Q6NYC8: Phostensin

General Information

Protein names	- Phostensin - Protein phosphatase 1 F-actin cytoskeleton-targeting subunit - Protein phosphatase 1 regulatory subunit 18
Gene names	PPP1R18
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6NYC8

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Phostensin - Isoform 3 of Phostensin - Isoform 4 of Phostensin

Sequence View

        10         20         30         40         50         60
MATIPDWKLQ LLARRRQEEA SVRGREKAER ERLSQMPAWK RGLLERRRAK LGLSPGEPSP
        70         80         90        100        110        120
VLGTVEAGPP DPDESAVLLE AIGPVHQNRF IRQERQQQQQ QQQRSEELLA ERKPGPLEAR
       130        140        150        160        170        180
ERRPSPGEMR DQSPKGRESR EERLSPRETR ERRLGIGGAQ ELSLRPLEAR DWRQSPGEVG
       190        200        210        220        230        240
DRSSRLSEAW KWRLSPGETP ERSLRLAESR EQSPRRKEVE SRLSPGESAY QKLGLTEAHK
       250        260        270        280        290        300
WRPDSRESQE QSLVQLEATE WRLRSGEERQ DYSEECGRKE EWPVPGVAPK ETAELSETLT
       310        320        330        340        350        360
REAQGNSSAG VEAAEQRPVE DGERGMKPTE GWKWTLNSGK AREWTPRDIE AQTQKPEPPE
       370        380        390        400        410        420
SAEKLLESPG VEAGEGEAEK EEAGAQGRPL RALQNCCSVP SPLPPEDAGT GGLRQQEEEA
       430        440        450        460        470        480
VELQPPPPAP LSPPPPAPTA PQPPGDPLMS RLFYGVKAGP GVGAPRRSGH TFTVNPRRSV
       490        500        510        520        530        540
PPATPATPTS PATVDAAVPG AGKKRYPTAE EILVLGGYLR LSRSCLAKGS PERHHKQLKI
       550        560        570        580        590        600
SFSETALETT YQYPSESSVL EELGPEPEVP SAPNPPAAQP DDEEDEEELL LLQPELQGGL
       610
RTKALIVDES CRR         10         20         30         40         50         60
MATIPDWKLQ LLARRRQEEA SVRGREKAER ERLSQMPAWK RGLLERRRAK LGLSPGEPSP
        70         80         90        100        110        120
VLGTVEAGPP DPDESAVLLE AIGPVHQNRF IRQERQQQQQ QQQRSEELLA ERKPGPLEAR
       130        140        150        160        170        180
ERRPSPGEMR DQSPKGRESR EERLSPRETR ERRLGIGGAQ ELSLRPLEAR DWRQSPGEVG
       190        200        210        220        230        240
DRSSRLSEAW KWRLSPGETP ERSLRLAESR EQSPRRKEVE SRLSPGESAY QKLGLTEAHK
       250        260        270        280        290        300
WRPDSRESQE QSLVQLEATE WRLRSGEERQ DYSEECGRKE EWPVPGVAPK ETAELSETLT
       310        320        330        340        350        360
REAQGNSSAG VEAAEQRPVE DGERGMKPTE GWKWTLNSGK AREWTPRDIE AQTQKPEPPE
       370        380        390        400        410        420
SAEKLLESPG VEAGEGEAEK EEAGAQGRPL RALQNCCSVP SPLPPEDAGT GGLRQQEEEA
       430        440        450        460        470        480
VELQPPPPAP LSPPPPAPTA PQPPGDPLMS RLFYGVKAGP GVGAPRRSGH TFTVNPRRSV
       490        500        510        520        530        540
PPATPATPTS PATVDAAVPG AGKKRYPTAE EILVLGGYLR LSRSCLAKGS PERHHKQLKI
       550        560        570        580        590        600
SFSETALETT YQYPSESSVL EELGPEPEVP SAPNPPAAQP DDEEDEEELL LLQPELQGGL
       610
RTKALIVDES CRR         10         20         30         40         50         60
MATIPDWKLQ LLARRRQEEA SVRGREKAER ERLSQMPAWK RGLLERRRAK LGLSPGEPSP
        70         80         90        100        110        120
VLGTVEAGPP DPDESAVLLE AIGPVHQNRF IRQERQQQQQ QQQRSEELLA ERKPGPLEAR
       130        140        150        160        170        180
ERRPSPGEMR DQSPKGRESR EERLSPRETR ERRLGIGGAQ ELSLRPLEAR DWRQSPGEVG
       190        200        210        220        230        240
DRSSRLSEAW KWRLSPGETP ERSLRLAESR EQSPRRKEVE SRLSPGESAY QKLGLTEAHK
       250        260        270        280        290        300
WRPDSRESQE QSLVQLEATE WRLRSGEERQ DYSEECGRKE EWPVPGVAPK ETAELSETLT
       310        320        330        340        350        360
REAQGNSSAG VEAAEQRPVE DGERGMKPTE GWKWTLNSGK AREWTPRDIE AQTQKPEPPE
       370        380        390        400        410        420
SAEKLLESPG VEAGEGEAEK EEAGAQGRPL RALQNCCSVP SPLPPEDAGT GGLRQQEEEA
       430        440        450        460        470        480
VELQPPPPAP LSPPPPAPTA PQPPGDPLMS RLFYGVKAGP GVGAPRRSGH TFTVNPRRSV
       490        500        510        520        530        540
PPATPATPTS PATVDAAVPG AGKKRYPTAE EILVLGGYLR LSRSCLAKGS PERHHKQLKI
       550        560        570        580        590        600
SFSETALETT YQYPSESSVL EELGPEPEVP SAPNPPAAQP DDEEDEEELL LLQPELQGGL
       610
RTKALIVDES CRR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6NYC8-1-unknown	MATIPD...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6NYC8-1-unknown	MATIPD...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86011
Q6NYC8-158-unknown	GAQELS...	158	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171723
Q6NYC8-158-	GAQELS...	158		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6NYC8-469-unknown	GHTFTV...	469		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q6NYC8-469-	GHTFTV...	469		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q6NYC8-469-	GHTFTV...	469		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q6NYC8-469-	GHTFTV...	469		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q6NYC8-496-	AAVPGA...	496		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ESCRR	613	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)