TopFIND 4.0

Q6P4E1: Protein CASC4 {ECO:0000305}

General Information

Protein names
- Protein CASC4 {ECO:0000305}
- Cancer susceptibility candidate gene 4 protein
Gene names CASC4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q6P4E1

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVGFGANRRA GRLPSLVLVV LLVVIVVLAF NYWSISSRHV LLQEEVAELQ GQVQRTEVAR 
        70         80         90        100        110        120 
GRLEKRNSDL LLLVDTHKKQ IDQKEADYGR LSSRLQAREG LGKRCEDDKV KLQNNISYQM 
       130        140        150        160        170        180 
ADIHHLKEQL AELRQEFLRQ EDQLQDYRKN NTYLVKRLEY ESFQCGQQMK ELRAQHEENI 
       190        200        210        220        230        240 
KKLADQFLEE QKQETQKIQS NDGKELDINN QVVPKNIPKV AENVADKNEE PSSNHIPHGK 
       250        260        270        280        290        300 
EQIKRGGDAG MPGIEENDLA KVDDLPPALR KPPISVSQHE SHQAISHLPT GQPLSPNMPP 
       310        320        330        340        350        360 
DSHINHNGNP GTSKQNPSSP LQRLIPGSNL DSEPRIQTDI LKQATKDRVS DFHKLKQSRF 
       370        380        390        400        410        420 
FDENESPVDP QHGSKLADYN GDDGNVGEYE ADKQAELAYN EEEDGDGGEE DVQDDEEREL 
       430    
QMDPADYGKQ HFNDVL

Isoforms

- Isoform 2 of Protein CASC4 - Isoform 3 of Protein CASC4 - Isoform 4 of Protein CASC4 - Isoform 5 of Protein CASC4

Sequence View

        10         20         30         40         50         60 
MVGFGANRRA GRLPSLVLVV LLVVIVVLAF NYWSISSRHV LLQEEVAELQ GQVQRTEVAR 
        70         80         90        100        110        120 
GRLEKRNSDL LLLVDTHKKQ IDQKEADYGR LSSRLQAREG LGKRCEDDKV KLQNNISYQM 
       130        140        150        160        170        180 
ADIHHLKEQL AELRQEFLRQ EDQLQDYRKN NTYLVKRLEY ESFQCGQQMK ELRAQHEENI 
       190        200        210        220        230        240 
KKLADQFLEE QKQETQKIQS NDGKELDINN QVVPKNIPKV AENVADKNEE PSSNHIPHGK 
       250        260        270        280        290        300 
EQIKRGGDAG MPGIEENDLA KVDDLPPALR KPPISVSQHE SHQAISHLPT GQPLSPNMPP 
       310        320        330        340        350        360 
DSHINHNGNP GTSKQNPSSP LQRLIPGSNL DSEPRIQTDI LKQATKDRVS DFHKLKQSRF 
       370        380        390        400        410        420 
FDENESPVDP QHGSKLADYN GDDGNVGEYE ADKQAELAYN EEEDGDGGEE DVQDDEEREL 
       430    
QMDPADYGKQ HFNDVL         10         20         30         40         50         60 
MVGFGANRRA GRLPSLVLVV LLVVIVVLAF NYWSISSRHV LLQEEVAELQ GQVQRTEVAR 
        70         80         90        100        110        120 
GRLEKRNSDL LLLVDTHKKQ IDQKEADYGR LSSRLQAREG LGKRCEDDKV KLQNNISYQM 
       130        140        150        160        170        180 
ADIHHLKEQL AELRQEFLRQ EDQLQDYRKN NTYLVKRLEY ESFQCGQQMK ELRAQHEENI 
       190        200        210        220        230        240 
KKLADQFLEE QKQETQKIQS NDGKELDINN QVVPKNIPKV AENVADKNEE PSSNHIPHGK 
       250        260        270        280        290        300 
EQIKRGGDAG MPGIEENDLA KVDDLPPALR KPPISVSQHE SHQAISHLPT GQPLSPNMPP 
       310        320        330        340        350        360 
DSHINHNGNP GTSKQNPSSP LQRLIPGSNL DSEPRIQTDI LKQATKDRVS DFHKLKQSRF 
       370        380        390        400        410        420 
FDENESPVDP QHGSKLADYN GDDGNVGEYE ADKQAELAYN EEEDGDGGEE DVQDDEEREL 
       430    
QMDPADYGKQ HFNDVL         10         20         30         40         50         60 
MVGFGANRRA GRLPSLVLVV LLVVIVVLAF NYWSISSRHV LLQEEVAELQ GQVQRTEVAR 
        70         80         90        100        110        120 
GRLEKRNSDL LLLVDTHKKQ IDQKEADYGR LSSRLQAREG LGKRCEDDKV KLQNNISYQM 
       130        140        150        160        170        180 
ADIHHLKEQL AELRQEFLRQ EDQLQDYRKN NTYLVKRLEY ESFQCGQQMK ELRAQHEENI 
       190        200        210        220        230        240 
KKLADQFLEE QKQETQKIQS NDGKELDINN QVVPKNIPKV AENVADKNEE PSSNHIPHGK 
       250        260        270        280        290        300 
EQIKRGGDAG MPGIEENDLA KVDDLPPALR KPPISVSQHE SHQAISHLPT GQPLSPNMPP 
       310        320        330        340        350        360 
DSHINHNGNP GTSKQNPSSP LQRLIPGSNL DSEPRIQTDI LKQATKDRVS DFHKLKQSRF 
       370        380        390        400        410        420 
FDENESPVDP QHGSKLADYN GDDGNVGEYE ADKQAELAYN EEEDGDGGEE DVQDDEEREL 
       430    
QMDPADYGKQ HFNDVL         10         20         30         40         50         60 
MVGFGANRRA GRLPSLVLVV LLVVIVVLAF NYWSISSRHV LLQEEVAELQ GQVQRTEVAR 
        70         80         90        100        110        120 
GRLEKRNSDL LLLVDTHKKQ IDQKEADYGR LSSRLQAREG LGKRCEDDKV KLQNNISYQM 
       130        140        150        160        170        180 
ADIHHLKEQL AELRQEFLRQ EDQLQDYRKN NTYLVKRLEY ESFQCGQQMK ELRAQHEENI 
       190        200        210        220        230        240 
KKLADQFLEE QKQETQKIQS NDGKELDINN QVVPKNIPKV AENVADKNEE PSSNHIPHGK 
       250        260        270        280        290        300 
EQIKRGGDAG MPGIEENDLA KVDDLPPALR KPPISVSQHE SHQAISHLPT GQPLSPNMPP 
       310        320        330        340        350        360 
DSHINHNGNP GTSKQNPSSP LQRLIPGSNL DSEPRIQTDI LKQATKDRVS DFHKLKQSRF 
       370        380        390        400        410        420 
FDENESPVDP QHGSKLADYN GDDGNVGEYE ADKQAELAYN EEEDGDGGEE DVQDDEEREL 
       430    
QMDPADYGKQ HFNDVL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)