Q61233: Plastin-2

General Information

Protein names	- Plastin-2 - 65 kDa macrophage protein - L-plastin - Lymphocyte cytosolic protein 1 - LCP-1 - pp65
Gene names	Lcp1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61233

15 N-termini

17 C-termini

16 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MARGSVSDEE MMELREAFAK VDTDGNGYIS CNELNDLFKA ACLPLPGYRV REITENLMAT
        70         80         90        100        110        120
GDLDQDGKIS FDEFIKVFHG LKSTEVAKTF RKAINKKEGI CAIGGTSEQS SVGTQHSYSE
       130        140        150        160        170        180
EEKYAFVNWI NKALENDPDC RHVIPMNPNT DDLFNAVGDG IVLCKMINLS VPDTIDERTI
       190        200        210        220        230        240
NKKKLTPFTI QENLNLALNS ASAIGCHVVN IGAEDLKEGK PYLVLGLLWQ VIKIGLFADI
       250        260        270        280        290        300
ELSRNEALIA LLREGESLED LMKLSPEELL LRWANYHLEN AGCTKITNFS TDIKDSKAYY
       310        320        330        340        350        360
HLLEQVAPKG DEEGIPAVVI DMSGLREKDD IQRAECMLQQ AERLGCRQFV TATDVVRGNP
       370        380        390        400        410        420
KLNLAFIANL FNKYPALHKP ENQDIDWGAL EGETREERTF RNWMNSLGVN PRVNHLYSDL
       430        440        450        460        470        480
SDALVIFQLY EKIKVPVDWN RVNKPPYPKL GGNMKKLENC NYAVDLGKNQ AKFSLVGIAG
       490        500        510        520        530        540
QDLNEGNRTL TLALVWQLMR RYTLNILEDI GGGQKVNDDI IVNWVNTTLK EAQKSSSIAS
       550        560        570        580        590        600
FKDPKISTSL PVLDLIDAIQ PGSINYDLLK TENLDDEEKL NNAKYAISMA RKIGARVYAL
       610        620
PEDLVEVNPK MVMTVFACLM GKGMKRV

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

15 N-termini - 17 C-termini - 16 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q61233-2-unknown	MARGSV...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q61233-2-unknown	MARGSV...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61233-2-Acetylation	ARGSVS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61233-2-Acetylation	ARGSVS...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q61233-38-unknown	FKAACL...	38		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29148
Q61233-130-unknown	INKALE...	130		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29149
Q61233-164-unknown	CKMINL...	164		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29150
Q61233-349-unknown	FVTATD...	349		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30495
Q61233-350-unknown	VTATDV...	350		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30496
Q61233-463-unknown	AVDLGK...	463		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30497
Q61233-476-unknown	VGIAGQ...	476		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30498
Q61233-478-unknown	IAGQDL...	478		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30499
Q61233-478-unknown	IAGQDL...	478		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29151
Q61233-569-unknown	LKTENL...	569		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30500
Q61233-569-unknown	LKTENL...	569		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29152
Q61233-575-unknown	DDEEKL...	575		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29153
Q61233-614-unknown	TVFACL...	614		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30501
Q61233-617-unknown	ACLMGK...	617		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30502
Q61233-617-unknown	ACLMGK...	617		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29154
Q61233-618-unknown	CLMGKG...	618		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30503

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ELNDLF	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29148
...DEFIKV	76	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118721
...KEGICA	101	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117984
...ICAIGG	104	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116033
...AFVNWI	129	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29149
...DGIVLC	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29150
...LGCRQF	348	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30495
...GCRQFV	349	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30496
...ENCNYA	462	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30497
...AKFSLV	475	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30498
...FSLVGI	477	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30499
...FSLVGI	477	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29151
...INYDLL	568	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30500
...INYDLL	568	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29152
...KTENLD	574	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29153
...PKMVMT	613	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30501
...VMTVFA	616	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30502
...VMTVFA	616	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29154
...MTVFAC	617	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30503
...GMKRV	627	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATD_MOUSE	37	NDLF.\|.FKAA	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PLSL_MOUSE @37
CATD_MOUSE	129	VNWI.\|.INKA	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PLSL_MOUSE @129
CATD_MOUSE	163	IVLC.\|.CKMI	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PLSL_MOUSE @163
CATE_MOUSE	348	CRQF.\|.FVTA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @348
CATE_MOUSE	349	RQFV.\|.VTAT	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @349
CATE_MOUSE	462	CNYA.\|.AVDL	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @462
CATE_MOUSE	475	FSLV.\|.VGIA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @475
CATE_MOUSE	477	LVGI.\|.IAGQ	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @477
CATD_MOUSE	477	LVGI.\|.IAGQ	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PLSL_MOUSE @477
CATE_MOUSE	568	YDLL.\|.LKTE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @568
CATD_MOUSE	568	YDLL.\|.LKTE	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PLSL_MOUSE @568
CATD_MOUSE	574	ENLD.\|.DDEE	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PLSL_MOUSE @574
CATE_MOUSE	613	MVMT.\|.TVFA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @613
CATE_MOUSE	616	TVFA.\|.ACLM	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @616
CATD_MOUSE	616	TVFA.\|.ACLM	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PLSL_MOUSE @616
CATE_MOUSE	617	VFAC.\|.CLMG	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PLSL_MOUSE @617

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)