Q61072: Disintegrin and metalloproteinase domain-containing protein 9
| Protein names | - Disintegrin and metalloproteinase domain-containing protein 9 - ADAM 9 - 3.4.24.- - Meltrin-gamma - Metalloprotease/disintegrin/cysteine-rich protein 9 - Myeloma cell metalloproteinase |
|---|---|
| Gene names | Adam9 |
| Organism | Mus musculus |
| Protease Family | M12.209 |
| Protease ID | M12.209 |
| Chromosome location | |
| UniProt ID | Q61072 |
3
N-termini
2
C-termini
1
Cleavages
4
Substrates
Sequence
10 20 30 40 50 60
MGPRALSPLA SLRLRWLLAC GLLGPVLEAG RPDLEQTVHL SSYEIITPWR LTRERREALG
70 80 90 100 110 120
PSSQQISYVI QAQGKQHIIH LERNTDLLPN DFVVYTYDKE GSLLSDHPNV QSHCHYRGYV
130 140 150 160 170 180
EGVQNSAVAV SACFGLRGLL HLENASFGIE PLHNSSHFEH IFYPMDGIHQ EPLRCGVSNR
190 200 210 220 230 240
DTEKEGTQGD EEEHPSVTQL LRRRRAVLPQ TRYVELFIVV DKERYDMMGR NQTAVREEMI
250 260 270 280 290 300
RLANYLDSMY IMLNIRIVLV GLEIWTDRNP INIIGGAGDV LGNFVQWREK FLITRWRHDS
310 320 330 340 350 360
AQLVLKKGFG GTAGMAFVGT VCSRSHAGGI NVFGQITVET FASIVAHELG HNLGMNHDDG
370 380 390 400 410 420
RECFCGAKSC IMNSGASGSR NFSSCSAEDF EKLTLNKGGS CLLNIPKPDE AYSAPSCGNK
430 440 450 460 470 480
LVDPGEECDC GTAKECEVDP CCEGSTCKLK SFAECAYGDC CKDCQFLPGG SMCRGKTSEC
490 500 510 520 530 540
DVPEYCNGSS QFCPPDVFIQ NGYPCQNSKA YCYNGMCQYY DAQCQVIFGS KAKAAPRDCF
550 560 570 580 590 600
IEVNSKGDRF GNCGFSGSEY KKCATGNALC GKLQCENVQD MPVFGIVPAI IQTPSRGTKC
610 620 630 640 650 660
WGVDFQLGSD VPDPGMVNEG TKCDAGKICR NFQCVNASVL NYDCDIQGKC HGHGVCNSNK
670 680 690 700 710 720
NCHCEDGWAP PHCDTKGYGG SVDSGPTYNA KSTALRDGLL VFFFLIVPLV AAAIFLFIKR
730 740 750 760 770 780
DELRKTFRKK RSQMSDGRNQ ANVSRQPGDP SISRPPGGPN VSRPPGGPGV SRPPGGPGVS
790 800 810 820 830 840
RPPGGPGVSR PPPGHGNRFP VPTYAAKQPA QFPSRPPPPQ PKISSQGNLI PARPAPAPPL
YSSLT
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 4 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q61072-30-unknown | GRPDLE... | 30 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q61072-135-unknown | GLRGLL... | 135 | inferred from electronic annotation | unknown | TISdb | inferred from TISdb | |||
| Q61072-206-unknown | AVLPQT... | 206 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27885 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LRRRRA | 205 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27885 | |||
| ...YSSLT | 845 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ADAM9_MOUSE | 205 | RRRA.|.AVLP | inferred from experiment | unknown | MEROPS | Ishiura S | Koike H et al.:Membrane-anchored metalloprotea... (M12.209) | 10510302, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| SCF_MOUSE | 189 | PVAA.|.ASSL | inferred from experiment | unknown | MEROPS | Blobel CP | Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217) | 17344430, |
| SCF_MOUSE | 190 | VAAS.|.SSLR | inferred from experiment | unknown | MEROPS | Blobel CP | Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217) | 17344430, |
| SCF_MOUSE | 191 | AASS.|.SLRN | inferred from experiment | unknown | MEROPS | Blobel CP | Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217) | 17344430, |
| ADAM9_MOUSE | 205 | RRRA.|.AVLP | inferred from experiment | unknown | MEROPS | Ishiura S | Koike H et al.:Membrane-anchored metalloprotea... (M12.209) | 10510302, |