Q6GQX2: Nck-associated protein 5-like

General Information

Protein names	- Nck-associated protein 5-like - Centrosomal protein of 169 kDa {ECO:0000250\|UniProtKB:Q9HCH0} - Cep169 {ECO:0000250\|UniProtKB:Q9HCH0}
Gene names	Nckap5l
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6GQX2

2 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDQPAGGTGK LRASAGEDDS MELSTCQELL HRLRELEAEN SALAQANENQ RETYERCLDE
        70         80         90        100        110        120
VANHVVQALL NQKDLREECI KLKKRVFDLE RQNQVLSALL QQKLQLTANS LPQIPLTPLQ
       130        140        150        160        170        180
PPSERPTSPA PNVSEGPATS LPSGLCAGQR EVCWEQQLRP GGPGPPATPP PALDALSPFL
       190        200        210        220        230        240
RKKAQILEVL RALEETDPLL LCSPATPWRP TGQGPGSPEP INGEPCGPPQ PEPSPWAPYL
       250        260        270        280        290        300
LLGPGSLGAL LHWERVLGGP GEEEGIRQPW ASSRAPPSAQ GPSSGPHCAP GSSSSSSSDE
       310        320        330        340        350        360
AGDPNEAPSP DTLLGALARK QLNLGQLLGD TETYLQAFLA GATGPLSGDQ PGPGKPNSPD
       370        380        390        400        410        420
PGPPQVSKSK GLPKSAWGAS TPEATRLGFG ATSEGQGPLP FLSMFMGAGD APLGSRPGHP
       430        440        450        460        470        480
HSSSQVKSKL QIGPPSPGDA QGPLLPSPAR GLKFLKLPPA SEKVPSPGGP QLSPQLPRSS
       490        500        510        520        530        540
RIPCRNSGSD GSPSPLLARR GLGGGELSPE GAQGLPGSPL PCSAMPDSAQ LRPSQSTVST
       550        560        570        580        590        600
ALSPGPVVSP CFENILDLSR STFRGSPPEP PPSPLQVPTY PQLTLEVPQT PEVLRSPGAP
       610        620        630        640        650        660
SPGLPESCPY SGPQEKSMDR AGSESPHASR RTPGGSSKKP GQGSGRRPGD PSHTPLRDRL
       670        680        690        700        710        720
AALGKLKTGP EGPLGPEKNG VPARSSAEKA RALVRSGECA GDVPPSARPL EQPEAKGIFR
       730        740        750        760        770        780
GAVALGTSSL KQQEPGLTDP GARVYSSHSM GARVDLEPIS PRSCLTKVEL AKSRLAGALC
       790        800        810        820        830        840
PQMPRTPAKV PTSAPSLGKP KSPHSSPTKL PSKSPTKVVP RPVVPLGTKE PPKPDKVKGP
       850        860        870        880        890        900
PWADCGSTVG QPTSPVAGPA DPSQGSEGPA PHSAIEEKVM KGIEENVLRL QGQERTPGSE
       910        920        930        940        950        960
AKHRNTSSIA SWFGLKKSKL PALNRRTEAT KNKDGAGGGS PLRKEVKTEA RKLEAESLNI
       970        980        990       1000       1010       1020
SKLMAKAEDL RRALEEEKAY LSRARPRPGG PATVPSPGLG QAQGQLAGMY QGADTFMQQL
      1030       1040       1050       1060       1070       1080
LNRVDGKELP PKSWREPKPE YGDFQPVSTD PKSPWPACGP RNGLVGPLQG CGKPGKPSSE
      1090       1100       1110       1120       1130       1140
PGRREEMPSE DSLAEPVSTT HFTACGSLTR TLDSGIGTFP PPDHSSSGTP SKNLPKTKSL
      1150       1160       1170       1180       1190       1200
RLDPPPGAPP ARPPGLTKVP RRAHTLEREV PGIEELLVSG RHPSMPAFPG LLTAPPGHRS
      1210       1220       1230       1240       1250       1260
HQTCPDDPCE DPGPPPPVQL AKNWTFPNTR TAGSSSDPFL CPPRQLEGLP RTPMALPVDR
      1270       1280       1290       1300       1310       1320
KQSVDPSRTS TPQGPAFGGS RTPSTSDMGE EGRVASGGAP GLETSESLSD SLYDSLSSCG

SQG

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6GQX2-1-unknown	MDQPAG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6GQX2-768-unknown	VELAKS...	768	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29193
Q6GQX2-768-unknown	VELAKS...	768	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30595

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ERPTSP	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123858
...SCLTKV	767	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29193
...SCLTKV	767	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30595
...FPPPDH	1123	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000125080
...CGSQG	1323	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	767	LTKV.\|.VELA	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	767	LTKV.\|.VELA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> NCK5L_MOUSE @767

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)