPPL RPEHFAKEYS QHNGEDCGDA VSKTEDFLVK
970 980 990 1000 1010 1020
EEQREELLHE PQDVDKESLA FAQQHKAKDP VALHELERNK VISAALLEDT VGEVVDVNEC
1030 1040 1050 1060 1070 1080
DLSIEKLNET ISTLQQAILK ISQQQEQLLM KSPTVPVPGS KNNSQDHKVK APVHFVEPLS
1090 1100 1110 1120 1130 1140
PTGVAGHRKA PRLGQGRNSR SGRPAELKVP KDRPQGSSRS KTPTPSVETL PHLRPFPASS
1150 1160 1170 1180 1190 1200
HPRTPTDPGL DSALEPSGDP HGKCLFDSYR LHDESNQRTL TLSSSKDANI LSEQMSLKEV
1210 1220 1230 1240 1250 1260
LDASVKEVGS SSSDVSGKES VPVEEPLRSR ASLIEVDLSD LKAPDEDGEL VSLDGSADLV
1270 1280 1290 1300 1310 1320
SEGDQKPGVG FFFKDEQKAE DELAKKRAAF LLKQQRKAEE ARVRKQQLEA EVELKRDEAR
1330 1340 1350 1360 1370 1380
RKAEEDRVRK EEEKARRELI KQEYLRRKQQ QILEEQGLGK PKSKPKKPRP KSVHREESCS
1390 1400 1410 1420 1430 1440
DSGTKCSSTP DNLSRTQSGS SLSLASAATT EPESVHSGGT PSQRVESMEA LPILSRNPSR
1450 1460 1470 1480 1490 1500
STDRDWETAS AASSLASVAE YTGPKLFKEP SSKSNKPIIH NAISHCCLAG KVNEPHKNSI
1510 1520 1530 1540 1550 1560
LEELEKCDAN HYIILFRDAG CQFRALYCYY PDTEEIYKLT GTGPKNITKK MIDKLYKYSS
1570 1580 1590 1600
DRKQFNLIPA KTMSVSVDAL TIHNHLWQPK RPAVPKKAQT RK
10 20 30 40 50 60
MVDASGRAAA EGWRKMEAPP DGAADLVPLD RYDAARAKIA ANLQWICAKA YGRDNIPEDL
70 80 90 100 110 120
RDPFYVDQYE QEHIKPPVIK LLLSSELYCR VCSLILKGDQ VAALQGHQSV IQALSRKGIY
130 140 150 160 170 180
VMESDDTPVT ESDLSRAPIK MSAHMAMVDA LMMAYTVEMI SIEKVVASVK RFSTFSASKE
190 200 210 220 230 240
LPYDLEDAMV FWINKVNLKM REITEKEVKL KQQLLESPAH QKVRYRREHL SARQSPYFPL
250 260 270 280 290 300
LEDLMRDGSD GAALLAVIHY YCPEQMKLDD ICLKEVTSMA DSLYNIRLLR EFSNEYLNKC
310 320 330 340 350 360
FYLTLEDMLY APLVLKPNVM VFIAELFWWF ENVKPDFVQP RDVQELKDAK TVLHQKSSRP
370 380 390 400 410 420
PVPISNATKR SFLGSPAAGT LAELQPPVQL PAEGCHRHYL HPEEPEYLGK GTAAFSPSHP
430 440 450 460 470 480
LLPLRQKQQK SIQGEDIPDQ RHRSNSLTRV DGQPRGAAIA WPEKKTRPAS QPTPFALHHA
490 500 510 520 530 540
ASCEVDPSSG DSISLARSIS KDSLASNIVN LTPQNQPHPT ATKSHGKSLL SNVSIEDEEE
550 560 570 580 590 600
ELVAIVRADV VPQQADPEFP RASPRALGLT ANARSPQGQL DTSESKPDSF FLEPLMPAVL
610 620 630 640 650 660
KPAKEKQVIT KEDERGEGRP RSIVSRRPSE GPQPLVRRKM TGSRDLNRTF TPIPCSEFPM
670 680 690 700 710 720
GIDPTETGPL SVETAGEVCG GPLALGGFDP FPQGPSTDGF FLHVGRADED TEGRLYVSCS
730 740 750 760 770 780
KSPNSHDSEP WTLLRQDSDS DVVDIEEAEH DFMGEAHPVV FSRYIGEEES AKLQEDMKVK
790 800 810 820 830 840
EHEDKDDASG RSSPCLSTAS QMSSVSMASG SVKMTSFAER KLQRLNSCET KSSTSSSQKT
850 860 870 880 890 900
TPDASESCPA PLTTWRQKRE QSPSQHGKDP ASLLASELVQ LHMQLEEKRR AIEAQKKKME
910 920 930 940 950 960
ALSARQRLKL GKAAFLHVVK KGKAEAAPPL RPEHFAKEYS QHNGEDCGDA VSKTEDFLVK
970 980 990 1000 1010 1020
EEQREELLHE PQDVDKESLA FAQQHKAKDP VALHELERNK VISAALLEDT VGEVVDVNEC
1030 1040 1050 1060 1070 1080
DLSIEKLNET ISTLQQAILK ISQQQEQLLM KSPTVPVPGS KNNSQDHKVK APVHFVEPLS
1090 1100 1110 1120 1130 1140
PTGVAGHRKA PRLGQGRNSR SGRPAELKVP KDRPQGSSRS KTPTPSVETL PHLRPFPASS
1150 1160 1170 1180 1190 1200
HPRTPTDPGL DSALEPSGDP HGKCLFDSYR LHDESNQRTL TLSSSKDANI LSEQMSLKEV
