Q61768: Kinesin-1 heavy chain

General Information

Protein names	- Kinesin-1 heavy chain - Conventional kinesin heavy chain - Ubiquitous kinesin heavy chain - UKHC
Gene names	Kif5b
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61768

4 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADPAECNIK VMCRFRPLNE SEVNRGDKYV AKFQGEDTVM IASKPYAFDR VFQSSTSQEQ
        70         80         90        100        110        120
VYNDCAKKIV KDVLEGYNGT IFAYGQTSSG KTHTMEGKLH DPEGMGIIPR IVQDIFNYIY
       130        140        150        160        170        180
SMDENLEFHI KVSYFEIYLD KIRDLLDVSK TNLSVHEDKN RVPYVKGCTE RFVCSPDEVM
       190        200        210        220        230        240
DTIDEGKSNR HVAVTNMNEH SSRSHSIFLI NVKQENTQTE QKLSGKLYLV DLAGSEKVSK
       250        260        270        280        290        300
TGAEGAVLDE AKNINKSLSA LGNVISALAE GSTYVPYRDS KMTRILQDSL GGNCRTTIVI
       310        320        330        340        350        360
CCSPSSYNES ETKSTLLFGQ RAKTIKNTVC VNVELTAEQW KKKYEKEKEK NKTLRNTIQW
       370        380        390        400        410        420
LENELNRWRN GETVPIDEQF DKEKANLEAF TADKDIAITS DKPAAAVGMA GSFTDAERRK
       430        440        450        460        470        480
CEEELAKLYK QLDDKDEEIN QQSQLVEKLK TQMLDQEELL ASTRRDQDNM QAELNRLQAE
       490        500        510        520        530        540
NDASKEEVKE VLQALEELAV NYDQKSQEVE DKTKEYELLS DELNQKSATL ASIDAELQKL
       550        560        570        580        590        600
KEMTNHQKKR AAEMMASLLK DLAEIGIAVG NNDVKQPEGT GMIDEEFTVA RLYISKMKSE
       610        620        630        640        650        660
VKTMVKRCKQ LESTQTESNK KMEENEKELA ACQLRISQHE AKIKSLTEYL QNVEQKKRQL
       670        680        690        700        710        720
EESVDSLGEE LVQLRAQEKV HEMEKEHLNK VQTANEVKQA VEQQIQSHRE THQKQISSLR
       730        740        750        760        770        780
DEVEAKEKLI TDLQDQNQKM VLEQERLRVE HERLKATDQE KSRKLHELTV MQDRREQARQ
       790        800        810        820        830        840
DLKGLEETVA KELQTLHNLR KLFVQDLATR VKKSAEVDSD DTGGSAAQKQ KISFLENNLE
       850        860        870        880        890        900
QLTKVHKQLV RDNADLRCEL PKLEKRLRAT AERVKALESA LKEAKENASR DRKRYQQEVD
       910        920        930        940        950        960
RIKEAVRSKN MARRGHSAQI AKPIRPGQHP AASPTHPGTV RGGGSFVQNN QPVGLRGGGG

KQS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q61768-2-unknown	MADPAE...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q61768-2-unknown	MADPAE...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61768-2-Acetylation	ADPAEC...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61768-2-Acetylation	ADPAEC...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q61768-268-unknown	LAEGST...	268		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33962
Q61768-947-unknown	VQNNQP...	947		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30531

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NVISAL	267	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33962
...QTESNK	619	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000130750
...GGGSFV	946	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30531
...GGKQS	963	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	267	ISAL.\|.LAEG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	946	GSFV.\|.VQNN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> KINH_MOUSE @946

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)