TopFIND 4.0

Q923W9: Disintegrin and metalloproteinase domain-containing protein 33

General Information

Protein names
- Disintegrin and metalloproteinase domain-containing protein 33
- ADAM 33
- 3.4.24.-
Gene names Adam33
Organism Mus musculus
Protease Family M12.244
Protease ID M12.244
Chromosome location
UniProt ID Q923W9

3

N-termini

1

C-termini

0

Cleavages

1

Substrates

Sequence

        10         20         30         40         50         60 
MGSRCGRPGG SPVLLLLPLL LPSCPLRSAR MFPGNAHGEL VTPHWILEGR LWLKVTLEEP 
        70         80         90        100        110        120 
ILKPDSVLVA LEAEGQDLLL ELEKKHKLLA PGYTETHYRP DGHPVVLSPN HTDHCQYHGR 
       130        140        150        160        170        180 
VRGFRESWVV LSTCSGMSGL IVLSSKVSYY LQPRTPGDTK DFPTHEIFRM EQLFTWRGVQ 
       190        200        210        220        230        240 
RDKNSQYKAG MASLPHVPQS RVRREARRSP RYLELYIVAD HTLFLLQHQN LNHTRQRLLE 
       250        260        270        280        290        300 
VANCVDQILR TLDIQLVLTG LEVWTEQDLS RITQDANETL WAFLQWRRGV WARRPHDSTQ 
       310        320        330        340        350        360 
LLTGRTFQGT TVGLAPVEGI CRAESSGGVS TDHSELPIGT AATMAHEIGH SLGLHHDPEG 
       370        380        390        400        410        420 
CCVQADAEQG GCVMEAATGH PFPRVFSACS RRQLRTFFRK GGGPCLSNTS APGLLVLPSR 
       430        440        450        460        470        480 
CGNGFLEAGE ECDCGSGQKC PDPCCFAHNC SLRAGAQCAH GDCCARCLLK SAGTPCRPAA 
       490        500        510        520        530        540 
TDCDLPEFCT GTSPYCPADV YLLDGSPCAE GRGYCLDGWC PTLEQQCQQL WGPGSKPAPE 
       550        560        570        580        590        600 
PCFQQMNSMG NSQGNCGQDH KGSFLPCAQR DALCGKLLCQ GGEPNPLVPH IVTMDSTILL 
       610        620        630        640        650        660 
EGREVVCRGA FVLPDSHLDQ LDLGLVEPGT GCGPRMVCQD RHCQNATSQE LERCLTACHN 
       670        680        690        700        710        720 
GGVCNSNRNC HCAAGWAPPF CDKPGLGGSV DSGPAQSANR DAFPLAMLLS FLLPLLPGAG 
       730        740        750        760        770        780 
LAWCYYQLPT FCHRRGLCCR RDPLWNRDIP LGSVHPVEFG SIITGEPSPP PPWTSCQQRS 
       790    
HPPSLDLLSD PANSELT

Isoforms

- Isoform 2 of Disintegrin and metalloproteinase domain-containing protein 33

Sequence View

        10         20         30         40         50         60 
MGSRCGRPGG SPVLLLLPLL LPSCPLRSAR MFPGNAHGEL VTPHWILEGR LWLKVTLEEP 
        70         80         90        100        110        120 
ILKPDSVLVA LEAEGQDLLL ELEKKHKLLA PGYTETHYRP DGHPVVLSPN HTDHCQYHGR 
       130        140        150        160        170        180 
VRGFRESWVV LSTCSGMSGL IVLSSKVSYY LQPRTPGDTK DFPTHEIFRM EQLFTWRGVQ 
       190        200        210        220        230        240 
RDKNSQYKAG MASLPHVPQS RVRREARRSP RYLELYIVAD HTLFLLQHQN LNHTRQRLLE 
       250        260        270        280        290        300 
VANCVDQILR TLDIQLVLTG LEVWTEQDLS RITQDANETL WAFLQWRRGV WARRPHDSTQ 
       310        320        330        340        350        360 
LLTGRTFQGT TVGLAPVEGI CRAESSGGVS TDHSELPIGT AATMAHEIGH SLGLHHDPEG 
       370        380        390        400        410        420 
CCVQADAEQG GCVMEAATGH PFPRVFSACS RRQLRTFFRK GGGPCLSNTS APGLLVLPSR 
       430        440        450        460        470        480 
CGNGFLEAGE ECDCGSGQKC PDPCCFAHNC SLRAGAQCAH GDCCARCLLK SAGTPCRPAA 
       490        500        510        520        530        540 
TDCDLPEFCT GTSPYCPADV YLLDGSPCAE GRGYCLDGWC PTLEQQCQQL WGPGSKPAPE 
       550        560        570        580        590        600 
PCFQQMNSMG NSQGNCGQDH KGSFLPCAQR DALCGKLLCQ GGEPNPLVPH IVTMDSTILL 
       610        620        630        640        650        660 
EGREVVCRGA FVLPDSHLDQ LDLGLVEPGT GCGPRMVCQD RHCQNATSQE LERCLTACHN 
       670        680        690        700        710        720 
GGVCNSNRNC HCAAGWAPPF CDKPGLGGSV DSGPAQSANR DAFPLAMLLS FLLPLLPGAG 
       730        740        750        760        770        780 
LAWCYYQLPT FCHRRGLCCR RDPLWNRDIP LGSVHPVEFG SIITGEPSPP PPWTSCQQRS 
       790    
HPPSLDLLSD PANSELT



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 1 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NSELT 797 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...NSELT 797 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61937

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates