Q5TAX3: Terminal uridylyltransferase 4 {ECO:0000305}

General Information

Protein names	- Terminal uridylyltransferase 4 {ECO:0000305} - TUTase 4 - 2.7.7.52 {ECO:0000269\|PubMed:19703396, ECO:0000269\|PubMed:31036859} - Zinc finger CCHC domain-containing protein 11
Gene names	ZCCHC11
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5TAX3

5 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEESKTLKSE NHEPKKNVIC EESKAVQVIG NQTLKARNDK SVKEIENSSP NRNSSKKNKQ
        70         80         90        100        110        120
NDICIEKTEV KSCKVNAANL PGPKDLGLVL RDQSHCKAKK FPNSPVKAEK ATISQAKSEK
       130        140        150        160        170        180
ATSLQAKAEK SPKSPNSVKA EKASSYQMKS EKVPSSPAEA EKGPSLLLKD MRQKTELQQI
       190        200        210        220        230        240
GKKIPSSFTS VDKVNIEAVG GEKCALQNSP RSQKQQTCTD NTGDSDDSAS GIEDVSDDLS
       250        260        270        280        290        300
KMKNDESNKE NSSEMDYLEN ATVIDESALT PEQRLGLKQA EERLERDHIF RLEKRSPEYT
       310        320        330        340        350        360
NCRYLCKLCL IHIENIQGAH KHIKEKRHKK NILEKQEESE LRSLPPPSPA HLAALSVAVI
       370        380        390        400        410        420
ELAKEHGITD DDLRVRQEIV EEMSKVITTF LPECSLRLYG SSLTRFALKS SDVNIDIKFP
       430        440        450        460        470        480
PKMNHPDLLI KVLGILKKNV LYVDVESDFH AKVPVVVCRD RKSGLLCRVS AGNDMACLTT
       490        500        510        520        530        540
DLLTALGKIE PVFIPLVLAF RYWAKLCYID SQTDGGIPSY CFALMVMFFL QQRKPPLLPC
       550        560        570        580        590        600
LLGSWIEGFD PKRMDDFQLK GIVEEKFVKW ECNSSSATEK NSIAEENKAK ADQPKDDTKK
       610        620        630        640        650        660
TETDNQSNAM KEKHGKSPLA LETPNRVSLG QLWLELLKFY TLDFALEEYV ICVRIQDILT
       670        680        690        700        710        720
RENKNWPKRR IAIEDPFSVK RNVARSLNSQ LVYEYVVERF RAAYRYFACP QTKGGNKSTV
       730        740        750        760        770        780
DFKKREKGKI SNKKPVKSNN MATNGCILLG ETTEKINAER EQPVQCDEMD CTSQRCIIDN
       790        800        810        820        830        840
NNLLVNELDF ADHGQDSSSL STSKSSEIEP KLDKKQDDLA PSETCLKKEL SQCNCIDLSK
       850        860        870        880        890        900
SPDPDKSTGT DCRSNLETES SHQSVCTDTS ATSCNCKATE DASDLNDDDN LPTQELYYVF
       910        920        930        940        950        960
DKFILTSGKP PTIVCSICKK DGHSKNDCPE DFRKIDLKPL PPMTNRFREI LDLVCKRCFD
       970        980        990       1000       1010       1020
ELSPPCSEQH NREQILIGLE KFIQKEYDEK ARLCLFGSSK NGFGFRDSDL DICMTLEGHE
      1030       1040       1050       1060       1070       1080
NAEKLNCKEI IENLAKILKR HPGLRNILPI TTAKVPIVKF EHRRSGLEGD ISLYNTLAQH
      1090       1100       1110       1120       1130       1140
NTRMLATYAA IDPRVQYLGY TMKVFAKRCD IGDASRGSLS SYAYILMVLY FLQQRKPPVI
      1150       1160       1170       1180       1190       1200
PVLQEIFDGK QIPQRMVDGW NAFFFDKTEE LKKRLPSLGK NTESLGELWL GLLRFYTEEF
      1210       1220       1230       1240       1250       1260
DFKEYVISIR QKKLLTTFEK QWTSKCIAIE DPFDLNHNLG AGVSRKMTNF IMKAFINGRK
      1270       1280       1290       1300       1310       1320
LFGTPFYPLI GREAEYFFDS RVLTDGELAP NDRCCRVCGK IGHYMKDCPK RKSLLFRLKK
      1330       1340       1350       1360       1370       1380
KDSEEEKEGN EEEKDSRDVL DPRDLHDTRD FRDPRDLRCF ICGDAGHVRR ECPEVKLARQ
      1390       1400       1410       1420       1430       1440
RNSSVAAAQL VRNLVNAQQV AGSAQQQGDQ SIRTRQSSEC SESPSYSPQP QPFPQNSSQS
      1450       1460       1470       1480       1490       1500
AAITQPSSQP GSQPKLGPPQ QGAQPPHQVQ MPLYNFPQSP PAQYSPMHNM GLLPMHPLQI
      1510       1520       1530       1540       1550       1560
PAPSWPIHGP VIHSAPGSAP SNIGLNDPSI IFAQPAARPV AIPNTSHDGH WPRTVAPNSL
      1570       1580       1590       1600       1610       1620
VNSGAVGNSE PGFRGLTPPI PWEHAPRPHF PLVPASWPYG LHQNFMHQGN ARFQPNKPFY
      1630       1640
TQDRCATRRC RERCPHPPRG NVSE

