TopFIND 4.0

Q61129: Complement factor I

General Information

Protein names
- Complement factor I
- 3.4.21.45
- C3B/C4B inactivator
- Complement factor I heavy chain
- Complement factor I light chain
Gene names Cfi
Organism Mus musculus
Protease Family S01.199
Protease ID S01.199
Chromosome location
UniProt ID Q61129

4

N-termini

2

C-termini

0

Cleavages

4

Substrates

Sequence

        10         20         30         40         50         60 
MKLAHLSLFL LALHLSSSRS PSASDLPQEE LVDQKCLLQK YTHRSCNKVF CQPWQRCIEG 
        70         80         90        100        110        120 
TCICKLPYQC PRAGTPVCAM NGRSYPTYCH QKSFECLHPE IKFSHNGTCA AEGKFNVSLI 
       130        140        150        160        170        180 
YGRTKTEGLV QVKLVDQDER MFICKNSWSM AEANVACVDL GFPLGVRDIQ GSFNISGNLH 
       190        200        210        220        230        240 
INDTECLHVH CRGVETSLAE CAFTKRRTEL SNGLAGVVCY KQDADFPTSL SFQCVNGKHI 
       250        260        270        280        290        300 
PQEKACNGVN DCGDQSDELC CKGCRGNASL CKSGVCIPDQ YKCNGEVDCI TGEDESRCEE 
       310        320        330        340        350        360 
DRQQNIPKGL ARSAQGEAEI ETEETEMLTP GMDNERKRIK SLLPKLSCGV KRNTHTRRKR 
       370        380        390        400        410        420 
VIGGKPANVG DYPWQVAIKD GQRITCGGIY IGGCWILTAA HCVRPSRAHS YQVWTALLDW 
       430        440        450        460        470        480 
LKPNSQLGIQ TVKRVIVHEK YNGATFQNDI ALIEMKMHTG KKECELPNSV PACVPWSPYL 
       490        500        510        520        530        540 
FQPNDRCIIS GWGRGKDNQK VYSLRWGEVD LIGNCSQFYP DRYYEKEMQC AGTRDGSIDA 
       550        560        570        580        590        600 
CKGDSGGPLV CEDINNVTYV WGIVSWGENC GKPEFPGVYT RVANYFDWIS YHVGRSLVSQ 
   
HNV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 4 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RNTHTR 356 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SQHNV 603 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates