Q61792: LIM and SH3 domain protein 1

General Information

Protein names	- LIM and SH3 domain protein 1 - LASP-1 - Metastatic lymph node gene 50 protein - MLN 50
Gene names	Lasp1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61792

6 N-termini

13 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNPNCARCGK IVYPTEKVNC LDKYWHKACF HCETCKMTLN MKNYKGYEKK PYCNAHYPKQ
        70         80         90        100        110        120
SFTMVADTPE NLRLKQQSEL QSQVRYKEEF EKNKGKGFSV VADTPELQRI KKTQDQISNI
       130        140        150        160        170        180
KYHEEFEKSR MGPSGGEGVE PERREAQDSS SYRRPTEQQQ PQPHHIPTSA PVYQQPQQQQ
       190        200        210        220        230        240
MTSSYGGYKE PAAPVSIQRS APGGGGKRYR AVYDYSAADE DEVSFQDGDT IVNVQQIDDG
       250        260
WMYGTVERTG DTGMLPANYV EAI

Isoforms

Sequence View

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 13 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q61792-1-Acetylation	MNPNCA...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61792-37-unknown	MTLNMK...	37		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123165
Q61792-37-unknown	MTLNMK...	37		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120645
Q61792-37-unknown	MTLNMK...	37		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121907
Q61792-37-unknown	MTLNMK...	37		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000114306
Q61792-37-unknown	MTLNMK...	37		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115308
Q61792-37-unknown	MTLNMK...	37		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000127792
Q61792-37-unknown	MTLNMK...	37		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123050
Q61792-37-unknown	MTLNMK...	37		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120458
Q61792-64-unknown	MVADTP...	64		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119538
Q61792-65-unknown	VADTPE...	65		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30533
Q61792-99-unknown	SVVADT...	99		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30534
Q61792-120-unknown	IKYHEE...	120		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33963

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YWHKAC	28	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116102
...QSFTMV	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30533
...ELQSQV	83	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120458
...KGKGFS	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30534
...VADTPE	105	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000114306
...ADTPEL	106	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000127792
...QDQISN	118	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119538
...QDQISN	118	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33963
...KYHEEF	125	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121907
...MGPSGG	135	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120645
...GGEGVE	139	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123165
...PQPHHI	165	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115308
...ADEDEV	222	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123050
...YVEAI	263	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	64	FTMV.\|.VADT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> LASP1_MOUSE @64
CATE_MOUSE	98	KGFS.\|.SVVA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> LASP1_MOUSE @98
MMP2_MOUSE	119	ISNI.\|.IKYH	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)