1210 1220 1230 1240 1250 1260
LDASVKEVGS SSSDVSGKES VPVEEPLRSR ASLIEVDLSD LKAPDEDGEL VSLDGSADLV
1270 1280 1290 1300 1310 1320
SEGDQKPGVG FFFKDEQKAE DELAKKRAAF LLKQQRKAEE ARVRKQQLEA EVELKRDEAR
1330 1340 1350 1360 1370 1380
RKAEEDRVRK EEEKARRELI KQEYLRRKQQ QILEEQGLGK PKSKPKKPRP KSVHREESCS
1390 1400 1410 1420 1430 1440
DSGTKCSSTP DNLSRTQSGS SLSLASAATT EPESVHSGGT PSQRVESMEA LPILSRNPSR
1450 1460 1470 1480 1490 1500
STDRDWETAS AASSLASVAE YTGPKLFKEP SSKSNKPIIH NAISHCCLAG KVNEPHKNSI
1510 1520 1530 1540 1550 1560
LEELEKCDAN HYIILFRDAG CQFRALYCYY PDTEEIYKLT GTGPKNITKK MIDKLYKYSS
1570 1580 1590 1600
DRKQFNLIPA KTMSVSVDAL TIHNHLWQPK RPAVPKKAQT RK
Protein Neighborhood
Domains & Features
10 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q5T5Y3-1-unknown | MVDASG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q5T5Y3-1-unknown | MVDASG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt69223 | |||
| Q5T5Y3-279-unknown | MADSLY... | 279 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt69222 | |||
| Q5T5Y3-279-unknown | MADSLY... | 279 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt101669 | |||
| Q5T5Y3-431-unknown | SIQGED... | 431 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170873 | |||
| Q5T5Y3-431-unknown | SIQGED... | 431 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170872 | |||
| Q5T5Y3-431- | SIQGED... | 431 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
| Q5T5Y3-752- | FMGEAH... | 752 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
| Q5T5Y3-752-unknown | FMGEAH... | 752 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170876 | |||
| Q5T5Y3-752-unknown | FMGEAH... | 752 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170875 | |||
| Q5T5Y3-1255-unknown | GSADLV... | 1255 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170882 | |||
| Q5T5Y3-1255-unknown | GSADLV... | 1255 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170881 | |||
| Q5T5Y3-1255- | GSADLV... | 1255 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
| Q5T5Y3-1255- | GSADLV... | 1255 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
| Q5T5Y3-1255- | GSADLV... | 1255 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
| Q5T5Y3-1457- | SVAEYT... | 1457 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
| Q5T5Y3-1457-unknown | SVAEYT... | 1457 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170879 | |||
| Q5T5Y3-1457-unknown | SVAEYT... | 1457 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170878 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...AQTRK | 1602 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...AQTRK | 1602 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt64840 | |||
| ...AQTRK | 1602 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt64841 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|