Q60854: Serpin B6

General Information

Protein names	- Serpin B6 - Placental thrombin inhibitor - Proteinase inhibitor 6 - PI-6
Gene names	Serpinb6
Organism	Mus musculus
Protease Family
Protease ID	I04.030
Chromosome location
UniProt ID	Q60854

3 N-termini

11 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDPLQEANGT FALNLLKILG EDSSKNVFLS PMSISSALAM VFMGAKGTTA SQMAQALALD
        70         80         90        100        110        120
KCSGNGGGDV HQGFQSLLTE VNKTGTQYLL RTANRLFGDK TCDLLASFKD SCLKFYEAEL
       130        140        150        160        170        180
EELDFQGATE ESRQHINTWV AKKTEDKIKE VLSPGTVNSD TSLVLVNAIY FKGNWEKQFN
       190        200        210        220        230        240
KEHTREMPFK VSKNEEKPVQ MMFKKSTFKM TYIGEIFTKI LLLPYVSSEL NMIIMLPDEH
       250        260        270        280        290        300
VELSTVEKEV TYEKFIEWTR LDKMDEEEVE VFLPKFKLEE NYNMNDALYK LGMTDAFGGR
       310        320        330        340        350        360
ADFSGMSSKQ GLFLSKVVHK AFVEVNEEGT EAAAATAGMM TVRCMRFTPR FCADHPFLFF
       370
IHHVKTNGIL FCGRFSSP

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 11 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q60854-1-Acetylation	MDPLQE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q60854-78-unknown	LTEVNK...	78		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30472
Q60854-78-unknown	LTEVNK...	78		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29140
Q60854-325-unknown	VNEEGT...	325		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30473

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GNGGGD	68	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000126287
...GDVHQG	72	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000131900
...GFQSLL	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30472
...GFQSLL	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29140
...YEAELE	120	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000126450
...VAKKTE	144	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000127224
...NSDTSL	162	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000130356
...HTREMP	187	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000126162
...FKVSKN	193	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000127768
...PYVSSE	228	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000132433
...KAFVEV	324	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30473
...RFSSP	378	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	77	QSLL.\|.LTEV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> SPB6_MOUSE @77
CATD_MOUSE	77	QSLL.\|.LTEV	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> SPB6_MOUSE @77
CATE_MOUSE	324	FVEV.\|.VNEE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> SPB6_MOUSE @324

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)