Q6NV83: U2 snRNP-associated SURP motif-containing protein

General Information

Protein names	- U2 snRNP-associated SURP motif-containing protein - 140 kDa Ser/Arg-rich domain protein - U2-associated protein SR140
Gene names	U2surp
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6NV83

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of U2 snRNP-associated SURP motif-containing protein - Isoform 3 of U2 snRNP-associated SURP motif-containing protein

Sequence View

        10         20         30         40         50         60
MADKTPGGSQ KASSKNRSSD VHSSGSSDAH MDASGPSDSD MPSRTRPKSP RKHNYRNESS
        70         80         90        100        110        120
RESLCDSPHQ NLSRPLLENK LKAFSIGKMS TAKRTLSKKE QEELKKKEDE KAAAEIYEEF
       130        140        150        160        170        180
LAAFEGSDGN KVKTFVRGGV VNAAKDEHET DEKRGKIYKP SSRFADQKNP PNQSSNERPP
       190        200        210        220        230        240
SLLVIETKKP PLKKGEKEKK KSNLELFKEE LKQIQEERDE RHKTKGRLSR FEPPQSDSDG
       250        260        270        280        290        300
QRRSMDVPSR RNRSSGVLDD YAPGSHDVGD PSTTNLYLGN INPQMNEEML CQEFGRFGPL
       310        320        330        340        350        360
ASVKIMWPRT DEERARERNC GFVAFMNRRD AERALKNLNG KMIMSFEMKL GWGKAVPIPP
       370        380        390        400        410        420
HPIYIPPSMM EHTLPPPPSG LPFNAQPRER LKNPNAPMLP PPKNKEDFEK TLSQAIVKVV
       430        440        450        460        470        480
IPTERNLLAL IHRMIEFVVR EGPMFEAMIM NREINNPMFR FLFENQTPAH VYYRWKLYSI
       490        500        510        520        530        540
LQGDSPTKWR TEDFRMFKNG SFWRPPPLNP YLHGMSEEQE TEAFVEEPSK KGALKEEQRD
       550        560        570        580        590        600
KLEEILRGLT PRKNDIGDAM VFCLNNAEAA EEIVDCITES LSILKTPLPK KIARLYLVSD
       610        620        630        640        650        660
VLYNSSAKVA NASYYRKFFE TKLCQIFSDL NATYRTIQGH LQSENFKQRV MTCFRAWEDW
       670        680        690        700        710        720
AIYPEPFLIK LQNIFLGLVN IIEEKETEDV PDDLDGAPIE EELDGAPLED VDGIPIDATP
       730        740        750        760        770        780
IDDLDGVPIK SLDDDLDGVP LDATEDSKKN EPIFKVAPSK WEAVDESELE AQAVTTSKWE
       790        800        810        820        830        840
LFDQHEESEE EENQNQEEES EDEEDTQSSK SEEHHLYSNP VREEATESKF SKYSEMSEEK
       850        860        870        880        890        900
RAKLREIELK VMKFQDELES GKRPKKPGQS FQEQVEHYRD KLLQREKEKE LERERERDKK
       910        920        930        940        950        960
DKEKLESRSK DKKEKDECTP TRKERKRRHS TSPSPSRSSS GRRVKSPSPK SERSERSERS
       970        980        990       1000       1010       1020
HKESSRSRSS HKDSPRDASK KAKRSPSGSR TPKRSRRSRS RSPKKSGKKS RSQSRSPHRS

HKKSKKNKH         10         20         30         40         50         60
MADKTPGGSQ KASSKNRSSD VHSSGSSDAH MDASGPSDSD MPSRTRPKSP RKHNYRNESS
        70         80         90        100        110        120
RESLCDSPHQ NLSRPLLENK LKAFSIGKMS TAKRTLSKKE QEELKKKEDE KAAAEIYEEF
       130        140        150        160        170        180
LAAFEGSDGN KVKTFVRGGV VNAAKDEHET DEKRGKIYKP SSRFADQKNP PNQSSNERPP
       190        200        210        220        230        240
SLLVIETKKP PLKKGEKEKK KSNLELFKEE LKQIQEERDE RHKTKGRLSR FEPPQSDSDG
       250        260        270        280        290        300
QRRSMDVPSR RNRSSGVLDD YAPGSHDVGD PSTTNLYLGN INPQMNEEML CQEFGRFGPL
       310        320        330        340        350        360
ASVKIMWPRT DEERARERNC GFVAFMNRRD AERALKNLNG KMIMSFEMKL GWGKAVPIPP
       370        380        390        400        410        420
HPIYIPPSMM EHTLPPPPSG LPFNAQPRER LKNPNAPMLP PPKNKEDFEK TLSQAIVKVV
       430        440        450        460        470        480
IPTERNLLAL IHRMIEFVVR EGPMFEAMIM NREINNPMFR FLFENQTPAH VYYRWKLYSI
       490        500        510        520        530        540
LQGDSPTKWR TEDFRMFKNG SFWRPPPLNP YLHGMSEEQE TEAFVEEPSK KGALKEEQRD
       550        560        570        580        590        600
KLEEILRGLT PRKNDIGDAM VFCLNNAEAA EEIVDCITES LSILKTPLPK KIARLYLVSD
       610        620        630        640        650        660
VLYNSSAKVA NASYYRKFFE TKLCQIFSDL NATYRTIQGH LQSENFKQRV MTCFRAWEDW
       670        680        690        700        710        720
AIYPEPFLIK LQNIFLGLVN IIEEKETEDV PDDLDGAPIE EELDGAPLED VDGIPIDATP
       730        740        750        760        770        780
IDDLDGVPIK SLDDDLDGVP LDATEDSKKN EPIFKVAPSK WEAVDESELE AQAVTTSKWE
       790        800        810        820        830        840
LFDQHEESEE EENQNQEEES EDEEDTQSSK SEEHHLYSNP VREEATESKF SKYSEMSEEK
       850        860        870        880        890        900
RAKLREIELK VMKFQDELES GKRPKKPGQS FQEQVEHYRD KLLQREKEKE LERERERDKK
       910        920        930        940        950        960
DKEKLESRSK DKKEKDECTP TRKERKRRHS TSPSPSRSSS GRRVKSPSPK SERSERSERS
       970        980        990       1000       1010       1020
HKESSRSRSS HKDSPRDASK KAKRSPSGSR TPKRSRRSRS RSPKKSGKKS RSQSRSPHRS

HKKSKKNKH

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q6NV83-2-unknown	MADKTP...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q6NV83-2-unknown	MADKTP...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6NV83-1-unknown	MADKTP...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt90593
Q6NV83-1-unknown	MADKTP...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt90594
Q6NV83-2-Acetylation	ADKTPG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6NV83-2-Acetylation	ADKTPG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110730
Q6NV83-2-Acetylation	ADKTPG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110731
Q6NV83-2-Acetylation	ADKTPG...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q6NV83-204-unknown	LELFKE...	204		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34014
Q6NV83-204-unknown	LELFKE...	204		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145161
Q6NV83-204-unknown	LELFKE...	204		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146689

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KKKSNL	203	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34014
...KKKSNL	203	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128449
...KKKSNL	203	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129999
...KKNKH	1029	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KKNKH	1029	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86212
...KKNKH	1029	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86211

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	203	KSNL.\|.LELF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)