Isoforms

- Isoform 2 of Terminal uridylyltransferase 4

Sequence View

        10         20         30         40         50         60
MEESKTLKSE NHEPKKNVIC EESKAVQVIG NQTLKARNDK SVKEIENSSP NRNSSKKNKQ
        70         80         90        100        110        120
NDICIEKTEV KSCKVNAANL PGPKDLGLVL RDQSHCKAKK FPNSPVKAEK ATISQAKSEK
       130        140        150        160        170        180
ATSLQAKAEK SPKSPNSVKA EKASSYQMKS EKVPSSPAEA EKGPSLLLKD MRQKTELQQI
       190        200        210        220        230        240
GKKIPSSFTS VDKVNIEAVG GEKCALQNSP RSQKQQTCTD NTGDSDDSAS GIEDVSDDLS
       250        260        270        280        290        300
KMKNDESNKE NSSEMDYLEN ATVIDESALT PEQRLGLKQA EERLERDHIF RLEKRSPEYT
       310        320        330        340        350        360
NCRYLCKLCL IHIENIQGAH KHIKEKRHKK NILEKQEESE LRSLPPPSPA HLAALSVAVI
       370        380        390        400        410        420
ELAKEHGITD DDLRVRQEIV EEMSKVITTF LPECSLRLYG SSLTRFALKS SDVNIDIKFP
       430        440        450        460        470        480
PKMNHPDLLI KVLGILKKNV LYVDVESDFH AKVPVVVCRD RKSGLLCRVS AGNDMACLTT
       490        500        510        520        530        540
DLLTALGKIE PVFIPLVLAF RYWAKLCYID SQTDGGIPSY CFALMVMFFL QQRKPPLLPC
       550        560        570        580        590        600
LLGSWIEGFD PKRMDDFQLK GIVEEKFVKW ECNSSSATEK NSIAEENKAK ADQPKDDTKK
       610        620        630        640        650        660
TETDNQSNAM KEKHGKSPLA LETPNRVSLG QLWLELLKFY TLDFALEEYV ICVRIQDILT
       670        680        690        700        710        720
RENKNWPKRR IAIEDPFSVK RNVARSLNSQ LVYEYVVERF RAAYRYFACP QTKGGNKSTV
       730        740        750        760        770        780
DFKKREKGKI SNKKPVKSNN MATNGCILLG ETTEKINAER EQPVQCDEMD CTSQRCIIDN
       790        800        810        820        830        840
NNLLVNELDF ADHGQDSSSL STSKSSEIEP KLDKKQDDLA PSETCLKKEL SQCNCIDLSK
       850        860        870        880        890        900
SPDPDKSTGT DCRSNLETES SHQSVCTDTS ATSCNCKATE DASDLNDDDN LPTQELYYVF
       910        920        930        940        950        960
DKFILTSGKP PTIVCSICKK DGHSKNDCPE DFRKIDLKPL PPMTNRFREI LDLVCKRCFD
       970        980        990       1000       1010       1020
ELSPPCSEQH NREQILIGLE KFIQKEYDEK ARLCLFGSSK NGFGFRDSDL DICMTLEGHE
      1030       1040       1050       1060       1070       1080
NAEKLNCKEI IENLAKILKR HPGLRNILPI TTAKVPIVKF EHRRSGLEGD ISLYNTLAQH
      1090       1100       1110       1120       1130       1140
NTRMLATYAA IDPRVQYLGY TMKVFAKRCD IGDASRGSLS SYAYILMVLY FLQQRKPPVI
      1150       1160       1170       1180       1190       1200
PVLQEIFDGK QIPQRMVDGW NAFFFDKTEE LKKRLPSLGK NTESLGELWL GLLRFYTEEF
      1210       1220       1230       1240       1250       1260
DFKEYVISIR QKKLLTTFEK QWTSKCIAIE DPFDLNHNLG AGVSRKMTNF IMKAFINGRK
      1270       1280       1290       1300       1310       1320
LFGTPFYPLI GREAEYFFDS RVLTDGELAP NDRCCRVCGK IGHYMKDCPK RKSLLFRLKK
      1330       1340       1350       1360       1370       1380
KDSEEEKEGN EEEKDSRDVL DPRDLHDTRD FRDPRDLRCF ICGDAGHVRR ECPEVKLARQ
      1390       1400       1410       1420       1430       1440
RNSSVAAAQL VRNLVNAQQV AGSAQQQGDQ SIRTRQSSEC SESPSYSPQP QPFPQNSSQS
      1450       1460       1470       1480       1490       1500
AAITQPSSQP GSQPKLGPPQ QGAQPPHQVQ MPLYNFPQSP PAQYSPMHNM GLLPMHPLQI
      1510       1520       1530       1540       1550       1560
PAPSWPIHGP VIHSAPGSAP SNIGLNDPSI IFAQPAARPV AIPNTSHDGH WPRTVAPNSL
      1570       1580       1590       1600       1610       1620
VNSGAVGNSE PGFRGLTPPI PWEHAPRPHF PLVPASWPYG LHQNFMHQGN ARFQPNKPFY
      1630       1640
TQDRCATRRC RERCPHPPRG NVSE

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q5TAX3-1-unknown	MEESKT...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q5TAX3-1-unknown	MEESKT...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93445
Q5TAX3-221-unknown	NTGDSD...	221	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177018
Q5TAX3-221-	NTGDSD...	221		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q5TAX3-242-unknown	MKNDES...	242	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000435256
Q5TAX3-242-unknown	MKNDES...	242	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt130645
Q5TAX3-1159-unknown	GWNAFF...	1159	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000435700

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CKVNAA	77	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435568
...CKVNAA	77	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110175
...PKDLGL	87	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434367
...PKDLGL	87	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110173
...NTESLG	1185	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435256
...IGREAE	1274	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000433486
...MHNMGL	1491	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000433711
...DPSIIF	1531	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435700
...GNVSE	1644	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q5TAX3: Terminal uridylyltransferase 4 {ECO:0000305}

General Information

5

N-termini

7

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates