Q61166: Microtubule-associated protein RP/EB family member 1

General Information

Protein names	- Microtubule-associated protein RP/EB family member 1 - APC-binding protein EB1 - End-binding protein 1 - EB1
Gene names	Mapre1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61166

6 N-termini

3 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVNVYSTSV TSDNLSRHDM LAWINESLQL NLTKIEQLCS GAAYCQFMDM LFPGSIALKK
        70         80         90        100        110        120
VKFQAKLEHE YIQNFKILQA GFKRMGVDKI IPVDKLVKGK FQDNFEFVQW FKKFFDANYD
       130        140        150        160        170        180
GKEYDPVAAR QGQETAVAPS LVAPALSKPK KPLGSSTAAP QRPIATQRTT AAPKAGPGMV
       190        200        210        220        230        240
RKNPGVGNGD DEAAELMQQV KVLKLTVEDL EKERDFYFGK LRNIELICQE NEGENDPVLQ
       250        260
RIVDILYATD EGFVIPDEGG PQEEQEEY

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q61166-2-unknown	MAVNVY...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q61166-2-Acetylation	AVNVYS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q61166-5-unknown	VYSTSV...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33935
Q61166-171-unmodified	AAPKAG...	171			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q61166-200-unknown	VKVLKL...	200		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33936
Q61166-205-unknown	LTVEDL...	205		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33937

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ELMQQV	199	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33936
...VKVLKL	204	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33937
...EQEEY	268	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	4	AVNV.\|.VYST	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	199	MQQV.\|.VKVL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	204	VLKL.\|.LTVE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)