O35674: Disintegrin and metalloproteinase domain-containing protein 19
Protein names | - Disintegrin and metalloproteinase domain-containing protein 19 - ADAM 19 - 3.4.24.- - Meltrin-beta |
---|---|
Gene names | Adam19 |
Organism | Mus musculus |
Protease Family | M12.214 |
Protease ID | M12.214 |
Chromosome location | |
UniProt ID | O35674 |
2
N-termini
1
C-termini
0
Cleavages
4
Substrates
Sequence
10 20 30 40 50 60
MPGRAGVARF CLLALALQLH WPLAACEPGW TTRGSQEGSP PLQHELIIPQ WRTSESPGRG
70 80 90 100 110 120
KHPLRAELRV MAEGRELILD LEKNEHLFAP AYTETCYTAS GNPQTSTLKS EDHCFYHGTV
130 140 150 160 170 180
RDVDESSVTL STCRGIRGLI IVRSNLSYII EPVPNSDSQH RIYRSEHLTL PPGNCGFEHS
190 200 210 220 230 240
GPTSKDWALQ FTHQTKKQPR RMKREDLHSM KYVELYLVAD YAEFQKNRHD QDATKRKLME
250 260 270 280 290 300
IANYVDKFYR SLNIRIALVG LEVWTHGDKC EVSENPYSTL WSFLSWRRKL LAQKSHDNAQ
310 320 330 340 350 360
LITGRSFQGT TIGLAPLMAM CSVYQSGGVS MDHSENAIGV ASTVAHEIGH NFGMSHDSAH
370 380 390 400 410 420
CCSASAADGG CIMAAATGHP FPKVFSWCNR KELDRYLQTG GGMCLSNMPD TRTLYGGRRC
430 440 450 460 470 480
GNGYLEDGEE CDCGEEEECK NPCCNASNCT LKEGAECAHG SCCHQCKLVA PGTQCREQVR
490 500 510 520 530 540
QCDLPEFCTG KSPHCPTNYY QMDGTPCEGG QAYCYNGMCL TYQEQCQQLW GPGARPALDL
550 560 570 580 590 600
CFERVNAAGD TYGNCGKGLN GQYRKCSPRD AKCGKIQCQS TQARPLESNA VSIDTTITLN
610 620 630 640 650 660
GRRIHCRGTH VYRGPEEEEG EGDMLDPGLV MTGTKCGHNH ICFEGQCRNT SFFETEGCGK
670 680 690 700 710 720
KCNGHGVCNN NKNCHCFPGW SPPFCNTPGD GGSVDSGPLP PKSVGPVIAG VFSALFVLAV
730 740 750 760 770 780
LVLLCHCYRQ SHKLGKPSAL PFKLRHQFSC PFRVSQSGGT GHANPTFKLQ TPQGKRKVTN
790 800 810 820 830 840
TPESLRKPSH PPPRPPPDYL RVESPPAPLP AHLNRAAGSS PEAGARIERK ESARRPPPSR
850 860 870 880 890 900
PMPPAPNCLL SQDFSRPRPP QKALPANPVP GQRTGPRSGG TSLLQPPTSG PQPPRPPAVP
910 920
VPKLPEYRSQ RVGAIISSKI
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 4 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O35674-27-unknown | EPGWTT... | 27 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O35674-205-unknown | EDLHSM... | 205 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O35674-205-unknown | EDLHSM... | 205 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...ISSKI | 920 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
TNF11-Isoform3_MOUSE | 21 | PQRF.|.FSGA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC27859 | ||
TNF11-Isoform2_MOUSE | 109 | PQRF.|.FSGA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC27859 | ||
TNF11_MOUSE | 138 | PQRF.|.FSGA | inferred from experiment | unknown | MEROPS | Blobel CP | Chesneau V et al.:Catalytic properties of ADAM19.... (M12.214) | 12682046, |
SCF_MOUSE | 190 | VAAS.|.SSLR | inferred from experiment | unknown | MEROPS | Blobel CP | Kawaguchi N et al.:Different ADAMs have distinct i... (M12.217) | 17344430, |