P20826: Kit ligand

General Information

Protein names	- Kit ligand - Hematopoietic growth factor KL - Mast cell growth factor - MGF - Steel factor - Stem cell factor - SCF - c-Kit ligand - Soluble KIT ligand - sKITLG
Gene names	Kitlg
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P20826

5 N-termini

4 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKKTQTWIIT CIYLQLLLFN PLVKTKEICG NPVTDNVKDI TKLVANLPND YMITLNYVAG
        70         80         90        100        110        120
MDVLPSHCWL RDMVIQLSLS LTTLLDKFSN ISEGLSNYSI IDKLGKIVDD LVLCMEENAP
       130        140        150        160        170        180
KNIKESPKRP ETRSFTPEEF FSIFNRSIDA FKDFMVASDT SDCVLSSTLG PEKDSRVSVT
       190        200        210        220        230        240
KPFMLPPVAA SSLRNDSSSS NRKAAKAPED SGLQWTAMAL PALISLVIGF AFGALYWKKK
       250        260        270
QSSLTRAVEN IQINEEDNEI SMLQQKEREF QEV

Isoforms

- Isoform 2 of Kit ligand

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 7 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P20826-1-unknown	MKKTQT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89009
P20826-26-unknown	KEICGN...	26	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P20826-26-unknown	KEICGN...	26	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114030
P20826-190-unknown	ASSLRN...	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27882
P20826-191-unknown	SSLRND...	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27843
P20826-191-unknown	SSLRND...	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27862
P20826-191-unknown	SSLRND...	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27865
P20826-191-unknown	SSLRND...	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27877
P20826-191-unknown	SSLRND...	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27883
P20826-191-unknown	SSLRND...	191	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P20826-191-unknown	SSLRND...	191	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P20826-192-unknown	SLRNDS...	192	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27884

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPPVAA	189	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27882
...PPVAAS	190	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PPVAAS	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27843
...PPVAAS	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27862
...PPVAAS	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27865
...PPVAAS	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27877
...PPVAAS	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27883
...PVAASS	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27884
...EFQEV	273	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EFQEV	273	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84627

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ADAM9_MOUSE	189	PVAA.\|.ASSL	inferred from experiment	unknown	MEROPS	Blobel CP	Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217)	17344430,
ADA17_MOUSE	190	VAAS.\|.SSLR	inferred from experiment	unknown	MEROPS	Blobel CP	Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217)	17344430,
ADA19_MOUSE	190	VAAS.\|.SSLR	inferred from experiment	unknown	MEROPS	Blobel CP	Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217)	17344430,
ADA33_MOUSE	190	VAAS.\|.SSLR	inferred from experiment	unknown	MEROPS	Umland SP	Zou J et al.:Catalytic activity of human ADA... (M12.244)	14676211,
ADAM8_MOUSE	190	VAAS.\|.SSLR	inferred from experiment	unknown	MEROPS	Blobel CP	Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217)	17344430,
ADAM9_MOUSE	190	VAAS.\|.SSLR	inferred from experiment	unknown	MEROPS	Blobel CP	Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217)	17344430,
ADAM9_MOUSE	191	AASS.\|.SLRN	inferred from experiment	unknown	MEROPS	Blobel CP	Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217)	17344430,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)