Q62433: Protein NDRG1

General Information

Protein names	- Protein NDRG1 - N-myc downstream-regulated gene 1 protein - Protein Ndr1
Gene names	Ndrg1
Organism	Mus musculus
Protease Family
Protease ID	S33.987
Chromosome location
UniProt ID	Q62433

4 N-termini

8 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSRELHDVDL AEVKPLVEKG ESITGLLQEF DVQEQDIETL HGSLHVTLCG TPKGNRPVIL
        70         80         90        100        110        120
TYHDIGMNHK TCYNPLFNSE DMQEITQHFA VCHVDAPGQQ DGAPSFPVGY MYPSMDQLAE
       130        140        150        160        170        180
MLPGVLHQFG LKSVIGMGTG AGAYILTRFA LNNPEMVEGL VLMNVNPCAE GWMDWAASKI
       190        200        210        220        230        240
SGWTQALPDM VVSHLFGKEE IHNNVEVVHT YRQHILNDMN PSNLHLFISA YNSRRDLEIE
       250        260        270        280        290        300
RPMPGTHTVT LQCPALLVVG DNSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK
       310        320        330        340        350        360
LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLEGT RSRSHTSEGP RSRSHTSEGS
       370        380        390
RSRSHTSEDA RLNITPNSGA TGNNAGPKSM EVSC

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 8 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q62433-2-unknown	MSRELH...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q62433-2-unknown	MSRELH...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q62433-2-Acetylation	SRELHD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q62433-2-Acetylation	SRELHD...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q62433-227-unknown	FISAYN...	227		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30554
Q62433-309-unknown	VQGMGY...	309		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30555
Q62433-309-unknown	VQGMGY...	309		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29176

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HKTCYN	73	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000126091
...LNNPEM	155	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000130584
...NPEMVE	157	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000127302
...EGWMDW	174	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000127075
...EGWMDW	174	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000126985
...SNLHLF	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30554
...AFKYFV	308	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30555
...AFKYFV	308	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29176
...TRLMRS	325	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000127099
...MEVSC	394	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	226	LHLF.\|.FISA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> NDRG1_MOUSE @226
CATE_MOUSE	308	KYFV.\|.VQGM	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> NDRG1_MOUSE @308
CATD_MOUSE	308	KYFV.\|.VQGM	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> NDRG1_MOUSE @308

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)