Q61599: Rho GDP-dissociation inhibitor 2

General Information

Protein names	- Rho GDP-dissociation inhibitor 2 - Rho GDI 2 - D4 - Rho-GDI beta
Gene names	Arhgdib
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61599

13 N-termini

8 C-termini

11 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTEKDAQPQL EEADDDLDSK LNYKPPPQKS LKELQEMDKD DESLTKYKKT LLGDVPVVAD
        70         80         90        100        110        120
PTVPNVTVTR LSLVCDSAPG PITMDLTGDL EALKKDTFVL KEGIEYRVKI NFKVNKDIVS
       130        140        150        160        170        180
GLKYVQHTYR TGMRVDKATF MVGSYGPRPE EYEFLTPVEE APKGMLARGT YHNKSFFTDD
       190        200
DKQDHLTWEW NLAIKKDWTE

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

13 N-termini - 8 C-termini - 11 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
Q61599-2-unknown	MTEKDA...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q61599-2-unknown	MTEKDA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61599-2-Acetylation	TEKDAQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61599-2-Acetylation	TEKDAQ...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q61599-49-unmodified	KTLLGD...	49			unknown		Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q61599-50-unmodified	TLLGDV...	50			unknown		Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q61599-52-unknown	LGDVPV...	52		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30515
Q61599-52-unmodified	LGDVPV...	52			unknown		Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q61599-53-unmodified	GDVPVV...	53			unknown		Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q61599-54-unmodified	DVPVVA...	54			unknown		Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q61599-99-unknown	VLKEGI...	99		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30516
Q61599-99-unknown	VLKEGI...	99		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29161
Q61599-101-unknown	KEGIEY...	101		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30517
Q61599-101-unknown	KEGIEY...	101		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29162
Q61599-153-unknown	EFLTPV...	153		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30518
Q61599-153-unknown	EFLTPV...	153		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29163
Q61599-154-unknown	FLTPVE...	154		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30519
Q61599-154-unknown	FLTPVE...	154		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29164
Q61599-155-unknown	LTPVEE...	155		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30520
Q61599-155-unknown	LTPVEE...	155		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29165

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KYKKTL	50	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120047
...YKKTLL	51	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30515
...KKDTFV	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30516
...KKDTFV	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29161
...DTFVLK	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30517
...DTFVLK	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29162
...RPEEYE	152	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30518
...RPEEYE	152	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29163
...PEEYEF	153	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30519
...PEEYEF	153	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29164
...EEYEFL	154	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30520
...EEYEFL	154	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29165
...KDWTE	200	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	51	KTLL.\|.LGDV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> GDIR2_MOUSE @51
CATE_MOUSE	98	DTFV.\|.VLKE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> GDIR2_MOUSE @98
CATD_MOUSE	98	DTFV.\|.VLKE	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> GDIR2_MOUSE @98
CATE_MOUSE	100	FVLK.\|.KEGI	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> GDIR2_MOUSE @100
CATD_MOUSE	100	FVLK.\|.KEGI	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> GDIR2_MOUSE @100
CATE_MOUSE	152	EEYE.\|.EFLT	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> GDIR2_MOUSE @152
CATD_MOUSE	152	EEYE.\|.EFLT	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> GDIR2_MOUSE @152
CATE_MOUSE	153	EYEF.\|.FLTP	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> GDIR2_MOUSE @153
CATD_MOUSE	153	EYEF.\|.FLTP	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> GDIR2_MOUSE @153
CATE_MOUSE	154	YEFL.\|.LTPV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> GDIR2_MOUSE @154
CATD_MOUSE	154	YEFL.\|.LTPV	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> GDIR2_MOUSE @154

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)